TABLE 08 - Immunodeficiency

Question 1

Allows cancer and bacterial, viral, fungal, and protozoan diseases; caused by HIV infection

Answer 1

Acquired immunodeficiency syndrome (AIDS)

Question 2

Affects about 1 in 700; causes frequent mucosal infections; specific cause uncertain

Answer 2

Selective IgA immunodeficiency

Question 3

Frequent viral and bacterial infections; second most common immune deficiency affecting about 1 in 70,000; inherited

Answer 3

Common variable hypogammaglobulinemia

Question 4

Usually fatal in early infancy; very rare; inherited; bone marrow transplant a possible treatment

Answer 4

Reticular dysgenesis

Question 5

Affects about 1 in 100,000; allows severe infections; inherited; treated with bone marrow and fetal thymus transplants, gene therapy treatment is promising

Answer 5

Severe combined immunodeficiency (SCID)

Question 6

Absence of cell-mediated immunity; due to the failure of the thymus to develop in embryo

Answer 6

Thymic aplasia (DiGeorge syndrome)

Question 7

Frequent infections by viruses, fungi, protozoa; causes eczema, defective blood clotting; usually causes death in childhood

Answer 7

Wiskott-Aldrich syndrome

Question 8

Frequent extracellular bacterial infections; affects about 1 in 200,000; the first immunodeficiency disorder recognized

Answer 8

X-linked infantile agammaglobulinemia