FINAL 09 - Parasitology Flashcards
A symbiotic relationship in which one animal, the parasite, lives at the expense of the other animal, the host
Parasitism
Cannot survive without a host (Types of parasite)
Obligate parasite
Has free-living forms or can act as commensal (Types of parasite)
Facultative parasite
Within the host; infection (Types of parasite)
Endoparasite
The surface of the host; infestation (Types of parasite)
Ectoparasite
Where the adult parasite lives and undergoes sexual reproduction; obligatory to life cycle (Types of host)
Definitive/primary host
Where the larval stage lives and undergoes asexual reproduction; obligatory to life cycle (Types of host)
Intermediate/secondary host
Where the larval stage without further development; not obligatory to life cycle (Types of host)
Parenteric/transport/carrier host
Additional source of infection; not obligatory to life cycle (Types of host)
Reservoir/temporary host
Accidentally harbors the parasite; cannot transmit parasite to definitive host (Types of host)
Accidental/dead-end host
Stage at which the parasite is transmitted to a host (Stages of parasite)
Infective stage
Stage at which the parasite is detected in a specimen from a host (Stages of parasite)
Diagnostic stage
Referred to as “first animals”; are unicellular eukaryotes that inhabit water and soil
Protozoa
Uses pseudopodia or protoplasmic flow for movement (Examples of protozoa)
Amebae
Uses flagella for movement (Examples of protozoa)
Flagellates
Uses cilia for movement; denucleated (Examples of protozoa)
Ciliates
Are nonmotile intracellular parasites; has a complex life cycle, alternating between sexual and asexual reproductive stages (Examples of protozoa)
Apicomplexa
Involves multiple fission (Asexual protozoan reproduction)
Schizogony
Involves fusion of two cells (Sexual protozoan reproduction)
Conjugation
Involves production of haploid gametes and fusion to a diploid zygote (Sexual protozoan reproduction)
Gametogony
Vegetative, growing, and motile form (Protozoan stages)
Trophozoite
Dormant, resistant, and usually infectious form (Protozoan stages)
Cyst
Reproductive structure formed by members of Apicomplexa
Oocyst
The only common pathogenic protozoan found in the duodenum and jejunum of humans; referred to as “old man’s eyeglasses” due to its leaf/heart shape (Intestinal protozoa)
Giardia lamblia/G. duodenalis/G. intestinalis
Characterized by irritation and low-grade inflammation of the duodenal or jejunal mucosa; presence of H2S odor in stool or breath (Clinical findings of Giardia lamblia)
Giardiasis
2 diagnosic tests for Giardia lamblia (ES)
Enterotest/Duodenal capsule/String test, Stool exam
Is an intestinal and tissue ameba; trophozoite is the only form present in tissues; causes amebiasis (Intestinal protozoa)
Entamoeba histolytica
2 types of amebiasis (IE)
Intestinal, Extraintestinal
Amebiasis characterized by diarrhea, abdominal cramps, N/V, tenesmus (Types of amebiasis)
Intestinal amebiasis
Severe dysentery characterized by abdominal tenderness, fulminating dysentery, dehydration, and incapacitation
Amebic dysentery
Granulomatous mass that is sometimes formed due to intestinal amebiasis
Ameboma
Amebiasis that spreads via metastasis and rarely by direct extension; includes amebic hepatitis and pulmonary amebiasis (Types of amebiasis)
Extraintestinal amebiasis
Most common kind of extraintestinal amebiasis; is progressive, nonsuppurative, destructive w/o compression, and formation of a wall
Amebic hepatitis
Entamoeba histolytica causes __________ ucler
Flask-shaped ulcer
A human commensal; is nonpathogenic (Other intestinal amebae)
Entamoeba dispar
Is not a symbiont (Other intestinal amebae)
Entamoeba moshkovskii
Is small and nonpathogenic (Other intestinal amebae)
Entamoeba hartmanni
Is nonpathogenic (Other intestinal amebae)
Entamoeba coli
2 intestinal sporozoan that infects the immunocompromised; causes cryptosporidiosis (CH, CP)
Cryptosporidium hominis, Cryptosporidium parvum
Characterized by severe, intractable watery diarrhea; is self-limited in immunocompetent hosts (Clinical findings of Cryptosporidium sp.)
