Lecture 7: Capillaries and Lymphatics Flashcards
What is the function of Capillaries?
Site of exchange between blood and tissues
What does the large total area of the capillary bed compared to arterioles mean?
Much slower blood flow
What are 3 features of capillaries?
- Very thin walls
- Large total cross sectional area of capillary bed
- Slow & smooth blood flow
What are erythrocytes?
Red blood cells
Why are Capillaries only approximately 1 red blood cell in width?
Reduces the distance from the red blood cell to the surrounding tissue
What type of intercellular junction fuses the Capillary cell shut?
Tight junctions
What drains into Capillary beds?
Arterioles
What drains from the Capillary beds?
Venules
What is the role of the Precapillary sphincters?
Constrict to stop blood going into the Capillary beds
What is the name of the pathway that allows blood from the arteriole to the venules without passing through the exchange surface?
The Vascular shunt
Why is blood shunted away from the capillary beds?
To stop heat loss from blood and keep it away from the skin surface
What are Precapillary sphincters composed of?
Smooth muscle cells
What are the 3 types of Capillaries?
- Continuous
- Fenestrated
- Sinusoidal
What components make up a Capillary?
3
- Basement membrane
- Endothelial layer
- Intercellular cleft
What produces the Basement membrane?
The endothelial cell of the Capillary
What do substances have to pass through from the Capillaries to go to the tissue?
Both the Endothelial cell and the basement membrane
What is an intercellular cleft?
A channel between two cells through which molecules may travel
What do vesicles in the Capillaries do?
They carry things that can’t move by passive diffusion
Where are continuous Capillaries likely to be found?
Skeletal and Cardiac muscle
What are the openings in fenestrated capillaries?
Small porous openings/physical openings