Renal Anatomy/Histology Flashcards
At what vertebral levels do the kidneys extend from?
T12 - L3
Which kidney is slightly lower?
Right Kidney
– Due to the liver
What anatomical plane at L1 runs above the left kidney’s hilum but through the superior pole of the right kidney?
Transpyloric plane
The right kidney is lower; how far is its inferior pole from the right iliac crest?
1 index finger width
What are the 3 points of constriction for the ureters?
- Uretopelvic junction
- Over common or external iliac
- Uretovesical junction
Describe the blood supply from the aorta to the peritubular capillaries?
Aorta Renal Arteries Segmental A. Interlobar A. Arcuate A. Interlobar A. Afferent Arteriole Glomerulus Efferent Arteriole Peritubular capillaries
Describe the order of the blood back through the veins from the peritubular capillaries
Peritubular capillaries Interlobar V. Arcuate V. Interlobar V. Renal V. Inferior Vena Cava
What is the sympathetic innervation to the kidney?
Renal plexus
- Lesser splanchnic (T10-T11)
- Least splanchnic (T12)
- Lumbar Splanchnic (L1-L2)
What ganglion does the renal plexus (sympathetic innervation to the kidney) synapse at?
Aorticorenal
What is the parasympathetic innervation to the kidney?
Vagus N (CNX)
What makes up the Renal Corpuscle?
Glomerulus and Bowman’s Capsule
What makes up a nephron?
Renal corpuscle Proximal Convoluted tubule Proximal Straight tubule Thin loop of Henle Distal straight tubule Distal Convoluted tubule
What makes up a uriniferous tubule?
Nephron and collecting ducts
Job of the uriniferous tubules?
Urine production and concentration
What are cortical (medullary) rays?
Aggregation of collecting ducts and straight tubules in the cortex
What do cortical (medullary) rays run between in the cortex?
Cortical labyrinth
What is included in the cortical labyrinth?
Renal corpuscles and convoluted tubules
What portions of the nephron are in the renal cortex?
Renal Corpuscle
Proximal convoluted tubule
Distal convoluted tubule
What portions of the nephron are in the renal medulla?
Proximal straight tubule
Loop of Henle
What type of endothelium is located at the glomerulus?
Fenestrated
What immediately surrounds the glomerular capillaries?
Bowman’s capsule
What are the 2 layers of Bowman’s capsule?
- Visceral
2. Parietal
What cell type lies in the visceral layer of Bowman’s capsule?
Podocytes
Podocytes extend _____ around capillaries
Pedicels (foot processes)
When pedicels from podocytes connect, what do they form?
Filtration slits
Filtration slits are ______ selective filter
SIZE
What type of epithelium is the parietal layer of Bowman’s capsule?
Simple squamous
What 3 things make up the filtration apparatus?
Fenestrated glomerular endothelium
Glomerular basement membrane
Visceral layer of Bowman’s Capsule
What does the glomerular basement membrane restrict?
Large proteins, like Albumin
Mesangial cells + ECM =
Mesangium
Where is the mesangium located?
Near the vascular pole of the Renal corpuscle
What is a main function of the mesangium?
Contractile - modulates glomerular distention
How can you identify a proximal convoluted tubule on a histo image?
Apical brush border – cloudy lumen
Descending or Ascending loop of Henle - where does water diffuse out?
Descending
Descending or Ascending loop of Henle - where is the loop IMPERMEABLE to water?
Ascending
What portion of the nephron can exchange sodium for potassium under Aldosterone?
Distal Convoluted Tubule
How can you identify collecting tubules/ducts on a histo image?
Cell BOUNDARIES
Job of Macula Densa cells?
Sense low sodium
Where is the juxtaglomerular apparatus located?
Near vascular pole of renal corpuscle and at terminal portion of the distal straight tubule
Where are juxtaglomerular cells?
On the afferent arterioles
What things make up the urinary tract?
Ureters
Bladder
Urethra
What type of epithelium is found at the urinary tract?
Transitional Epithelium – “urothelium”
What shape is the transitional epithelium when the bladder is empty?
Dome shaped
What shape is the transitional epithelium when the bladder is full?
Flat
The Urethra starts out as Transitional Epithelium, what does it end as?
Stratified squamous