Cryptosporidiosis
An intestinal sporozoan; causes cyclosporiasis (Intestinal protozoa)
Cyclospora cayetanensis
Characterized by self-limited diarrhea, anorexia, fatigue, and weight loss in immunocompetent hosts; prolonged in immunocompromised (Clinical findings of Cyclospora cayetensis)
Cyclosporiasis
An intestinal sporozoan; predominantly an infection of people in the developing world and a common presentation of HIV/AIDS; causes cystoisosporiasis (Intestinal protozoa)
Cystoisospora belli
Cystoisospora belli is previously called as __________
Isospora belli
Is self limited in immunocompetent individuals and results to prolonged illness in immunocompromised individuals (Clinical findings of Cystoisospora belli)
Cystoisosporiasis
The only ciliate protozoan parasite of humans; the largest protozoan parasite of humans; causes balantidiasis (Intestinal protozoa)
Balantidium coli
Usually asymptomatic; characterized by mucosal ulcers and submucosal abscesses, resembling lesions in amebiasis (Clinical findings of Balantidium coli)
Balantidiasis
A genitourinary flagellate; is anaerobic; causes trichomoniasis (Sexually transmitted protozoa)
Trichomonas vaginalis
Usually asymptomatic or mild; more common in women than men (Clinical findings of Trichomonas vaginalis)
Trichomoniasis
Causes African trypanosomiasis; transmitted through inoculation of metacyclic trypomastigotes by tsetse fly (Trypanosoma species)
Trypanosoma brucei
Trypanosoma brucei is transmitted through inoculation of metacyclic trypomastigotes by __________
Tsetse fly
Characterized by cutaneous, hemolymphatic, and CNS stage (Clinical findings of Trypanosoma brucei)
African trypanosomiasis
Causes Chagas disease; transmitted through inoculation of metacyclic trypomastigotes in the feces of reduviid bugs (Trypanosoma species)
Trypanosoma cruzi
Trypanosoma cruzi is transmitted through inoculation of metacyclic trypomastigotes in the feces of __________
Reduviid bugs
Characterized by Chagoma and Romaña sign in acute stages and chagasic cardiomyopathy and megacolon in chronic stages (Clinical findings of Trypanosoma cruzi)
Chagas disease
Subcutaneous inflammatory nodule at the site of inoculation (Acute stage of Chagas disease)
Chagoma
Unilateral swelling of the eyelids (Acute stage of Chagas disease)
Romaña sign
Characterized by small, red papule, rolled-edge ulceration, and depressed, unpigmented scar (Clinical findings of Leishmania)
Cutaneous leishmaniasis
Characterized by small, red papule, itchy, ulcerated vesicle, and degeneration of cartilaginous and soft tissues in nasal and buccal mucosa (Clinical findings of Leishmania)
Mucocutaneous leishmaniasis
Characterized by post-kala-azar dermal leishmanoid, which are reddish, depigmented nodules (Clinical findings of Leishmania)
Visceral leishmaniasis
Leishmania is transmitted through inoculation of promastigote by __________
Sandfly
Diagnostic test for Leishmania
Amastigotes biopsy
A free-living ameba; an ameboflagellate; causes primary amebic meningoencephalitis (PAM) (Tissue ameba)
Naegleria fowleri
Naegleria fowleri is also known as __________
Naegleria aerobia
An acute, fulminant, rapidly fatal illness characterized by headache and caused by swimming in warm freshwater (Clinical findings of Naegleria fowleri)
Primary amebic meningoencephalitis (PAM)
2 free-living ameba; often associated with immunocompromised individuals; causes granulomatous amebic encephalitis (GAE) (Tissue ameba) (AB)
Acanthamoeba castellani, Balamuthia mandrillaris
Is chronic; characterized by confusion, headache, and seizure (Clinical findings of Acanthamoeba castellani and Balamuthia mandrillaris)
Granulomatous amebic encephalitis (GAE)
A corneal inflammation and opacity; is present in granulomatous amebic encephalitis (GAE) (Clinical findings of Acanthamoeba castellani and Balamuthia mandrillaris)
Acanthamoeba kerititis
Plasmodium vivax (Human or primate malaria)
Human malaria
Plasmodium falciparum (Human or primate malaria)
Human malaria
Plasmodium malariae (Human or primate malaria)
Human malaria
Plasmodium ovale (Human or primate malaria)
Human malaria
Plasmodium knowlesi (Human or primate malaria)
Primate malaria
Blood sporozoan; transmitted through injection of sporozoites via the bite of female Anopheles mosquito (Blood and tissue sporozoa)
Plasmodium sp.
Dormant liver forms of Plasmodium vivax and Plasmodium ovale; can develop into merozoites
Hypnozoites
Number one killer of all parasitic diseases; characterized by periodic paroxysms (Clinical findings of Plasmodium sp.)
Malaria
Cytoplasmic Schuffner dots; enlarged host cells (Plasmodium species) (PV, PO)
Plasmodium vivax, Plasmodium ovale
Band-shaped trophozoite (Plasmodium species)
Plasmodium malariae
Small, often multiply infected rings; banana-shaped gametocytes (Plasmodium species)
Plasmodium falciparum
Recurrence that takes place after complete initial clearing of the erythrocytic infection; happens with Plasmodium vivax and Plasmodium ovale
Relapse
Recurrence of symptoms in a patient whose bloodstream infection has previously been at such a low level as not to be clinically demonstrable or cause symptoms; happens with all Plasmodium species
Recrudescence
Causes benign tertian malaria and tertian ague (q48h) (Plasmodium species)
Plasmodium vivax
Causes mild tertian malaria (q48h); rarest (Plasmodium species)
Plasmodium ovale
Causes aestivoautumnal, malignant tertian, and subtertian malaria (q36-48h); most common and most severe; shortest incubation period (Plasmodium species)
Plasmodium falciparum