Dopamine Flashcards
1
Q
Class / Action
A
Alpha/Beta Adrenergic Stimulator. Sympathomimetic. Dopaminergic.
- Increases BP
- At low dose of 1-5mcg/kg/min, Dopaminergic effects occur resulting in vasodilation of renal, mesenteric, and cerebral arteries increasing renal blood flow and urine output, but may not increase pulse or BP
- At dose of 2-20mcg/kg/min, beta adrenergic effects (increased contractibility and chronotropic effect) occur resulting in increased cardiac output with minimal changes in systemic vascular resistance or preload
- At does of 10-20mcg/kg/min, alpha-adrenergic effects occur resulting in vasoconstriction in the renal, mesenteric and peripheral arteries and veins.
2
Q
Onset / Duration of Action
A
Onset in 5min / Duration of 10min after infusion ends
3
Q
Indications
A
- Symptomatic hypotension s/t non-hypovolemic states
- Low cardiac output states such as cardiogenic, anaphylaxis, septic or neurogenic shock
- Symptomatic bradycardia after atropine/pacing
4
Q
Contraindications
A
- Uncorrected tachyarrhythmia d/t hypovolemia
- V-Fib
- Hypovolemic Shock
5
Q
Precautions
A
- Avoid extravasation of dopamine into surrounding tissue. If IV infusion infiltrates, it Must be Immediately Removed. Notify the physician.
- Do Not Mix with Sodium Bicarbonate or Similar Alkaline Solutions, because inactivation of Dopamine Will Result
6
Q
Dosages / Administration
A
- Dopamine Must be Diluted Prior to Administration; mix 400mg in 250mL NS with a micro-drip (1600mcg/mL)
a. Usual Infusion rate ranges from 2-20mcg/kg/min, titrations to individual patient response - May Use: DUGGAN FORMULA
a. Estimate Pt’s weight in pounds
b. Cross off the 3rd digit of the weight in pounds to get gets/min, (e.g. 183lbs = 18gtts/min)
c. At 18gtts/min, you would be administering 5-6mcg/kg/min - May Use: Patient Weight in kg
a. See Chart in Protocol Book
7
Q
Adverse Reactions
A
Hypersensitivity, SVT, Ventricular Arrhythmias (PVCs, V-Tach, V-Fib)
