PARASITOLOGY Flashcards
one in which the sexual cycle occurs or the adult is present
DEFINITIVE HOST
one in which the asexual cycle occurs or the larva is present.
INTERMEDIATE HOST
In some helminthic infections, humans are ____
DEAD END HOSTS
the larval form in the human is not transmitted to other humans or animals
DEAD END HOST
actively motile, feeding, reproducing form
TROPHOZITE
nonmotile, nonmetabolizing, nonreproducing form surrounded by a thick wall.
CYST
cyst turns into ____ after entering the host
trophozite
seen in the environment
cyst
Certain protozoa, such as Leishmania and Trypanosoma, have flagellated forms called ____ or ____
promastigotes or trypomastigotes
non-flagellated forms
amastigotes
Transmission of the intestinal protozoa typically occurs by
ingestion of cysts
from contaminated water or food
Transmission of the blood protozoa occurs via
insect vectors
INTESTINAL PROTOZOA
- The cyst has four nuclei, an important diagnostic criterion.
- Cysts (ingested form) → Within the intestine → produces trophozoites
- Clinical findings:
o **Amebic dysentery **
o Amebic abscess of the liver
ENTAMOEBA HISTOLYTICA
INTESTINAL PROTOZOA | ENTAMOEBA HISTOLYTICA
cyst has how many nuclei
4
INTESTINAL PROTOZOA | ENTAMOEBA HISTOLYTICA
important diagnostic criterion
cyst w/ 4 nuclei
INTESTINAL PROTOZOA | ENTAMOEBA HISTOLYTICA
diarrhea, bloody stool, intestinal tract
amebic dysentry
INTESTINAL PROTOZOA | ENTAMOEBA HISTOLYTICA
has pus that contains trophozites
amebic abscess of the liver
INTESTINAL PROTOZOA | ENTAMOEBA HISTOLYTICA
DOC
metronidazole (Flagyl)
tinidazole
INTESTINAL PROTOZOA
- “Old man’s eyeglasses”
- Clinical findings:
o Watery (nonbloody), foul-smelling diarrhea
o Trophozoite causes inflammation of the duodenal mucosa, leading to malabsorption of protein and fat.
GIARDIA LAMBLIA
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
other name
old man’s eyeglasses
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
foul-smelling diarrhea can produce ____
(rotten egg odor)
H2S
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
excessive fat in feces
steatorrhea
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
Trophozoite causes inflammation of the duodenal mucosa, leading to malabsorption of ____ and ____
protein & fat
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
Trophozoite causes inflammation of the ____, leading to malabsorption of protein and fat
duodenal mucosa
INTESTINAL PROTOZOA | GIARDIA LAMBLIA
DOC
Tinidazole (Tindamax)
Metronidazole (Flagyl)
INTESTINAL PROTOZOA
- Oocysts ingestion
- Cryptosporidiosis, the main symptom of which is diarrhea.
- The diarrhea is most severe in immunocompromised patients (e.g., those with acquired immunodeficiency syndrome [AIDS]).
CRYPTOSPORIDIUM HOMINIS
INTESTINAL PROTOZOA | CRYPTOSPORIDIUM HOMINIS
cyst with zygote
oocyst
INTESTINAL PROTOZOA | CRYPTOSPORIDIUM HOMINIS
disease
cryptosporidiosis
INTESTINAL PROTOZOA | CRYPTOSPORIDIUM HOMINIS
main symptom of cryptosporidiosis
diarrhea
INTESTINAL PROTOZOA | CRYPTOSPORIDIUM HOMINIS
diarrhea is most severe in
immunocompromised
INTESTINAL PROTOZOA | CRYPTOSPORIDIUM HOMINIS
DOC
nitazoxanide
UROGENITAL PROTOZOA
- Only exists as a trophozoite
- Sexually transmitted
- Women, - watery, foul-smelling, greenish vaginal discharge accompanied by itching and burning occurs.
- Men - asymptomatic, but about 10% of infected men have urethritis.
