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[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) > FINAL 02 - Viral Hepatitis and Gastroenteritis > Flashcards

FINAL 02 - Viral Hepatitis and Gastroenteritis Flashcards

1
Q

A systemic disease primarily involving the liver; produces acute inflammation of the liver

A

Viral hepatitis

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2
Q

Hepatitis wherein more extensive damage may occur that prevents orderly liver cell regeneration

A

Fulminant hepatitis

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3
Q

Chronic carriers of __________ may or may not have demonstrable evidence of liver disease

A

HBsAg

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4
Q

Hepatitis that is a mild benign disease; characterized by abnormal aminotransferase values and hepatomegaly

A

Persistent (Unresolved) viral hepatitis

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5
Q

Hepatitis characterized by inflammation and necrosis to collapse of the normal reticulum framework

A

Chronic active hepatitis

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6
Q

A member of the Picornaviridae family; causes hepatitis A; transmitted through the fecal-oral route (Types of hepatitis virus)

A

Hepatitis A virus (Enterovirus-72)

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7
Q

Hepatitis A virus is a member of the __________ family

A

Picornaviridae family

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8
Q

Hepatitis A virus causes __________

A

Hepatitis A (Infectious hepatitis)

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9
Q

Refers to the Hepatitis A virus (Hepatitis A laboratory findings)

A

HAV

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10
Q

Refers to the antibody to HAV (Hepatitis A laboratory findings)

A

Anti-HAV

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11
Q

Refers to the IgM class antibody to HAV; indicates recent infection with hepatitis A (Hepatitis A laboratory findings)

A

IgM anti-HAV

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12
Q

Prevention for Hepatitis A virus

A

Inactivated vaccine

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13
Q

A member of the Hepadnaviridae family; causes hepatitis B (Serum hepatitis); has reverse transcriptase; transmitted parenterally (Types of hepatitis virus)

A

Hepatitis B virus

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14
Q

Hepatitis B virus is a member of the __________ family

A

Hepadnaviridae family

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15
Q

Hepatitis B virus causes __________

A

Hepatitis B (Serum hepatitis)

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16
Q

Hepatitis B virus has __________, which means it replicated through intermediate RNA, resembling a retrovirus

A

Reverse transcriptase

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17
Q

Virion of Hepatitis B virus

A

Dane particle

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18
Q

Refers to the irreversible fibrosis (scarring) of the liver

A

Liver cirrhosis

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19
Q

People with Hepatitis B are at a higher risk of developing __________

A

Hepatocellular carcinoma

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20
Q

Refers to the hepatitis B virus (Hepatitis B laboratory findings)

A

HBV

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21
Q

Refers to the hepatitis B surface antigen (Hepatitis B laboratory findings)

A

HBsAg

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22
Q

Refers to the hepatitis B e antigen (Hepatitis B laboratory findings)

A

HBeAg

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23
Q

Refers to the hepatitis B core antigen (Hepatitis B laboratory findings)

A

HBcAg

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24
Q

Refers to the antibody to HBsAg; indicates past infection and immunity to HBV (Hepatitis B laboratory findings)

