Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MICROPARA > M7 DNA VIRUS | NAKED > Flashcards

M7 DNA VIRUS | NAKED Flashcards

1
Q

DNA NAKED viruses

A

Adenovirus
Papillomavirus
Polyomavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

symmetry of ALL naked DNA viruses

A

icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

NAKED

  • only virus that has fibers
  • Virion – icosahedral, 70-90 nm in diameter, 252 capsomeres; fiber projects from each vertex
  • Composition – DNA (13%), protein (87%)
  • Genome – double-stranded DNA, linear, 26-45 kbp, protein bound to termini, infectious
  • Proteins – important antigens (hexon, penton base, fiber) are associated with the major outer capsid proteins
  • Envelope – none
  • Replication – nucleus
  • Outstanding characteristic – excellent models for molecular studies of eukaryotic cell processes
A

ADENOVIRUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ADENOVIRUS

VIRION:
symmetry

A

icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ADENOVIRUS

VIRION:
size

A

70-90nm diameter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ADENOVIRUS

VIRION:
capsomeres

A

252

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ADENOVIRUS

composition

A

DNA 13%
protein 87%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ADENOVIRUS

PROTEINS:
important antigens

A

hexon, penton base, fiber

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ADENOVIRUS

important antigens (hexon, penton base, fiber) are associated with the ____

A

major outer capsid proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ADENOVIRUS

replication

A

nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ADENOVIRUS

excellent models for molecular studies of ____

A

eukaryotic cell processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

ADENOVIRUS

isolated in the ____

A

adenoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ADENOVIRUS

GROUP C

A

1, 2, 5, 6, 57,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ADENOVIRUS

can establish latent infection in adenoid tissue & tonsils

A

GROUP C
1, 2, 5, 6, 57

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ADENOVIRUS

GROUP C can establish latent infections in

A

adenoid tissue & tonsils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
Acute RTI in young children

A

types 1, 2, 5, 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
Acute RTI in adolescents and adults

A

types 3, 4, 7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

ADENOVIRUS | CLINICAL FINDINGS

respiratory diseases can lead to

A

pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
10 to 20% childhood pneumonia

A

types 3, 7, 21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
____ to ____% childhood pneumonia

A

10 to 20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
Outbreak of severe respiratory disease in 2007 (all ages)

A

type 14

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
Acute respiratory disease syndrome among military recruits

A

types 3, 4, 7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

ADENOVIRUS | CLINICAL FINDINGS

RESPIRATORY DISEASE:
among military recruits

A

acute respiratory disease syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

ADENOVIRUS | CLINICAL FINDINGS

DISEASES

A

respiratory
eye
GI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

ADENOVIRUS | CLINICAL FINDINGS | EYE INFECTIONS

Mild ocular involvement maybe part of the ____

A

RESPIRATORY PHARYNGEAL SYNDROMES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

ADENOVIRUS | CLINICAL FINDINGS | EYE INFECTIONS

“Swimming pool conjunctivitis” in children

A

types 3, 7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

ADENOVIRUS | CLINICAL FINDINGS | EYE INFECTIONS

Epidemic and highly contagious keratoconjunctivitis in adults

A

types 8, 9, 37

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

ADENOVIRUS | CLINICAL FINDINGS

Brought about by the replication of the virus in the intestinal cells and their presence in stools

A

GASTROINTESTINAL DISEASES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

ADENOVIRUS | CLINICAL FINDINGS | GASTROINTESTINAL DISEASES

a viral gastroenteritis in young children manifested as diarrhea

A

INFANTILE GASTROENTERITIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

ADENOVIRUS | CLINICAL FINDINGS | GASTROINTESTINAL DISEASES

“Infantile gastroenteritis” a viral gastroenteritis in young children manifested as diarrhea

A

type 40, 41

31
Q

ADENOVIRUS | CLINICAL FINDINGS | OTHER DISEASES (IMMUNOCOMPROMISED)

Respiratory disease that progresses to severe and fatal pneumonia among transplant patients