TRICHOMONAS VAGINALIS
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
DISEASE
TRICHOMONIASIS
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
exist as
only as trophozoite
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
symptoms in women
watery, foul smelling, greenish vaginal discharge w itching & burning
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
symptoms in men
asymptomatic
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
about 10% of infected men have ____
urethritis
UROGENITAL PROTOZOA | TRICHOMONAS VAGINALIS
DOC
TINIDAZOLE
METRONIDAZOLE
BLOOD & TISSUE PROTOZOA
- Malaria
- Vector: female anopheles mosquito
plasmodium
BLOOD & TISSUE PROTOZOA | PLASMODIUM
DISEASE
MALARIA
BLOOD & TISSUE PROTOZOA | PLASMODIUM
malaria is caused by how many plasmodia
4
BLOOD & TISSUE PROTOZOA | PLASMODIUM
4 plasmodia that causes malaria
vivax
ovale
malariae
falciparum
BLOOD & TISSUE PROTOZOA | PLASMODIUM
can form dormant in LIVER are called
hypnozoite
BLOOD & TISSUE PROTOZOA | PLASMODIUM
plasmodia that can form dormant in liver
(hypnozoite)
vivax
ovale
BLOOD & TISSUE PROTOZOA | PLASMODIUM
most dangerous/most pathogenic
falciparum
BLOOD & TISSUE PROTOZOA | PLASMODIUM
vector and definitive host
female anopheles mosquito
BLOOD & TISSUE PROTOZOA | PLASMODIUM
asexual reproduction is called
schizogony
BLOOD & TISSUE PROTOZOA | PLASMODIUM
cycle that happens outside the RBC (in the liver)
exo erythrocytic cycle
BLOOD & TISSUE PROTOZOA | PLASMODIUM
rupture releases ____
merozoites
BLOOD & TISSUE PROTOZOA | PLASMODIUM
cycle that happens inside RBC
erythrocytic cycle
BLOOD & TISSUE PROTOZOA | PLASMODIUM
once bitten by mosquito, it will acquire
gametocytes
BLOOD & TISSUE PROTOZOA | PLASMODIUM
cycle in mosquito
sporogonic cycle
BLOOD & TISSUE PROTOZOA | PLASMODIUM
presents with abrupt onset of fever and chills, accompanied by headache, myalgias, and arthralgias
malaria
BLOOD & TISSUE PROTOZOA | PLASMODIUM
Untreated malaria caused by P. falciparum is potentially life-threatening as a result of ____ and ____ damage.
extensive brain (cerebral malaria)
kdiney (blackwater fever)
BLOOD & TISSUE PROTOZOA | PLASMODIUM
drug that is first used in malaria
quinine
BLOOD & TISSUE PROTOZOA | PLASMODIUM
DOC
chloroquine
BLOOD & TISSUE PROTOZOA | PLASMODIUM
DOC for erythrocytic stage
chloroquine / quinine
BLOOD & TISSUE PROTOZOA | PLASMODIUM
DOC for exoerythrocytic stage
primaquine
BLOOD & TISSUE PROTOZOA | PLASMODIUM
DOC for gametogamy stage
quinine / primaquine
BLOOD & TISSUE PROTOZOA | PLASMODIUM
prophylaxis
cholorquine / doxycycline
BLOOD & TISSUE PROTOZOA | PLASMODIUM
patients resistant to malaria
- sickle cell anemia
- G6PD deficiency
- black people
BLOOD & TISSUE PROTOZOA | PLASMODIUM
radical cure of malaria
targets both active & dormant form
primaquine
BLOOD & TISSUE PROTOZOA
- Transmission: ingestion of cysts, transplacental transmission
- Congenital infection - during pregnancy.
o Can result in abortion, stillbirth, or neonatal disease with encephalitis, chorioretinitis, and hepatosplenomegaly. Fever, jaundice, and intracranial calcifications are also seen
TOXOPLASMA
BLOOD & TISSUE PROTOZOA | TOXOPLASMA
transmission
ingestion of cysts
transplacental (vertical)
BLOOD & TISSUE PROTOZOA | TOXOPLASMA
leading cause of blindness in children
congenital infection
BLOOD & TISSUE PROTOZOA | TOXOPLASMA
DOC
sulfadiazine
pyrimethamine