A

Anti-HBs

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25
Refers to the antibody to HBsAg (Hepatitis B laboratory findings)
Anti-HBs
26
Refers to the antibody to HBeAg (Hepatitis B laboratory findings)
Anti-HBe
27
Refers to the antibody to HBcAg; indicates infection with HB at some undefined time in the past (Hepatitis B laboratory findings)
Anti-HBc
28
Refers to the IgM class antibody to HBcAg; indicates recent infection with HBV (Hepatitis B laboratory findings)
IgM anti-HBc
29
A general marker of infection; presence indicates current infection; absence may indicate lack of infection, past infection, or immunization
HBsAg
30
3 treatments given for chronic Hepatitis B infection (PET)
Pegylated interferon alfa-2a, Entecavir, Tenofovir
31
Hepatitis B vaccine given to all newborns
Hepatitis B subunit vaccine (HBsAg)
32
Hepatitis B vaccine given to newborns of infected mothers or within 14 days after sexual exposure
Hepatitis B immunoglobulin (HBIG)
33
Hepatitis C virus is a member of the __________ family, but it is not vector-borne
Flaviviridae family
34
Hepatitis C virus causes __________
Hepatitis C/Non-A hepatitis/Non-B hepatitis/Posttransfusion hepatitis
35
Refers to the Hepatitis C virus (Hepatitis C laboratory findings)
HCV
36
Refers to the antibody to HCV (Hepatitis C laboratory findings)
Anti-HCV
37
Treatment for Hepatitis C (PR)
Pegylated interferon-alfa + Ribavirin
38
A member of the Deltaviridae family; a defective virus dependent on coinfection with HBV; causes hepatitis D (Types of hepatitis virus)
Hepatitis D virus
39
Hepatitis D virus is a member of the __________ family
Deltaviridae family
40
An agent of the Hepatitis D virus that contains delta antigen (HDAg) surrounded by an HBsAg envelope
Delta agent
41
Hepatitis D virus causes __________
Hepatitis D (Delta hepatitis)
42
A severe acute infection; refers to fulminant hepatitis (Clinical findings of Hepatitis D virus)
Coinfection
43
Refers to progression to cirrhosis (Clinical findings of Hepatitis D virus)
Superinfection
44
Refers to the Hepatitis D virus (Hepatitis D laboratory findings)
HDV
45
Refers to the delta antigen; detectable in early acute HDV infection (Hepatitis D laboratory findings)
HDAg
46
Refers to the antibody to delta-Ag; indicates past or present infection with HDV (Hepatitis D laboratory findings)
Anti-HD
47
A member of the Hepeviridae family; causes hepatitis E; responsible for a mortality rate in excess of 20% in pregnant women (Types of hepatitis virus)
Hepatitis E virus
48
Hepatitis E virus is a member of the __________ family
Hepeviridae family
49
Hepatitis E virus causes __________
Hepatitis E (Enterically transmitted hepatitis)
50
Anti-HAV IgM positive is interpreted as _________ (Serologic markers of hepatitis)
Acute infection with HAV
51
Anti-HAV IgG positive is interpreted as __________ (Serologic markers of hepatitis)
Past infection with HAV
52
Anti-HCV positive is interpreted as __________ (Serologic markers of hepatitis)
Current or past infection with HCV
53
Anti-HD positive, HBsAg positive is interpreted as __________ (Serologic markers of hepatitis)
Infection with HDV
54
Anti-HD positive, anti-HBc IgM positive is interpreted as __________ (Serologic markers of hepatitis)
Coinfection with HDV and HBV
55
Anti-HD positive, anti-HBc IgM negative is interpreted as __________ (Serologic markers of hepatitis)
Superinfection of chronic HBV infection with HDV
56
A clinical syndrome which includes not only diarrhea, but also other symptoms like abdominal pain, nausea, and vomiting
Gastroenteritis
57
About 90% of causes of acute viral gastroenteritis are caused by either the __________ or __________ (RN)
Rotavirus, Norovirus
58
The most common cause of viral gastroenteritis; is wheel-shaped; is a member of Reoviridae family
Rotavirus
59
The rotavirus is ________ shaped
Wheel-shaped
60
The rotavirus is a member of the __________ family
Reoviridae
61
Oral live attenuated rhesus-based rotavirus vaccine; withdrawn due to incidence of intussusception (Rotavirus vaccine)
RotaShield
62
Oral live attenuated pentavalent human-bovine reassortant rotavirus vaccine; 3 dose series from 6-32 weeks (Rotavirus vaccine)
RotaTeq
63
Oral live attenuated monovalent human rotavirus vaccine; 2 dose series from 6-24 weeks (Rotavirus vaccine)
Rotarix
64
A member of Caliciviridae family; the most important cause of viral gastroenteritis (winter vomiting disease) in adults
Norovirus/Norwalk virus
65
The norovirus is a member of the __________ family
Caliciviridae family
66
Norovirus is the most important cause of __________ in adults
Epidemic viral gastroenteritis (Winter vomiting disease)
67
A family of viruses that has a starlike morphology; causes sporadic cases of viral gastroenteritis
Astroviridae

[2ND YEAR] CCP 5 - Pharmaceutical Microbiology & Parasitology (Lec) (39 decks)

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