A

types 1 - 7

32
Q

ADENOVIRUS | CLINICAL FINDINGS | OTHER DISEASES (IMMUNOCOMPROMISED)

in children
kidney & bone marrow transplant patients

A

acute hemorrhagic cystitis

33
Q

ADENOVIRUS | TREATMENT

DOC

A

no specific treatment

34
Q

ADENOVIRUS | TREATMENT

Live adenovirus vaccine

A

types 4, 7

35
Q

ADENOVIRUS | TREATMENT

  • administered orally as a capsule
  • reserved for military
A

Live adenovirus vaccine

36
Q

NAKED

  • Small viruses with circular genome
  • It contains genes that code for T (tumor) antigen, inhibiting p53 and Rb
A

HUMAN POLYOMA VIRUS

37
Q

HUMAN POLYOMA VIRUS

small viruses with ____ genome

A

circular

38
Q

HUMAN POLYOMA VIRUS

it contains genes that code for ____ antigen, inhibiting p53 and Rb

A

T (tumor)

39
Q

HUMAN POLYOMA VIRUS

p53 and Rb are

A

tumor suppressor gene

40
Q

HUMAN POLYOMA VIRUS

  • kidney
  • causes hemorrhagic cystitis and polyomavirus-associated nephropathy
  • among transplant patients
A

BK virus

41
Q

HUMAN POLYOMA VIRUS

  • brain
  • causes progressive multifocal leukoencephalopathy
A

JC virus

42
Q

HUMAN POLYOMA VIRUS

  • occurred in nasopharyngeal aspirates in children with respiratory infections
  • patients with existing respiratory infections
A

KI and WU viruses

43
Q

HUMAN POLYOMA VIRUS

  • face, neck
  • associated with Merkel-cell carcinoma, a rare skin tumor of neuroendocrine origin
  • aggressive
A

MERKEL CELL virus

44
Q

HUMAN POLYOMA VIRUS

  • transmission by close contact;
  • carcinogenesis involves synthesis of viral proteins E6 and E7 that interfere with the activity, p53 and Rb
A

WARTS virus

45
Q

HUMAN POLYOMA VIRUS | WARTS VIRUS

transmission by

A

CLOSE CONTACT

46
Q

HUMAN POLYOMA VIRUS | WARTS VIRUS

____ involves synthesis of viral proteins E6 and E7 that interfere with the activity, p53 and Rb

A

CARCINOGENESIS

47
Q

HUMAN POLYOMA VIRUS | WARTS VIRUS

carcinogenesis involves synthesis of viral proteins ____ and ____ that interfere with the activity, p53 and Rb

A

E6, E7

48
Q

HUMAN POLYOMA VIRUS | PREVENTION & CONTROL

for cervical cancer

early detection

A

Papanicolaou (Pap) smear

49
Q

HUMAN POLYOMA VIRUS | PREVENTION & CONTROL

vaccine

A

HPV vaccine
GARDASIL 9

also associated w/ oral pharyngeal cancer

50
Q

HUMAN POLYOMA VIRUS | TYPE

recurrent respiratory papillomatis

A

type 6, 11

51
Q

HUMAN POLYOMA VIRUS | TYPE

responsible for cervical cancer

A

type 16, 18

52
Q

NAKED

  • the ONLY single stranded DNA virus
  • Smallest DNA animal viruses
  • Transmission – respiratory route, blood transfusions, and vertically
A

PARVOVIRUS

53
Q

PARVOVIRUS

the only ____ DNA virus

A

single stranded

54
Q

PARVOVIRUS

  • pathogenic for humans and has a tropism for erythroid progenitor cells
  • targets EPC where RBC forms
A

PARVOVIRUS B19

55
Q

PARVOVIRUS

transmission

A

respiratory
blood
vertically

56
Q

PARVOVIRUS

replication

A

nucleus

57
Q

PARVOVIRUS

targets mainly ____

A

RBC production

58
Q

PARVOVIRUS | HUMAN DISEASES

  • HOST: Children (Fifth disease), Adults
  • CLINICAL FEATURE: cutaneous rash (slapped cheeck syndrome), arthralgia – arthirits
A

