Dexamethasone (Decadron)

Question 1

Class / Action

Answer 1

Glucocorticoid

1. Synthetic steroid that is related chemically to the natural hormones secreted by the adrenal cortex
2. Suppresses acute and chronic inflammation
3. Potentials the relaxation of vascular and bronchial smooth muscle by beta adrenergic agonists
4. Possibly alters airway hyperactivity

Question 2

Onset / Duration of Action

Answer 2

IV: 1hour PO: 2hours / 24-72hours Duration

Question 3

Indications

Answer 3

1. Moderate to severe asthma, croup or COPD
2. Moderate to severe allergic reactions
3. Moderate to severe angioedema
4. Anaphylaxis

Question 4

Contraindications

Answer 4

Known Hypersensitivity

Question 5

Precautions

Answer 5

1. Active untreated infections
2. Incompatible with Diphenhydramine; Flush between meds
3. Medication should be protected from heat

Question 6

Dosages / Administration

Answer 6

1. ADULT: 0.6mg/kg IV/PO up to 10mg
2. PED: 0.6mg/kg IV/PO up to 10mg
3. Incompatible with Diphenhydramine; Flush between meds
4. Medication should be protected from heat

Question 7

Adverse Reactions

Answer 7

Hypertension, GI Bleeding, Hyperglycemia