CPR Autonomics interactive session Flashcards
What is the functional unit of the kidney?
Nephron
Afferent arterioles in the kidney take blood to the?
Glomerulus
Main job of the glomerulus?
Filter the blood and provide raw materials for urine production
Efferent arterioles take blood from glomerulus to ____ capillaries
Peritubular
Peritubular capillaries bring blood from the glomerulus to?
Proximal convoluted tubule
Main job of proximal convoluted tubule?
Reabsorb (back to blood) anything that was filtered that we need and secrete (into urine) anything that did not get filtered that we do not want
From the PCT, vasa recta provide blood to the?
Loop of Henle
Main job of Loop of Henle?
Concentration
From the loop of henle, peritubular capillaries bring blood to the?
Distal Convoluted Tubule
Main job of the Distal convoluted tubule?
Fine tuning of electrolytes and water
The distal convoluted tubule is under what control?
Hormonal and neural (ANS)
Primary innervation to the kidney?
SYMPATHETIC
What type of sympathetic receptors are on kidney arterioles?
Alpha 1 adrenergic
Alpha 1 adrenergic receptors on kidney arterioles do what when stimulated?
Vasoconstriction = decrease blood flow to kidney and decrease urine production
What type of sympathetic receptors are on the kidney juxtaglomerular apparatus?
Beta 1 adrenergic
Beta 1 adrenergic receptors on kidney juxtaglomerular apparatus do what when stimulated?
Increase renin release
– increase sodium and water reabsorption
= increase blood volume to maintain BP
What region of the brain primarily controls the ANS response?
Hypothalamus
For sympathetics, pre-ganglionic fibers synapse where most of the time?
Sympathetic chain
Pre-ganglionic sympathetic fibers release?
Ach - acetylcholine
Pre-ganglionic sympathetic fibers release Ach to what receptors?
Nicotinic (NAchR) on post-ganglionic
Post-ganglionic sympathetic fibers release?
NE - norepinephrine
_____ determines what type of adrenergic receptor NE will bind to from a post-ganglionic sympathetic fiber release
Target tissue
2 actions of sympathetic innervation on the kidney?
- Vasoconstriction - decrease blood flow and urine production
- Renin release - increase Na+ and H20 reabsorption to increase blood volume
What 2 things in the kidney do sympathetics act on?
Arterioles
Juxtaglomerular apparatus
What 2 receptors in the kidney do sympathetics act on?
Alpha 1 adrenergic
Beta 1 adrenergic
Alpha 1 adrenergic receptors are on ___ in the kidney
Arterioles
Beta 1 adrenergic receptors are on _____ in the kidney
Juxtaglomerular apparatus
