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[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) > FINAL 03 - Arthropod-Borne and Rodent-Borne Viruses > Flashcards

FINAL 03 - Arthropod-Borne and Rodent-Borne Viruses Flashcards

1
Q

Refers to a group of arthropod-borne viruses; has members from Bunyaviridae, Flaviviridae, Reoviridae, and Togaviridae

A

Arboviruses

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2
Q

The __________ family is initially included under Togaviridae “group B arboviruses”

A

Flaviviridae

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3
Q

Resembles dengue; more likely to cause high fever and maculopapular rash (Examples of undifferentiated fevers)

A

Chikungunya

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4
Q

Chikungunya is caused by the __________ virus, a member of the Togaviridae family

A

Chikungunya virus

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5
Q

Chikungunya is caused by the Chikungunya virus, a member of the __________ family

A

Togaviridae family

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6
Q

2 vectors of chikungunya (AA, AA)

A

Aedes aegypti, Aedes albopictus

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7
Q

A virus that is a member of Flaviviridae; causes fever, headache, muscle and joint pain, and microcephaly (in utero infection)

A

Zika virus

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8
Q

Zika virus is a member of the __________ family

A

Flaviviridae family

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9
Q

Vector of Zika virus

A

Aedes aegypti

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10
Q

Is a zoonosis primarily from domestic livestock; a short-lived mild febrile illness with almost always complete recovery (Examples of undifferentiated fevers)

A

Rift valley fever

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11
Q

Rift valley fever is caused by __________ from the Bunyaviridae family

A

Phlebovirus

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12
Q

Rift valley fever is caused by Phlebovirus from the __________ family

A

Bunyaviridae

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13
Q

Characterized by small itching papules, headache, malaise, nausea, fever, and photophobia (Examples of undifferentiated fevers)

A

Pappataci fever/Sandfly fever/Phlebotomous fever

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14
Q

Pappataci fever is caused by __________ from the Bunyaviridae family

A

Phlebovirus

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15
Q

Pappataci fever is caused by Phlebovirus from the __________ family

A

Bunyaviridae family

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16
Q

Vector of Pappataci fever

A

Phlebotomus papatasi (Female sandfly)

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17
Q

Characterized by fever, thrombocytopenia, leukopenia, and elevated liver enzymes (Examples of undifferentiated fevers)

A

Severe fever with thrombocytopenia syndrome

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18
Q

Severe fever with thrombocytopenia syndrome is caused by __________ from the Bunyaviridae family

A

Phlebovirus

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19
Q

Severe fever with thrombocytopenia syndrome is caused by Phlebovirus from the __________ family

A

Bunyaviridae family

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20
Q

Vector of severe fever with thrombocytopenia syndrome

A

Tick

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21
Q

Virus that causes fever, fatigue, anorexia, nausea, diarrhea, leukopenia, thrombocytopenia, and elevated liver enzymes

A

Heartland virus

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22
Q

Heartland virus is a member of __________ from Bunyaviridae family

A

Phlebovirus

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23
Q

Heartland virus is a member of Phlebovirus from __________ family

A

Bunyaviridae family

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24
Q

Vector of Heartland virus

A

Amblyomma americanum (Lone star tick)

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25
Q

Is self-limited; is a mild febrile disease characterized by a sudden onset of fever, headache, myalgia, arthralgia, lethargy, nausea, and vomiting (Examples of undifferentiated fevers)

A

Colorado tick fever/Mountain fever/Tick fever

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26
Q

Colorado tick fever is caused by __________ from Reoviridae family

A

Coltivirus

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27
Q

Colorado tick fever is caused by Coltivirus from __________ family

A

Reoviridae family

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28
Q

Vector of Colorado tick fever

A

Dermacentor andersoni (Wood tick)

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29
Q

Characterized by sudden of fever, chills, and headache; can progress to hepatorenal failure (Examples of hemorrhagic fevers)

A

Yellow fever

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30
Q

Yellow fever is caused by __________, the prototype virus of Flaviviridae family

A

Yellow fever virus

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31
Q

Yellow fever is caused by yellow fever virus, the prototype virus of __________ family

A

Flaviviridae

32
Q

Vector of yellow fever

A

Aedes aegypti

33
Q

Prevention for yellow fever

A

Live attenuated vaccine

34
Q

Characterized by a febrile, critical, and recovery phase (Examples of hemorrhagic fevers)

A

Dengue fever/Breakbone fever

35
Q

2 vectors of dengue fever (AA, AA)

A

Aedes aegypti, Aedes albopictus

36
Q

Dengue fever is caused by the __________ virus, a member of Flaviviridae family

A

Dengue virus

37
Q

Dengue fever is caused by the dengue virus, a member of __________ family

A

Flaviviridae

38
Q

The dengue virus has __________ serotypes

39
Q

Phase characterized by prodromal symptoms of malaise, chills, and headache (Phases of dengue fever)

A

Febrile phase

40
Q

Type of fever that is common in DHF and severe dengue fever

A

Saddleback/Biphasic fever

41
Q

Phase preceded by a rapid decline in platelet count and increased hematocrit (Phases of dengue fever)

A

Critical phase

42
Q

Phase characterized by a gradual reabsorption of extravascular fluid for 2-3 days and bradycardia (Phases of dengue fever)

