Proximal Tubule Renal Transport Flashcards
Where does a majority of the reabsorption occur in the kidney?
Proximal Tubule
What substances specifically are COMPLETELY reabsorbed in the proximal tubule?
Glucose
Amino Acids
Glucose and Amino Acids are reabsorbed where?
Proximal Tubule
What are the borders that solutes must cross in order to be reabsorbed?
From the Tubule Lumen: - Apical border - Navigate through the cell - Basolateral border Enter Peritubular Capillary
For sodium, what usually powers its reabsorption on the basolateral border?
Na+/K+ ATPase
For sodium, what are the types of transporters it uses to cross the apical border and enter the cell?
- Symporters
2. Antiporters
Symporter
2 molecules coming into the cell together
Antiporter
One molecule coming into the cell while another gets kicked out of the cell
Most common sodium symporter on the apical border of the cell?
Na - HCO3
Most common sodium antiporter on the apical border of the cell?
Na - H
Through what channels does water move through a cell?
AQP
Aquaporins
Water moves passively and enters the blood via ____
Bulk flow (follows solutes)
If the ECV decreases (volume contraction), how will this affect the reabsorption of solutes?
INCREASES - water will follow
If the ECV increases (volume expansion), how will this affect the reabsorption of solutes?
DECREASES - water will follow
What occurs at the Thin Descending limb?
Water Reabsorption!