ERYTHEMA INFECTIOSUM

59
Q

PARVOVIRUS | HUMAN DISEASES

also known as Fifth disease

A

Erythema infectiosum

60
Q

PARVOVIRUS | HUMAN DISEASES

cutaneous rash in erythema infectiosum is also known as

A

slapped cheek syndrome

61
Q

PARVOVIRUS | HUMAN DISEASES

  • CONDITION: underlying hemolysis
  • CLINICAL FEATURE: severe acute anemia
  • stops the synthesis of RBC
A

TRANSIENT APLASTIC CRISIS

62
Q

PARVOVIRUS | HUMAN DISEASES

  • CONDITION: immunodeficiencies
  • CLINICAL FEATURE: chronic anemia
A

PURE RED CELL APLASIA

63
Q

PARVOVIRUS | HUMAN DISEASES

  • HOST: fetus
  • CLINICAL FEATURE: fatal anemia
A

HYDROPS FETALIS

64
Q

PARVOVIRUS | HUMAN DISEASES

  • Fifth disease – “Slapped Cheek Syndrome”
  • Characterized by fever and bright red rash on the cheeks
  • A lace-like rash on the body may appear on the body (in adults)
  • It mimics rheumatoid arthritis in adults
  • Symptomatic treatment
A

ERYTHEMA INFECTIOSUM

65
Q

PARVOVIRUS | HUMAN DISEASES | ERYTHEMA INFECTIOSUM

a rash that may appear on the body of adults

A

lace like rash

66
Q

PARVOVIRUS | HUMAN DISEASES | ERYTHEMA INFECTIOSUM

it mimics ____ in adults

A

rheumatoid arthritis

67
Q

PARVOVIRUS | HUMAN DISEASES | ERYTHEMA INFECTIOSUM

treatment

A

symptomatic

68
Q

PARVOVIRUS | HUMAN DISEASES

  • The syndrome is an abrupt cessation of RBC synthesis in the bone marrow
  • sudden stop of RBC synthesis
  • Individuals with chronic hemolytic anemia, such as patients with sickle cell disease, thalassemia, and acquired hemolytic anemias in adults are susceptible (only with patients with exisiting condition)
  • Symptomatic treatment
A

TRANSIENT APLASTIC CRISIS

69
Q

PARVOVIRUS | HUMAN DISEASES | TRANSIENT APLASTIC CRISIS

The syndrome is an abrupt ____ in the bone marrow

A

CESSATION OF RBC SYNTHESIS

70
Q

PARVOVIRUS | HUMAN DISEASES | TRANSIENT APLASTIC CRISIS

The syndrome is an abrupt cessation of RBC synthesis in ____

A

BONE MARROW

71
Q

PARVOVIRUS | HUMAN DISEASES | TRANSIENT APLASTIC CRISIS

treatment

A

symptomatic

72
Q

PARVOVIRUS | HUMAN DISEASES

  • Pure red cell aplasia
  • It has been observed in patient populations with congenital immunodeficiency, malignancies, AIDS, and organ transplantation
A

B19 INFECTION IN IMMUNODEFICIENT PATIENTS

73
Q

PARVOVIRUS | HUMAN DISEASES | B19 INFECTION IN IMMUNODEFICIENT

it is characterized by chronic suppression of bone marrow

A

PURE RED CELL APLASIA

74
Q

PARVOVIRUS | HUMAN DISEASES | B19 INFECTION DURING PREGNANCY

1st trimester

A

fetal death due to severe anemia

75
Q

PARVOVIRUS | HUMAN DISEASES | B19 INFECTION DURING PREGNANCY

  • 2nd trimester
  • swelling of organs
A

hydrops fetalis

76
Q

PARVOVIRUS

Parvovirus B19 is pathogenic for humans and has a tropism for ____

A

erytheroid progenitor cells

MICROPARA (37 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions