Lecture 3 Flashcards

1
Q

the amount of blood ejected from the heart in 1 minute is known as the ___ ___

A

cardiac output

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2
Q

amount of blood received by ventricle must be ___ to the amount of blood pumped out of the ventricle

A

equal to

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3
Q

amount of blood pumped out by the left ventricle must be ___ to the amount of blood pumped out by the right ventricle

A

equal to

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4
Q

how to calculate cardiac output?

A

stroke volume X heart rate

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5
Q

if the volume of blood pumped by the left side of the heart was less than that pumped by right side of the heart, what would be the result?

A

pulmonary edema

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6
Q

if the volume of blood pumped by the right side of the heart was less than that pumped by left side of the heart, what would be the result?

A

systemic edema

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7
Q

what’s the difference b/n the max and resting cardiac output?

A

cardiac reserve

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8
Q

what is stroke volume?

A

volume of blood ejected by a ventricle in one contraction of the heart

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9
Q

what is the volume of blood ejected by each ventricle in one minute?

A

cardiac output

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10
Q

what is tachycardia?

A

resting adult HR > 100 bpm

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11
Q

the amount of blood ejected by a ventricle is ___ the amount of blood received during ventricular filling

A

the same as

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12
Q

what is bradycardia?

A

resting adult HR < 60 bpm

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13
Q

what is the steady background firing of the vagus nerve to the heart?

A

vagal tone

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14
Q

what is too much calcium in blood?
how does that affect HR?

A

hypercalcemia –> lowers HR

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15
Q

what is calcium deficiency in blood?
how does that affect HR?

A

hypocalcemia –> raises HR

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16
Q

what chemicals cause increase in HR?

A

nicotine
thyroid hormone
caffeine

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17
Q

what is vagal tone?

A

steady background firing of the vagus nerve to the heart

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18
Q

the amount of tension in the ventricular myocardium immediately before it begins to contract is known as the ___

A

preload

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19
Q

A decrease in venous return to the heart leads to a(n) ______ in preload, and therefore, a(n) ______ in stroke volume.

A

decrease, decrease

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20
Q

what does the Frank-Starling law of the heart state?

A

stroke volume is proportional to end-diastolic volume

21
Q

what is the strength of contraction for a given preload called?

A

contractility

22
Q

glucagon and thyroid hormone ___ HR

A

increase

23
Q

the amount of tension in the ventricular myocardium immediately before it begins to contract is called what?

A

preload

24
Q

what do positive inotropic agents do?

A

increase contractility

25
Q

what do positive inotropic agents do?

A

increased contractility

26
Q

an increase in venous return to the heart leads to an ___ in preload and therefore an ___ in stroke volume

A

increase, increase

27
Q

what is the most common cause of coronary artery disease?

A

artherosclerosis

28
Q

which law states that stroke volume is determined by the end-diastolic volume?

A

Frank-Sterling

29
Q

what is afterload?

A

the sum of all forces a ventricle must overcome before it can reject blood

30
Q

how does hypertension affect afterload?

A

increases it

31
Q

the strength of a contraction for a given preload is defined as the ___ of the myocardium

A

contractility

32
Q

the flow of blood per given volume or mass of tissue is known as ___

A

perfusion

33
Q

nicotine increases heart rate by increasing the secretion of what?

A

catecholamine

34
Q

what is blood pressure?

A

force that blood exerts against a vessel wall

35
Q

what is the effect of negative ionotropic agents?

A

decrease contractility

36
Q

what is the narrowing of coronary arteries, usually by atherosclerosis?

A

coronary artery disease

37
Q

what is systolic pressure minus diastolic pressure?

A

pulse pressure

38
Q

Which force impedes the opening of the semilunar valves and opposes ventricular ejection?

A

afterload

39
Q

Systolic pressure is the highest in which vessel?

A

aorta

40
Q

increasing stiffness of arteries =

A

arteriosclerosis

41
Q

what is normal BP?
what is BP for hypertension?
what is BP for hypotension

A

120/80
> 140/90
varies

42
Q

BP is determined by what 3 variables?

A

resistance to flow
blood volume
cardiac output

43
Q

the difference b/n systolic and diastolic pressure is ___ pressure

A

pulse

44
Q

what affects peripheral resistance?

A

blood viscosity
vessel length
vessel radius

45
Q

Degenerative changes of the blood vessels characterized by the presence of atheromas and often leading to calcification of the vessel wall is known as ___

A

atherosclerosis

46
Q

what is atherosclerosis?

A

degenerative changes of the blood vessels characterized by the pressure of atheroma and often leading to calcification the vessel wall

47
Q

what is true in a reclining individual?

A

mean arterial pressure is higher in the arm compared to the foot

48
Q

how does radius of blood vessel affect blood flow?

A

F (is proportional to) r^4

3-fold increase in radius ==> 81-fold increase in flow

49
Q

which arteries exert the greatest control over peripheral resistance and blood flow?

A

arterioles