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[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) > FINAL 06 - Enteroviruses and Respiratory Viruses > Flashcards

FINAL 06 - Enteroviruses and Respiratory Viruses Flashcards

(53 cards)

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1
Q

A genus of viruses that are members of the Picornaviridae family; are transient inhabitants of the human alimentary tract

A

Enteroviruses

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2
Q

Most common form; characterized by fever, malaise and drowsiness (Clinical findings of poliovirus)

A

Abortive/mild disease

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3
Q

Characterized by stiffness and pain in the back and neck; rarely progresses to paralysis (Clinical findings of poliovirus)

A

Nonparalytic poliomyelitis (Aseptic meningitis)

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4
Q

Characterized by flaccid paralysis resulting from lower motor neuron damage; causes residual paralysis (Clinical findings of poliovirus)

A

Paralytic poliomyelitis

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5
Q

Characterized by recrudescence of paralysis and muscle wasting decades after paralysis; more common in women (Clinical findings of poliovirus)

A

Progressive poliomyelitis muscle atrophy (Postpolio syndrome)

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6
Q

Contains formalinized virus; induces production of plasma IgG and IgM (Poliovirus vaccine)

A

Salk/Inactivated polio vaccine (IPV)

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7
Q

Contains live attenuated virus; induces production of IgG, IgM, and intestinal IgA (Poliovirus vaccine)

A

Sabin/Oral polio vaccine (OPV)

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8
Q

Characterized by fever, malaise, headache, nausea, and abdominal pain (Clinical findings of Coxsackievirus A and B)

A

Aseptic meningitis

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9
Q

Characterized by acute onset of fever, malaise, and headache (Clinical findings of Coxsackievirus A and B)

A

Nonspecific febrile illness (Summer Grippe)

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10
Q

Characterized by oral and pharyngeal ulcerations and a vesicular rash of the palms and soles (Clinical findings of Coxsackievirus A)

A

Hand, foot, and mouth disease

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11
Q

Characterized by severe febrile pharyngitis and discrete vesicles on the posterior half of the palate (Clinical findings of Coxsackievirus A)

A

Herpangina

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12
Q

Characterized by severe eye pain, blurred vision, photophobia, and watery discharge (Clinical findings of Coxsackievirus A)

A

Acute hemorrhagic conjunctivitis

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13
Q

Most common cause of viral heart disease; causes pleurodynia, myocarditis, pericarditis, and generalized disease of infants

A

Coxsackievirus B

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14
Q

Characterized by sudden fever and stabbing chest pain, sometimes preceded by malaise, headache, and anorexia (Clinical findings of Coxsackievirus B)

A

Pleurodynia/Epidemic myalgia/Bornholm disease

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15
Q

Characterized by acute inflammation of the heart or its covering membranes (Clinical findings of Coxsackievirus B)

A

Myocarditis and Pericarditis

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16
Q

An extremely serious disease in which the infant is overwhelmed by a simultaneous infection of multiple organs, including the heart, liver, and brain (Clinical findings of Coxsackievirus B)

A

Generalized disease of infants

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17
Q

A family of viruses that cause aseptic meningitis, encephalitis, febrile illnesses with or without rash, common colds, and ocular disease

A

Echovirus (Enteric, cytopathogenic, human orphan viruses)

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18
Q

An enterovirus that is the chief cause of acute hemorrhagic conjunctivitis

A

Enterovirus 70

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19
Q

A family of viruses that includes the parainfluenza virus, respiratory syncytial virus (RSV), and human metapneumovirus

A

Paramyxoviridae

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20
Q

Most common cause of common colds/URTI and the most common viral culprit in asthma exacerbation (Genus of respiratory viruses)

A

Rhinovirus

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21
Q

Has the largest genome among RNA viruses; causes common colds, LRTI, and gastroenteritis (Genus of respiratory viruses)

A

Coronaviridae

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22
Q

Club or petal-shaped projections in Coronaviridae that are widely spaced on the outer surface of the envelope

