Development of Great Vessels Flashcards
Where is the aortic sac?
Expansion at distal truncus arteriosus
What arteries arise from the aortic sac?
Aortic Arches (AA)
What do the aortic arches connect?
Aortic sac to the Dorsal Aorta
How many pairs of aortic arches are there?
6 pairs
Through what processes are aortic arches formed?
Vasculogenesis and Angiogenesis
What 3 changes are made to achieve the adult vessel pattern?
- Hypertrophy of some (AA 3, 4, 6)
- Addition of new vessels
- Loss of some vessels
At what spinal level do the dorsal aorta fuse and continue caudally?
T4
What arteries run between somites and connect with the dorsal aorta?
Intersegmental arteries
Cervical intersegmental arteries become?
Vertebral arteries
7th Cervical intersegmental artery becomes what on the left?
Left subclavian
7th Cervical intersegmental artery becomes what on the right?
PORTION of the Right subclavian
Thoracic intersegmental arteries become?
Internal thoracics and Intercostals
Lumbar intersegmental arteries become?
Epigastric and iliac vessels
AA 1
Maxillary A.
AA 2
Stapedial A.
AA 3
Common carotid, proximal internal carotid and external carotid
AA 4 on the left
Part of Aortic Arch
What form the Aortic Arch?
Aortic sac
AA 4 on the left
Left dorsal aorta
AA 4 on the right
Proximal right subclavian A.
AA 5
NEVER REALLY FORMS
AA 6
Pulmonary arteries
On the left side, what is retained from AA 6 and affects recurrent laryngeal nerve path?
Ductus arteriosus (ligamentum arteriosum) - Left recurrent laryngeal nerve loops around it
On the right side, what happens to AA 6 and how does that affect the recurrent laryngeal nerve path?
Distal part regresses away from dorsal aorta and so the right recurrent laryngeal nerve loops around the right subclavian
What happens to the portion of the dorsal aortas between AA 3 and 4?
= carotid duct == obliterated
The right dorsal aorta ____ from 7th intersegmental A. to junction with left dorsal aorta
Disappears
Supplies yolk sac and eventually becomes GI vasculature
Vitelline arteries
Paired ventral branches of dorsal aorta that go to placenta and bladder
Umbilical arteries
Oxygen rich blood bypasses the liver and enters?
IVC and Right atrium
Where does a majority of the blood go once its in the right atrium?
Through the foramen ovale to get to the left atrium
Left atrial blood goes to the left ventricle and then on to the ascending aorta to reach?
Arteries of heart, head, neck, upper limbs
What is special about the blood that reaches the arteries of the heart, head, neck, and upper limbs?
It has the HIGHEST Oxygen content!
Where does some of the blood go once its in the right atrium?
Right ventricle
If blood enters the right ventricle, where does 90% go from there?
To pulmonary trunk – Ductus arteriosus – Descending aorta (bypasses lungs)
Approximately how much blood goes into the lungs?
10%
Ductus arteriosus connects?
Pulmonary trunk with descending aorta to bypass the lungs
Most of the blood in the SVC goes to the?
Right ventricle
Vitelline veins form what in the liver primordia?
Hepatic sinusoids
The right vitelline vein forms?
Right hepatocardiac channel that becomes the inferior IVC
Umbilical veins pass on either side of the?
Liver
Do umbilical veins connect to hepatic sinusoids?
Yes
Which umbilical vein ends up being the only one to carry blood to the liver?
Left umbilical vein
What does the ductus venosus connect?
Left umbilical vein and the right hepatocardiac channel
What drain the body of the embryo?
Cardinal veins
Anastomosis between what form the left brachiocephalic vein?
Right anterior cardinal vein and the Left anterior cardinal vein
When is a common cardinal vein formed?
When the anterior and posterior cardinal veins join
What forms the SVC?
Right common cardinal vein
What does the left cardinal vein form?
Coronary sinus
Proximal right subclavian A is formed from?
AA 4 on the right
Distal right subclavian A is formed from?
7th Cervical Intersegmental A.
What are the 3 main veins in the venous system during development?
Vitelline
Umbilical
Common Cardinal