POSITIVE SENSE RNA (NAKED) Flashcards by CHESKA CIANNELLE FRANCISCO | Brainscape

Q

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POSITIVE-SENSE

NAKED VIRUSES

A

Calcivirus
Hepevirus
Picornavirus

CHiP

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POSITIVE SENSE | NAKED

Very large virus family
Smallest size
Sensitive to acidic environment
labile, grows at 33C
Virion: icosahedral
Composition: RNA 30%, protein 70%
Replication: cytoplasm
Two major groups of human pathogens
o Enterovirus
o Rhinovirus

A

PICORNA VIRUSES

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

____ virus family

A

very large

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

size

A

smallest

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

virion

A

icosahedral

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

composition

A

RNA 30%
protein 70%

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

replication

A

cytoplasm

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

sensitive to ____ environment

A

acidic

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES

two major groups of human pathogen

A

enterovirus
rhinovirus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PICORNA VIRUSES | ENTEROVIRUS

have a very restricted host range (primates)
Three antigenic types – VP1, VP2, VP3 proteins
Portal of entry – mouth
Site of replication – oropharynx or intestine
Incubation period – 7 to 14 days
Most infections are subclinical

A

POLIOVIRUS

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

under what group of PICORNA virus

A

enterovirus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

have a ____ host range

A

very restricted

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

host range

A

primates

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

three antigenic types

A

VP1
VP2
VP3

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

portal of entry

A

mouth

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

site of replication

A

oropharynx or intestine

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

most infections are ____

A

subclinical

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | TREATMENT & PREVENTION

drugs

A

no antiviral drugs, treatment is symptomatic

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS

incubation period

A

7 - 14 days

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | CLINICAL FINDINGS

decreasing size of muscle due to aging ; not because of the virus

A

Progressive postpoliomyelitis muscle atrophy

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | CLINICAL FINDINGS

fever, malaise, drowsiness, headache, N&V, and sore throat

A

MILD DISEASE (ABORTIVE POLIOMYELITIS)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | CLINICAL FINDINGS

aseptic meningitis

A

nonparalytic poliomyelitis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | CLINICAL FINDINGS

flaccid paralysis resulting from lower motor neuron damage
▪ Memingoencephalitis, meningomyeloencephallitis

A

paralytic poliomyelitis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | TREATMENT & PREVENTION

PREVENTION:
Live attenuated vaccine

A

Sabin vaccine
Oral vaccine, OPV

b - buhay

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

POLIOVIRUS | TREATMENT & PREVENTION

PREVENTION:
Killed vaccine

A

Salk vaccine
Inactivated vaccine, IPV

k - killed

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Coxsackie virus is under what group of PICORNA virus

A

enterovirus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

COXSACKIEVIRUS

originated from what place

A

Coxsackie new york

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

COXSACKIEVIRUS | GROUP A

transmission

A

fecal oral route

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

COXSACKIEVIRUS

Transmission – fecal oral route
Herpangina (types 2 – 6, 8, 10) – severe febrile pharyngitis
Diarrhea in children

A

GROUP A

Q

COXSACKIEVIRUS | GROUP A

severe febrile pharyngitis

A

Herpangina types 2-6, 8, 10

Q

COXSACKIEVIRUS

Pleurodynia
Myocarditis and pericarditis (types 1 – 5)
Generalized disease of infants (types 1 – 5)

A

GROUP B

Q

COXSACKIEVIRUS | GROUP A

diseases

A

Herpangina
Diarrhea in children

Q

A

Q

COXSACKIEVIRUS | GROUP A

disease in children

A

diarrhea

Q

A

Q

A

Q

A

Q

COXSACKIEVIRUS

can cause flaccid paralysis
Aseptic meningitis
Hand-foot-and-mouth disease

A

GROUP A & B

Q

COXSACKIEVIRUS | GROUP A & B

hand, foot and mouth disease

A

types A5, 10, 160

Q

COXSACKIEVIRUS | GROUP B

MYOCARDITIS & PERICARDITIS

A

types 1 - 5

Q

COXSACKIEVIRUS | GROUP B

characterized by simultaneous viral infections of multiple organs, including the heart, liver, and brain

