Morphine Sulfate

Question 1

Class / Action

Answer 1

Narcotic Analgesic

1. Potent Analgesic, Sedative, and Euphoric
2. Decreases Rate of AV Conduction (Vagotonic)
3. Peripheral Vasodilation and Venous Pooling of Blood

Question 2

Onset / Duration of Action

Answer 2

IV/IO: 5min IM: 10-30min / Duration IV/IO/IM: 4-5hrs

Question 3

Indications

Answer 3

Severe Pain (i.e. Myocardial Infarction, Burns, Isolated Extremity Injuries, Abdominal Pain)

Question 4

Contraindications

Answer 4

1. Known Hypersensitivity
2. Head Trauma
3. Altered States of Consciousness
4. Shock

Question 5

Precautions

Answer 5

1. Respiratory Depression (i.e. Associated with Asthma, COPD)
2. Elderly Patients
3. Hypotension
4. Pregnancy
5. Right-Ventricular Infarction

Question 6

Dosages / Administration

Answer 6

1. ADULT:
   a. Non-ACS Pain Management: 0.1mg/kg q 5-10min IM or SLOW IV/IO Push, Titrate to effect; Max Dose 20mg
   b. ACS Pain Management:
   i. STEMI: 2-4mg IV. May give additional doses of 2-8mg IV q 5-15min; Max Dose 10mg if Systolic BP>100
   ii. N-STEMI/ACS: 1-5mg IV only if symptoms not relieved by Nitrates or if symptoms recur; Max Dose 10mg if Systolic BP>100
2. PEDS: 0.1mg/kg IM or SLOW IV/IO Push; MAX Dose 10mg. CONTACT Mary Bridge Base Station for Additional Doses

Question 7

Adverse Reactions

Answer 7

Respiratory Depression, Respiratory Arrest, Hypotension, Nausea, Vomiting, Bradycardia, Heart Block, Drowsiness