ARTHROPOD & RODENT BORNE Flashcards

1
Q
  • transmitted by bloodsucking arthropods from one vertebrate host to another
  • multiply in the tissues of arthropods without causing a disease/damage but establish life long infection
A

ARBOVIRUS

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2
Q

ARBOVIRUS

transmitted by ____ arhtropods

A

bloodsucking

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3
Q
  • transmission from rodent to rodent without participation of arthropod vectors
  • contact with body fluids or excretion
A

ROBOVIRUS

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4
Q
  • Fevers of an undifferentiated type with or without a maculopapular rash and usually benign
  • Encephalitis
  • Hemorrhagic fevers
A

ARBOVIRUS

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5
Q

ARBOVIRUS

disease is observed only in

A

humans

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6
Q

ARBOVIRUS

humans are considered as

A

dead end host

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7
Q

ARBOVIRUS

only ____ serve as vectors

A

females

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8
Q

ARBOVIRUS

____ is also possible
mother tick to baby tick

A

transovarian transmission

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9
Q

ARBOVIRUS CAUSING ENCEPHALITIS

Family: Togavirus
Vector: Culex mosquito

A

EASTERN & WESTERN EQUINE ENCEPHALITIS

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10
Q

ARBOVIRUS CAUSING ENCEPHALITIS

  • most severe causing encephalitis with high case of fatality
  • seen in rural areas
A

Eastern encephalitis

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11
Q

ARBOVIRUS CAUSING ENCEPHALITIS

  • more prominent in urban areas
  • moderately severe encephalitis
A

St. Louis

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12
Q

ARBOVIRUS CAUSING ENCEPHALITIS

common cause of encephalitis and meningitis in US in ages over 60 years old

A

West Nile

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13
Q

ARBOVIRUS CAUSING ENCEPHALITIS

leading cause of viral encephalitis

A

Japanese B

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14
Q

ARBOVIRUS CAUSING ENCEPHALITIS

Family: Flavivirus
Vector: Ixodes tick

A

Tick-borne

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15
Q

ARBOVIRUS CAUSING ENCEPHALITIS

Family: Bunyavirus
Vector: Aedes mosquito

A

California

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16
Q

ARBOVIRUS CAUSING ENCEPHALITIS

most important type of California encephalitis

A

La Crosse virus

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17
Q

ARBOVIRUS

  • From Flavivirus
  • Vector – Aedes mosquito
  • characterized by fever and jaundice
  • May range from mild to severe form of disease
  • Two distinct cycles
A

YELLOW FEVER

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18
Q

ARBOVIRUS | YELLOW FEVER

family

A

Flavivirus

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19
Q

ARBOVIRUS | YELLOW FEVER

vector

A

aedes mosquito

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20
Q

ARBOVIRUS | YELLOW FEVER

characterized by

A

fever & jaundice

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21
Q

ARBOVIRUS | YELLOW FEVER

may range from ____ form of disease

A

mild to severe

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22
Q

ARBOVIRUS | YELLOW FEVER

disease of the monkeys

A

jungle yellow fever

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23
Q

ARBOVIRUS | YELLOW FEVER

disease of humans

A

urban yellow fever

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24
Q

ARBOVIRUS | YELLOW FEVER

PREVENTION

A

live attenuated yellow fever virus vaccine

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25
Q

ARBOVIRUS | DENGUE VIRUS

family

A

flavivirus

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26
Q

ARBOVIRUS | DENGUE VIRUS

vector

A

aedes mosquito

27
Q

ARBOVIRUS | DENGUE VIRUS

  • self limiting
  • Onset of fever (2 – 7 days), malaise, chills, and HA
  • fever may subside on the 3rd day and may rise again
  • Pain in the back joints (deep bone pain), muscles (myalgia), and eyeballs
  • Rashes may appear on the 3rd day
  • Lymph nodes are enlarged
A

classing dengue fever (breakbone fever)

28
Q

ARBOVIRUS | DENGUE VIRUS

classic dengue fever is also called

A

breakbone fever

29
Q

ARBOVIRUS | DENGUE VIRUS

reservoir

A

humans

30
Q

ARBOVIRUS | DENGUE VIRUS

how many serotypes

A

4

31
Q

ARBOVIRUS

most common insect borne disease in the world

A

dengue fever

32
Q

ARBOVIRUS | DENGUE VIRUS

classic chaarcteristics of dengue

A

pain in bakc joints, muscles, eyeballs

33
Q

ARBOVIRUS | DENGUE VIRUS

  • Dengue shock syndrome
  • Initial symptoms resemble classic dengue (shock)
  • infected initially with 1st serotype; patient survived
  • becomes infected again by the 2nd serotype, occurence of cross activity resulting to hemorrhage and may lead to shock if not addressed
A

Dengue hemorrhagic fever

34
Q

ARBOVIRUSES CAUSING FEVER

  • Family: Togavirus
  • Vector: Aedes
  • resembles dengue
  • more likely to cause fever, rashes and severe joint pain
A

CHIKUNGUNYA

35
Q

ARBOVIRUSES CAUSING FEVER

  • Family: Flavivirus
  • Vector: Aedes
  • presentation is similar to dengue
  • can be transmitted vertically from mother to fetus
  • affect other organs (brain)
  • fetal abnormalities may arise in 1st trimester (microcephaly)
A

