Kawasaki Disease

Question 1

What is Kawasaki Disease?

Answer 1

A disease of unknown cause that results in inflammation of small to medium vessels

Question 2

What is the epidemiology of Kawasaki Disease?

Answer 2

Kawasaki disease is mostly seen in children under 5 years

Question 3

What are the differential diagnoses of Kawasaki disease?

Answer 3

Streptococcal infection
Staphylococcal infection
Scarlet fever
Rheumatic fever
Toxic shock syndrome

Question 4

What criteria is used to diagnose Kawasaki disease?

Answer 4

Fever for more than 5 days plus 4 out of the 5 following criteria:
- Changes to extremities
- Rash
- Cervial lymphadenopathy
- Non-exudative conjunctivitis
- Lip and mouth changes

Question 5

What is the first line management of Kawasaki disease?

Answer 5

IVIg within 10 days of presentation
High dose aspirin

Question 6

What other medications may be considered in Kawasaki disease?

Answer 6

Coricosteroids
Infliximab

Question 7

What investigations are used to diagnose Kawasaki disease?

Answer 7

FBC
ESR
CRP
Echo

Question 8

What are the complications of Kawasaki disease?

Answer 8

Pericarditis
Myocarditis
Coronary aneurysm