23
Q

Caused serious respiratory illness including pneumonia and progressive respiratory failure; an outbreak of it happened in 2003 in Southern China (Members of Coronaviridae)

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A

Severe acute respiratory syndrome coronavirus (SARS-COV)

24
Q

Caused pneumonia and respiratory failure; an outbreak of it happened in 2012 in Saudi Arabia (Members of Coronaviridae)

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A

Middle East Respiratory Syndrome Coronavirus (MERS-COV)

25
Its outbreak started in December 2019 in Wuhan, China; it was declared as a pandemic on March 11, 2020 (Clinical findings of SARS-COV-2)
Coronavirus disease 2019 (COVID-19)
26
Incubation period of COVID-19
2-14 days (5 days on average)
27
Gold standard for diagnosis of COVID-19
Reverse transcription polymerase chain reaction (RT-PCR)
28
A virus that is member of the Orthomyxoviridae family; has 2 glycoprotein spikes in its envelope
Influenza
29
The influenza virus is part of the __________ family
Orthomyxoviridae family
30
2 glycoprotein spikes in influenza virus envelope (HA, NA)
Hemagglutinin, Neuraminidase
31
Binds virus particles to susceptible cells (Glycoprotein spikes in influenza envelope)
Hemagglutinin (HA)
32
Facilitates release of virus particles from infected cell (Glycoprotein spikes in influenza envelope)
Neuraminidase (NA)
33
Involves minor changes; accumulation of point mutations resulting in AA changes in antigens (Influenza antigenic variation)
Antigenic drift
34
Involves major changes; drastic changes in the AA sequence of antigens (Influenza antigenic variation)
Antigenic shift
35
Refers to the combination of parental gene segments when a cell is coinfected by two different viruses; happens in influenza viruses
Genetic reassortment
36
Highly antigenic variable; the only strain that causes pandemics; infects humans and animals (Influenza virus types)
Influenza A
37
May exhibit antigenic changes; sometimes causes epidemics; infects humans only (Influenza virus types)
Influenza B
38
Antigenically stable; causes sporadic cases; infects humans and swine (Influenza virus types)
Influenza C
39
Characterized by sudden onset of chills, headache, and dry cough in Influenza A and B; characterized by common cold in influenza C (Clinical findings of influenza)
Uncomplicated influenza
40
Occurs in elderly adults and debilitated individuals; can be viral, secondary bacterial, or a combination of the two (Clinical findings of influenza)
Pneumonia
41
An acute encephalopathy of children and adolescents; a rare complication of influenza A and B, and herpesvirus varicella-zoster infections (Clinical findings of influenza)
Reye syndrome
42
Grown in embryonated eggs or cell lines; not to be used for people with allergy to egg protein (Vaccines for Influenza A and B)
Inactivated vaccine
43
Is administered intranasally (Vaccines for Influenza A and B)
Live attenuated vaccine
44
A virus that is a member of the Paramyxoviridae family; causes croup
Parainfluenza virus
45
Parainfluenza virus is a member of the __________ family
Paramyxoviridae family
46
A respiratory obstruction caused by swelling of the larynx; characterized by inspiration (stridor) associated with a barky cough (Clinical findings of parainfluenza virus)
Croup (Laryngotracheitis)
47
A virus that is a member of the Paramyxoviridae family; is the most important cause of LRTI in infants and young children
Respiratory syncytial virus (RSV)
48
Respiratory syncytial virus (RSV) is a member of the __________ family
Paramyxoviridae family
49
Inflammation or infection of the bronchioles, the smallest and most highly resistant airways (Clinical findings of RSV)
Bronchiolitis
50
2 treatment for respiratory syncytial virus (RSV) (RP)
Ribavirin, Palivizumab
51
Prophylaxis of RSV hospitalization
Palivizumab
52
A member of the Paramyxoviridae family; is less virulent than RSV; causes cough, coryza, and wheezing
Human metapneumovirus
53
Human metapneumovirus is a member of the __________ family
Paramyxoviridae family

[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) (39 decks)

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