A

Recovery phase

43
Q

Also known as Philippine, Thai, or Singapore hemorrhagic fever, Hemorrhagic dengue, and Acute infectious thrombocytopenic purpura (Clinical findings of dengue virus)

A

Dengue hemorrhagic fever

44
Q

Can lead to severe bleeding, organ impairment, and life-threatening shock (Clinical findings of dengue virus)

A

Dengue hemorrhagic fever

45
Q

A severe case of dengue hemorrhagic fever; a protein-losing shock syndrome (Clinical findings of dengue virus)

A

Dengue shock syndrome

46
Q

A tetravalent, live-attenuated dengue vaccine given to 9-16 y/o in 3 doses, 6 months apart

A

Dengvaxia vaccine

47
Q

Has an incubation period of 4-21 days; characterized by a sudden onset of severe headache, chills, fever, nausea, vomiting, generalized pains, and malaise

A

Encephalitis

48
Q

Are viruses that cause hemorrhagic fevers; transmitted from rodents through contact with body fluids or excretions

A

Rodent-borne viruses

49
Q

An acute viral infection that causes an interstitial nephritis that can lead to acute renal insufficiency and renal failure (Rodent-borne illnesses)

A

Hemorrhagic fever with renal syndrome (HFRS)

50
Q

Hemorrhagic fever with renal syndrome (HFRS) is caused by __________, a member of the Bunyaviridae family

A

Hantavirus

51
Q

Hemorrhagic fever with renal syndrome (HFRS) is caused by Hantavirus, a member of the __________ family

A

Bunyaviridae family

52
Q

Vector of hemorrhagic fever with renal syndrome (HFRS)

A

Peromyscus maniculatus (Deer mouse)

53
Q

Not a hemorrhagic fever; is generally severe with a morality rate of ≥30%; characterized by fever, headache, myalgia, and rapidly progressive pulmonary edema (Rodent-borne illnesses)

A

Hantavirus pulmonary syndrome

54
Q

Hantavirus pulmonary syndrome is caused by __________, a member of Bunyaviridae family

A

Hantavirus

55
Q

Hantavirus pulmonary syndrome is caused by Hantavirus, a member of __________ family

A

Bunyaviridae family

56
Q

Vector of Hantavirus pulmonary syndrome

A

Peromyscus maniculatus (Deer mouse)

57
Q

2 diseases characterized by fever, vomiting, back and chest pain, and deafness (Rodent-borne illnesses) (LL)

A

Lassa fever, Lujo fever

58
Q

Lassa fever and Lujo fever is caused by __________ virus and __________ virus, which are members of the Arenaviridae family (LL)

A

Lassa virus, Lujo virus

59
Q

Lassa fever and Lujo fever is caused by Lassa virus and Lujo virus, which are members of the __________ family

A

Arenaviridae family

60
Q

Vector of Lassa fever

A

Mastomys natalensis

61
Q

A group of hemorrhagic fevers wherein bleeding is more common than in Lassa fever

A

South American hemorrhagic fevers

62
Q

South American hemorrhagic fevers are caused by members of the __________ family

A

Arenaviridae family

63
Q

Other name of Junin hemorrhagic fever (Examples of South American hemorrhagic fevers)

A

Argentine hemorrhagic fever

64
Q

Other name of Machupo hemorrhagic fever (Examples of South American hemorrhagic fevers)

A

Bolivian hemorrhagic fever

65
Q

Caused by Guanarito virus (Examples of South American hemorrhagic fevers)

A

Venezuelan hemorrhagic fever

66
Q

Vector of South American hemorrhagic fevers

A

Calomys sp.

67
Q

Are hemorrhagic fevers characterized by fever, headache, sore throat, and muscle pain, often leading to shock and death; caused by Marburg and Ebola viruses from the Filoviridae family

A

African hemorrhagic fevers

68
Q

African hemorrhagic fevers are caused by __________ and __________ viruses from the Filoviridae family; is highly virulent in humans and infections usually end in death (ME)

A

Marburg virus, Ebola virus

69
Q

African hemorrhagic fevers are caused by Marburg and Ebola viruses from the __________ family; is highly virulent in humans and infections usually end in death

A

Filoviridae

70
Q

A family of viruses that is long and threadlike; require maximum containment conditions (Biosafety level 4)

A

Filoviridae

71
Q

A member of the Filoviridae family that caused recurrent outbreaks; the largest known outbreak was in western Africa in 2014-2016

A

Ebolavirus

72
Q

Meaning of BOMV (Ebolavirus species that affects humans)

A

Bombali virus

73
Q

Meaning of BDBV (Ebolavirus species that affects humans)

A

Bundibugyo virus

74
Q

Meaning of SUDV (Ebolavirus species that affects humans)

A

Sudan virus

75
Q

Meaning of EBOV; the most severe (Ebolavirus species that affects humans)

A

Zaire ebolavirus (EBOV)

76
Q

Meaning of TAFV (Ebolavirus species that affects other primates)

A

Tai forest virus

77
Q

Meaning of RESTV; is endemic in the Philippines (Ebolavirus species that affects other primates)

A

Reston virus

[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) (39 decks)

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