HEPATITIS

Question 1

HEPATITIS

Viral hepatitis is a ____ primarily involving the liver

Answer 1

SYSTEMIC DISEASE

Question 2

HEPATITIS

Viral hepatitis is a systemic disease primarily involving the ____

Answer 2

LIVER

Question 3

HEPATITIS

classic feature of hepatitis

Answer 3

jaundice

Question 4

HEPATITIS

yellow discoloration of the skin and eyes

Answer 4

JAUNDICE

Question 5

HEPATITIS

hepatitis viruses

Answer 5

A B C D E

Question 6

HEPATITIS VIRUSES

single stranded RNA

Answer 6

A C D E

Question 7

HEPATITIS VIRUSES

the only double stranded and DNA virus

Answer 7

HEPA B

Question 8

HEPATITIS VIRUSES

• the family is unclassified;
• an example of defective virus that cannot replicate on its own;
• requires the presence of hepatitis B for its replication, either from a previous history or hepatitis B infection or coinfection of these two viruses

Answer 8

hepa D

Question 9

HEPATITIS VIRUSES

main hepa viruses

Answer 9

A B C

Question 10

HEPATITIS VIRUSES

MODE OF TRANSMISSION:
Hepa A & E

Answer 10

fecal oral route

FAECAL

Question 11

HEPATITIS VIRUSES

MODE OF TRANSMISSION:
Hepa B, C, D

Answer 11

parenteral

blood transfusion, needlestick, sexual, vertical

Question 12

HEPATITIS VIRUSES

• acute form of hepatitis
• The onset of disease is abrupt within 24 hours.
• Frequently seen in children; may be severe with adults

Answer 12

HEPA A

Question 13

HEPATITIS A

____ form hepatitis

Answer 13

acute

Question 14

HEPATITIS A

onset of disease

Answer 14

abrupt; within 24 hrs

Question 15

onset of disease of hepa B & C

Answer 15

lower

Question 16

HEPATITIS A

frequently seen in

Answer 16

children

Question 17

HEPATITIS A

severe with

Answer 17

adults

Question 18

HEPATITIS A | PREVENTION

active immunity

Answer 18

inactivated HAV vaccine

Question 19

HEPATITIS A | PREVENTION

passive immunity

Answer 19

immuneglobulin IG

Question 20

HEPATITIS A | PREVENTION

for areas endemic with hepatitis

Answer 20

pre-exposure & post-exposure prophylaxis

Question 21

HEPATITIS A | PREVENTION

____ are effective as post-exposure prophylaxis two weeks of exposure

Answer 21

vaccines

Question 22

HEPATITIS A | PREVENTION

passive immunization is effective within ____ after exposure to prevent & mitigate Hepa A

Answer 22

14 days

Question 23

HEPATITIS VIRUSES

• Inapparent infections
• Infants and young children become chronic carriers
• Chronic carriers are at risk of developing hepatocellular carcinoma
• Fulminant hepatitis with HDV
• Fulminant – severe and sudden onset, may happen is there is coinfection with hepatitis D
• Most chronic carriers are asymptomatic, but some may have chronic active hepatitis, leading to cirrhosis and death