A

generalized disease of infants

Q

COXSACKIEVIRUS | GROUP A & B

aseptic meningitis

A

types A7 & A9; type B

Q

COXSACKIEVIRUS | GROUP B

generalized disease of infants

A

types 1 - 5

Q

COXSACKIEVIRUS | GROUP A & B

characterized by fever, malaise, headache, nausea, and abdominal pain

A

aseptic meningits

Q

PICORNA VIRUS | ENTEROVIRUS

Enteric Cytopathogenic Human Orphan Viruses
Transmission – fecal oral
Diseases – aseptic meningitis, encephalitis, febrile illness with or without rash, common colds, ocular disease

A

ECHOVIRUS

Q

COXSACKIEVIRUS | GROUP A & B

characterized by oral and pharyngeal ulcerations and a vesicular rash of the palms and soles

A

hand, foot, and mouth disease

Q

ECHOVIRUS

is under what group of PICORNA virus

A

enterovirus

Q

ECHOVIRUS

meaning of ECHO

A

Enteric Cytopathogenic Human Orphan Viruses

Q

OTHER ECHOVIRUS

acute hemorrhagic conjunctivitis

A

ENTEROVIRUS 70

Q

ECHOVIRUS

transmission

A

fecal oral

Q

OTHER ECHOVIRUS

meningitis, encephalitis, and paralysis resembling poliomyelitis, hand-foot-and-mouth disease

A

ENTEROVIRUS 71

Q

OTHER ECHOVIRUS

Hepatitis A virus

A

ENTEROVIRUS 72

Q

ECHOVIRUS

leading cause of ____

A

aseptic meningitis

Q

RHINOVIRUS

____ labile

A

acid

Q

PICORNA VIRUS

Common cold virus
Acid-labile
Temperature requirement: 33C
Transmission – sneezing, hand-to-hand, hand-to-eye, or hand-to-object-to-hand
The virus enters via URT, and replicates in the nasal mucosa
Incubation – 2 to 4 days
Usual symptoms in adults – sneezing, nasal obstruction, nasal discharge, and sore throat
Other symptoms – headache, mild cough, malaise, and a chilly sensation
Other viruses causing URT infections – coronavirus, adenovirus, enterovirus, parainfluenza virus, influenza virus

A

RHINOVIRUS

Q

RHINOVIRUS

portal of entry

A

URT

Q

RHINOVIRUS

____ virus

A

common cold

Q

RHINOVIRUS

temperature requirement

A

33C

Q

RHINOVIRUS

replication site

A

nasal mucosa

Q

RHINOVIRUS

Usual symptoms in adults

A

sneezing
nasal obstruction
nasal discharge
sore throat

Q

RHINOVIRUS

incubation

A

2 - 4 days

Q

RHINOVIRUS

other symptoms

A

headache
mild cough
malaise
chilly sensation

Q

CALCIVIRUS

Norovirus ____ communicable

A

highly

Q

A

Q

RHINOVIRUS

other viruses causing URT infections

A

corona
adeno
enetero
parainfluenza
influenza

Q

A

Q

PICORNA VIRUS

Norovirus
Sapovirus
Nebovirus
Lagovirus
Vesivirus

A

CALCIVIRUS

Q

CALCIVIRUS

NOROVIRUS:
infectious dose

A

10 viral particles

Q

CALCIVIRUS

Sapporo-like virus

A

Sapovirus

Q

CALCIVIRUS

Bovine enteric virus

A

Nebovirus

Q

CALCIVIRUS

rabbit hemorrhagic disease virus

A

Lagovirus

Q

CALCIVIRUS

vesicular exanthem virus

A

Vesivirus