Lecture 25 -- review questions Flashcards
during the first weeks of pregnancy, what organ is the primary source of pregnancy-related hormones?
and after that few weeks, what organ takes control of the hormone production?
corpus luteum –> first weeks
placenta –> later weeks
what does hCG stand for?
human chorionic gonadotropin
what is the function of the human chorionic gonadotropin?
prevents involution of corpus luteum
stimulates its growth and secretory activity
when do hCG levels peak: early, mid, or in late (~week 40) pregnancy?
early (~week 10)
what is one of the functions of the placental lactogen?
makes glucose more available to the fetus
fatty acids more available to the mom
when do placental lactogen levels peak: early, mid, or in late (~week 40) pregnancy?
around late pregnancy
~week 30
right before birth
what are the 3 functions of progesterone in pregnancy?
1) inhibit premature uterine contractions and menstruation
2) stimulate endometrial stromal cell differentiation into decidual cells that control embryo implantation
3) stimulate mammary alveoli development
what hormone prevents premature uterine contractions and menstruation (=destruction of the functional layer of the endometrium) during pregnancy?
progesterone
what does progesterone do to the endometrium?
stimulate endometrial stromal cells to differentiate into decidual cells –> control embryo implantation
when do progesterone levels peak: early, mid, or in late (~week 40) pregnancy?
late pregnancy
around birth
when do estradiol (estrogen) levels peak: early, mid, or in late (~week 40) pregnancy?
late pregnancy
around birth
when do cortisol levels peak: early, mid, or in late (~week 40) pregnancy?
late pregnancy
around birth
what is one of the functions of cortisol in pregnancy?
to mobilize amino acids for fetal protein synthesis
are progesterone and estradiol being synthesized during the first weeks of pregnancy or only at the end?
during first weeks and at the end
start –> synthesized by corpus luteum
end –> synthesized by placenta
what does relaxin do?
(from ovaries and placenta)
relaxes the pelvis and widens the cervix
what organs synthesize relaxin?
ovaries and placenta
during pregnancy, what happens to the tidal volume? why? (tip: 2 reasons)
increase:
1) greater need for oxygen
2) progesterone increases the sensitivity of the medullary respiratory center to CO2
what results from the influence of progesterone on the maternal respiratory system?
increases the sensitivity of the medullary respiratory center to CO2
what does dyspnea mean?
(difficult breathing)
why is dyspnea typical of the 3rd trimester of pregnancy?
diaphragm is pushed superiorly by the increasing size of the uterus
why do pregnant women suffer from heartburn?
and hemorrhoids, varicose veins, or edema?
enlarging uterus presses upward on stomach –> causes gastric reflux
uterus puts pressure on the large pelvic blood vessels –> interferes w/ venous return from the legs and pelvic regions
what are varicose veins?
twisted, enlarged, damaged veins
blood doesn’t flow well back to the heart
what happens with the total body water of the pregnant: increase or decrease?
how about blood volume and cardiac output?
and urine volume?
total body water –> increase
blood volume –> increase
cardiac output –> increase
urine volume –> increase
why are frequent urination and urgency common in pregnancy?
kidneys produce more urine
enlarged uterus puts pressure on bladder
what causes constipation in pregnancy?
decreased intestinal mobility
more nutrients absorbed
what are 2 typical changes that happen in the skin during pregnancy?
changes in pigmentation:
- more melanocyte activity –> darker skin in some areas
stretch marks
what is the linea nigra? which cells are implicated in the emergence of the linea nigra?
linea nigra == dark line from umbilical to pubic region –> line on belly
increased melanocyte activity
what is labor?
a series of continuous, progressive contractions of the uterus
–> help the cervix to dilate and to thin
–> allow the fetus to move thru the birth canal
what is parturition?
process of giving birth
what are Braxton Hicks contractions?
“false labor”
weak, irregular contractions