ZIKA VIRUS

36
Q

ARBOVIRUSES CAUSING FEVER

Family: Bunyavirus
Vector: Phlebotomus sandfly

A

Sandfly fever virus

36
Q

ARBOVIRUSES CAUSING FEVER

  • Family: Bunyavirus
  • Vector: Phlebotomus sandfly
  • mild febrile illness
A

Rift valley fever

37
Q

ARBOVIRUSES CAUSING FEVER

  • Family: Reovirus (Coltivirus)
  • Vectors: Dermacentor tick
  • common in hikers/campers in rocky mountains
  • fever is diphasic (after 2 days patient will feel better; symptoms will reappear that may last 3-4 weeks)
A

Colorado tick fever

38
Q

ARBOVIRUSES CAUSING FEVER

Colorado tick fever is also called as

A

mountain fever

39
Q

ROBOVIRUSES

  • Genus Hantavirus
  • Hemorrhagic fever with renal syndrome (HFRS)
  • Hantavirus Pulmonary Syndrome (HPS)
A

BUNYAVIRUSES

40
Q

ROBOVIRUSES | BUNYAVIRUS

genus

A

hantavirus

41
Q

ROBOVIRUSES | BUNYAVIRUS

  • an acute infection causing interstitial nephritis that can lead to acute renal insufficiency and generalized hemorrhage and shock
  • Transmitted by urban rats
  • Viruses includes
    Hantaan virus and Dobrava virus (Asia and Europe)
    Seoul virus (Eurasia)
A

hemorrhagic fever with renal syndrome (HFRS)

42
Q

ROBOVIRUSES | BUNYAVIRUS | HEMORRHAGIC WITH RENAL

transmitted by

A

urban rats

43
Q

ROBOVIRUSES | BUNYAVIRUS | HEMORRHAGIC WITH RENAL

causes

A

interstitial nephritis

44
Q

ROBOVIRUSES | BUNYAVIRUS | HEMORRHAGIC WITH RENAL

interstitial nephritis can lead to

A

acute renal insufficiency & generalized hemorrhage and shock

45
Q

ROBOVIRUSES | BUNYAVIRUS | HEMORRHAGIC WITH RENAL

VIRUSES CAUSING HFRS:
Asia & Europe

A

Hantaan virus & Dobrava virus

46
Q

ROBOVIRUSES | BUNYAVIRUS | HEMORRHAGIC WITH RENAL

VIRUS CAUSING HFRS:
Eurasia

A

Seoul virus

47
Q

ROBOVIRUSES | BUNYAVIRUS

  • begins with fever, HA, and myalgia followed by rapidly progressing pulmonary edema that leads to a severe respiratory compromise
  • Sin Nombre virus (North America) whose rodent reservoir is the deer mouse
  • New York virus, Black Creek Canal virus, Bayou virus in **US
  • Andes virus in Argentina and Chile
  • Choclo virus in Panama
A

hantavirus pulmonary syndrome

48
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

clinical manifestation

A

pulmonary edema

49
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

pulmonary edema leads to a

A

severe respiratory compromise

50
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

North america
Rodent: deer mouse

A

Sin Nombre virus

51
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

Sin Nombre virus rodent

A

deer mouse

52
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

viruses in US

A

New york
Black creek canal
Bayou

53
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

Argentina and Chile

A

Andes virus

54
Q

ROBOVIRUSES | BUNYAVIRUS | HANTAVIRUS PULMONARY SYNDROME

Panama

A

Choclo

55
Q

ROBOVIRUSES

  • name means SAND - describes the presence of granules (nonfunctional ribosomes) in cytoplasm of the virion
  • Pleomorphic particles with segmented RNA genome (negative); are surrounded by an envelope
  • Lassa fever virus
  • Lymphocytic Choriomeningitis Virus (LCM)
A

ARENAVIRUS

56
Q

ROBOVIRUSES | ARENAVIRUS

the granules present in the cytoplasm of the virion are

A

nonfunctional ribosomes

57
Q

ROBOVIRUSES | ARENAVIRUS

The disease is characterized by very high fever, mouth ulcers, severe muscle aches, skin rash with hemorrhages, pneumonia, and heart and kidney damage

A

Lassa fever virus

58
Q

ROBOVIRUSES | ARENAVIRUS

Lassa fever virus DOC

A

ribavirin

59
Q

ROBOVIRUSES | ARENAVIRUS

  • Transmitted to humans via mouse droppings
  • May cause aseptic meningitis or a mild systemic influenza-like illness
  • can be transmitted vertically
A

Lymphocytic Choriomeningits Virus (LCM)

60
Q

ROBOVIRUSES | ARENAVIRUS | LYMPHOCYTIC

transmitted via

A

mouse droppings

61
Q

ROBOVIRUSES | ARENAVIRUS | LYMPHOCYTIC

  • rare case
  • cannot be distinguished from the more frequent viral causes of the disease
A

aseptic meningitis

62
Q

ROBOVIRUSES | ARENAVIRUS | LYMPHOCYTIC

may be serious in people with impaired immune system

A

mild systemic influenza like illness