Answer 23

HEPA B

Question 24

HEAPTITIS B

____ infection

Answer 24

inapparent

Question 25

# **HEPATITIS B** **infants** and **young children** become ____

Answer 25

chronic carriers

Question 26

# **HEPATITIS B** **chronic carriers** are at risk of developing | (liver cancer)

Answer 26

hepatocellular carcinoma

Question 27

# **HEPATITIS B** ____ hepatitis with **HDV**

Answer 27

fulminant

Question 28

# **HEPATITIS B** **severe** and **sudden onset**, may happen is there is **coinfection** with hepatitis **D**

Answer 28

fulminant

Question 29

# **HEPATITIS B** **most** chronic carriers are ____

Answer 29

asymptomatic

Question 30

# **HEPATITIS B** symptoms are usually ____ with hepa **A**

Answer 30

same

Question 31

# **HEPATITIS B** symptoms are ____ than Hepa **A**

Answer 31

more severe

Question 32

# **HEPATITIS B** antigens & antibodies

Answer 32

surface envelope core

Question 33

# **HEPATITIS B** describes the **virion** for **envelope antigen**

Answer 33

dane particle

Question 34

# **HEPATITIS B** **antigen** that is **not measured**

Answer 34

core antigen

Question 35

# **HEPATITIS B** 2 types of **core antibody**

Answer 35

total anti-HBc IgM anti-HBc

Question 36

# **HEPATITIS B | SEROLOGY MARKERS** * **Surface antigen** for Hepa B * **Indicates infection** * used in **vaccine production**

Answer 36

HbsAg

Question 37

# **HEPATITIS B | SEROLOGY MARKERS** * **Antibody** for **surface** antigen * Implies a **certain state of immunity** - **recovery** from previous infection - from **vaccines**

Answer 37

anti-HBsAg

Question 38

# **HEPATITIS B | SEROLOGY MARKERS** **exposure** to **surface antigen** results to the **production** of

Answer 38

antibody

Question 39

# **HEPATITIS B | SEROLOGY MARKERS** * **Total antibody** to Hepa B **core** antigen * appears as the **symptom** for **acute** form * **measure** both **IgM** and **IgG**

Answer 39

total anti-HbcAg

Question 40

# **HEPATITIS B | SEROLOGY MARKERS** **indicates** a **previous** or **ongoing** infection with hepa B

Answer 40

core antigen

Question 41

# **HEPATITIS B | SEROLOGY MARKERS** previous infection

Answer 41

IgG

Question 42

# **HEPATITIS B | SEROLOGY MARKERS** **ongoing** infection

Answer 42

IgM

Question 43

# **HEPATITIS B | SEROLOGY MARKERS** * **IgM antibody** to Hepa B core antigen * Immunoglobulin produced in response to **acute infection** * indicates **recent** infection or **ongoing** infection **less than 6 months**

Answer 43

IgM anti-HBcAg

Question 44

# **HEPATITIS B | TREATMENT** First line

Answer 44

Pegylatedinterferonalfa-2a entecavir tenofovir

Question 45

# **HEPATITIS B | PREVENTION** **pre**-exposure prophylaxis

Answer 45

Hepa B vaccine

Question 46

# **HEPATITIS B | PREVENTION** **post**-exposure prophylaxis not recommend as pre-exposure prohylaxis because there is vaccine

Answer 46

Hepa B immune globulin (HBIG)

Question 47

# **HEPATITIS VIRUSES** * Clinically **mild**, with **moderate elevation** of **liver enzymes** * May progress to **chronic** liver disease * Many patients develop **cirrhosis** → hepatocellularcarcinoma * **End-stage** liver disease associated with **HCV** is the most frequent indication for **adult liver transplants**

Answer 47

HEPA C

Question 48

# **HEPATITIS VIRUSES | HEPATITIS C** Clinically mild with ____ of **liver enzymes**

Answer 48

moderate elevation

Question 49

# **HEPATITIS VIRUSES | HEPATITIS C** **liver enzymes** that are being elevated

Answer 49

alanine transaminase (ALT) aspartate transaminase (AST)

Question 50

# **HEPATITIS VIRUSES | HEPATITIS C** may progress to ____

Answer 50

chronic liver disease

Question 51

# **HEPATITIS VIRUSES | HEPATITIS C** many patients develop ___ that leads to **hepatocellular carcinoma**

Answer 51

cirrhosis

Question 52

# **HEPATITIS VIRUSES | HEPATITIS C** **End-stage liver disease associated with HCV** is the most frequent indication for

Answer 52

adult liver transplants

Question 53

# **HEPATITIS C** TREATMENT: standard treatment for **chronic** hepatitis C

Answer 53

pegylated interferon combined w/ ribavirin