Methylprednisolone (Solu-Medrol)

Question 1

Class / Action

Answer 1

Anti-Inflammatory/Corticosteroid / An Adrenocortical Steroid with potent anti-inflammatory effects

Question 2

Onset / Duration of Action

Answer 2

1-4hrs Onset / 7days Duration

Question 3

Indications

Answer 3

1. Moderate to Severe Asthma / COPD Exacerbations
2. Moderate to Severe Allergic Reactions
3. Moderate to Severe Angioedema
4. Anaphylaxis

Question 4

Contraindications

Answer 4

Known Hypersensitivity

Question 5

Precautions

Answer 5

Seizures may occur if pt is taking cyclosporin

Question 6

Dosages / Administration

Answer 6

1. ADULT: 125mg IV/IO, Single Dose Only
2. PEDS: 2mg/kg IV/IO; Max Dose 125mg
3. INCOMPATIBLE With Diphenhydramine; Flush Between Medications

Question 7

Adverse Reactions

Answer 7

1. None in the Acute setting

2. Some adverse metabolic effects if taken long-term, greater than a few weeks