Calcium Gluconate (10%)

Question 1

Class / Action

Answer 1

Electrolyte - Calcium Salt

1. Involved in regulation of cell membrane permeability to sodium and potassium
2. Plays a role in excitation contraction coupling (increases force of myocardial and muscle contraction)

Question 2

Onset / Duration

Answer 2

Immediate Onset / 30min - 2hours Duration of Action

Question 3

Indications

Answer 3

1. Suspected Hyperkalemia exhibiting tall, peaked T-waves, QRS Prolongation, low P-waves
2. Calcium-channel blocker or beta-blocker overdose
3. Antidote for magnesium sulfate toxicity
4. Crush Injury Syndrome Hyperkalemia

Question 4

Contraindications

Answer 4

1. Ventricular fibrillation
2. Digitalis intoxication (may result in Asystole)
3. Hypercalcemia

Question 5

Precautions

Answer 5

1. Extravasation causes tissue sloughing
2. Dehydration
3. Do Not Mix with Sodium Bicarbonate (flush line first)

Question 6

Dosages / Administration

Answer 6

1. 10% = 100mg/mL
2. ADULT: 3g/5min IV/IO; May repeat in 20min PRN
3. PED: 60mg/kg SLOW IV/IO Push

Question 7

Adverse Reactions

Answer 7

1. Bradycardia, Asystole, Ventricular Fibrillation

2. Mild to Severe IV site irritation