Dextrose (5%/D5W 10%/D10W 25%/D25W 50%/D50W)

Question 1

Class / Action

Answer 1

Simple Carbohydrate

1. Provides glucose required for metabolic needs
2. Spares body proteins

Question 2

Onset / Duration of Action

Answer 2

Immediate Onset / Duration of Action Varies

Question 3

Indications

Answer 3

1. Suspected hypoglycemia
2. Coma of unknown origin
3. Crush Injury Syndrome
4. Routine IV administration

Question 4

Contraindications

Answer 4

Hyperglycemia

Question 5

Precautions

Answer 5

Increased ICP in constant infusion

Question 6

Dosages / Administration

Answer 6

1. Hypoglycemia:
   a. ADULT: Titrate and/or repeat until pt at baseline and BGL remains >80
   i. 50mL of D50W (25gm) IV/IO Push, or
   ii. 250mL of D10W (25gm) IV/IO Push
   b. PED: Titrate and/or repeat until pt at baseline and BGL remains >60
   i. 50% dextrose (0.5gm/mL) (>7years old); give 1mL/kg, or
   ii. 25% dextrose (0.25gm/mL); give 2mL/kg, or
   iii. 10% dextrose (0.1mg/mL); give 5mL/kg, or
   iv. 5% dextrose (0.05gm/mL); give 10mL/kg if volume tolerated.
   v. Maximum concentration for NEWBORN: 12.5% (0.125gm/mL)
2. IV Maintenance: D5W ADULT and PED: Route and indication dependent.

Question 7

Adverse Reactions

Answer 7

Extravasation cause tissue sloughing with D25W and D50W