autoimmune disorders (4) Flashcards

1
Q

what is when the immune system mistakes a part of your body as foreign and attacks
-B cells reproduce
-systemic inflammation

A

autoimmune disorder

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2
Q

what are risk factors for autoimmune diseases?

A

-women
-hereditary
-diet (milk/meat)
-environmental (carcinogens)
-viruses

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3
Q

what are symptoms of autoimmune diseases (vary person/person)

A

-fatigue
-achy muscles
-low-grade fever
-trouble concentrating
-hair loss
-skin rashes

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4
Q

what lab is seen in lupus/RA

A

antinuclear antibodies (ANA)

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5
Q

what lab detects nonspecific inflammation in the body. an elevated sed rate does suggest there is an ongoing inflammatory process in body, doesnt indicate where/why

A

erythrocyte sedimentation rate (ESR)

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6
Q

which lab is systemic inflammation may cause a false positive result (if systemic inflammation)

A

VDRL (serum syphilis test)

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7
Q

what may show antigen-antibody clumps blocking glomerulus

A

kidney biopsy

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8
Q

what is an inflammatory autoimmune disease with multiple organ involvement
-antibody-antigen complexes trapped in capillaries
-antibodies destroy host cell

A

systemic lupus erythematosus (SLE)

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9
Q

what are manifestations of systemic lupus erythematosus (SLE)

A

-chronic/acute stress
-fever
-malaise
-butterfly rash
-joint/muscle pain
-pericarditis
-nephritis

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10
Q

what complications of systemic lupus erythematosus (SLE) need to be prevented

A

-renal failure
-CVA/MI
-pain

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11
Q

what is done to the immune system to help systemic lupus erythematosus (SLE)

A

immunosuppression

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12
Q

what drugs are used for lupus?

A

-corticosteroids
-monoclonal antibodies (belimumab)
-NSAIDS

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13
Q

what nursing management is done for systemic lupus erythematosus (SLE)

A

-emotional support
-avoid sun/UV
-infection prevention
-diet recommendation

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14
Q

what is the most common autoimmune disease

A

Sjogren’s

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15
Q

what is a systemic autoimmune disease affecting lacrimal and salivary glands

A

Sjogren’s syndrome

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16
Q

what are manifestations of Sjogren’s syndrome

A

-dry eyes/mouth
-thick mucous
-difficulty swallowing
-skin rash
-reynauds

17
Q

what is used for the diagnosis of Sjogren’s

A

-ocular/gland testing
-symptoms
-labs (ANA elevated)

18
Q

medical management of Sjogren’s

A

symptom management

19
Q

drug therapy for Sjogren’s

A

-artificial tears
-biotene rinse

20
Q

nursing management for Sjogren’s

A

-diet change
-infection prevention

21
Q

what are other autoimmune diseases

A

IBD
-MS
-guillain-barre
-scleroderma
-psoriasis

22
Q

what anti-inflammatory drugs are used for autoimmune diseases?

A

celecoxib

23
Q

which corticosteroid is for autoimmine diseases

A

prednisone

24
Q

what immune modulator is for autoimmune diseases

A

adalimumab

25
Q

which immunosuppressant is for autoimmune diseases

A

methotrexate

26
Q

T/F?
autoimmune disorders only target 1 organ

A

false

27
Q

autoantibodies that attack structures in the nucleus of cells. different patterns are correlated with different diseases

A

Antinuclear antibodies