Lecture 7 & 8 - Simple Circuits, Vision Flashcards

0
Q

Describe convergent pathways of neurons, and give an example in the body

A

This is when many neurons fire onto on target cell

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1
Q

Describe divergent pathways of neurons and give an example in the body

A

This is one when neuron splits at the axons to interact with many target cells.

This happens with lower motor neurons, which split to active many muscle fibres making up a motor unit

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2
Q

Which part of the neuron receives input?

A

The dendrites

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3
Q

Distinguish IPSPs and EPSPs

A

EPSPs: when excitatory cells input to a neuron, they bring about the depolarisation of a small segment of the dendrite on the cell body. These will add together to trigger an action potential

IPSPs: when inhibitory cells input onto a neuron, they bring about a hyper polarisation of a region of the cell body. This makes it more unlikely that an action potential will fire

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4
Q

The axon hillock determines whether or not an action potential will fire based on the balance between …

A

IPSPs and EPSPs

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5
Q

What sort of input will have a greater impact on the likelyhood of an AP firing?

A

One near the axon hillock

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6
Q

What happens once an action potential reaches the axon terminal?

A

There is no more depolarisation at the terminal because there are no more sodium channels in the membrane

  1. Voltage gated calcium channels open, and calcium rushes into the cell
  2. Synaptic vesicles fuse with the membrane, releasing neurotransmitters into the synaptic cleft
  3. These neuro transmitters interact with receptors on the post-synaptic membrane
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7
Q

Why is time important when considering graded potentials?

A

If they occur in quick succession they will summate and cause an action potential to fire

If they are more spread out, they won’t summate and won’t get the axon hillock to threshold

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8
Q

How will a strong neurotransmitter stimulus alter the firing of action potentials compared to a weak stimulus?

A

It will not alter the magnitude of the action potential, only the firing rate

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9
Q

What is pre synaptic inhibition?

A

An inhibitory neuron inhibits one of the axon terminals just before it synapses

This selectively inhibits one of the targets

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10
Q

What is post-synaptic inhibition?

A

This is when an inhibitory cell inputs onto the cell body, inhibiting the entire cell.
All targets of this cell are now inhibited

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11
Q

… are variant and … are invariant

A
  1. Graded potentials

2. Action potentials

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12
Q

Differentiate between conscious sensing and unconscious sensing

Give some examples of each

A

Conscious: we know that we are perceiving these things
Vision, pain, heat, taste, smell

Unconscious: we don’t perceive them
Blood pressure, heart rate, osmolarity

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13
Q

Differentiate between senses that use neurons to sense the environment and senses that use specialised cells

A

Neurons: smell, ORC

Specialised cells: vision, hearing, mechanoreptioon

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14
Q

What are the four classes of receptor?

A

Thermoreceptor
Mechanoreceptor
Chemoreceptors
Photoreceptor

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15
Q

In vision, what is being sensed?

A

Photons

16
Q

In hearing what is being sensed?

A

Vibration

17
Q

In touch, what is being sensed?

A

Vibrations

18
Q

In taste, what is being sensed?

A

Molecules

19
Q

Describe the generalised pathway of information from the sensor to the brain

A

Sensor delivers information to spinal cord, which projects up to the thalamus, which sorts information and sends it to a specific region of the brain responsible for that sense

20
Q

Describe the path that information about vision takes

A

Rod / cone cell
Bipolar cell
Ganglion cell

21
Q

What are the differences between rods and cones

A

Rods

  • black and white
  • one type
  • many of the them

Cones

  • colour vision
  • three types
  • few in number, segregated in the fovea
22
Q

Describe the process of photo transduction

A
  1. Photon passes through eye to the photoreceptor cell
  2. 11-cis retinal –> trans-retinal in rhodopsin
    Transducin activated
  3. cGMP phosphodiesterase activated
  4. cGMP degraded
  5. Ion channels shut
  6. Cell hyperpolarised
  7. Neurotransmitters no longer released
24
Q

What is the effect on bipolar cells that tells them that there is light present?

A

No more neurotransmitters received

25
Q

How can the amount of neurotransmitter released by a neuron vary?

A

Strength of stimulus
• stronger stimulus will lead to the firing of more action potential
• more neurotransmitter released

26
Q

Compare ‘Type of Signal’ for graded and action potentials

A

Graded: input signal

Action: conduction signal

27
Q

Compare the location of graded and action potentials

A

Graded: cell body & dendrites

Action: trigger zone & axon

28
Q

Compare ‘strength of signal’ in graded and action potentials

A

Graded: variable

Action: constant

29
Q

What is Henneman’s rule of motor unit recruitment?

A

Smaller motor units are recruited before large motor units

30
Q

Why are small motor neurons more excitable?

A

?

31
Q

Will an axon with a greater or lesser diameter conduct an action potential more quickly?
Why?

A

Larger diameter → faster conduction
• less membrane leak
• less resistance