IgA vasculitis Flashcards
What are the features of IgA vasculitis?
Purpuric non-blanching rash
Joint pain
Abdominal pain
Kidney problems
What is the epidemiology of IgA vasculitis?
Male sex
Age 2-10
Previous upper respiratory tract infection
What are the differentials of IgA vasculitis?
Meningococcal septicaemia
Thrombotic thrombocytopenic purpura
Kawasaki disease
Granulomatosis with polyangiitis
SLE
Rheumatoid arthritis
How is IgA vasculitis investigated?
Urinalysis
Skin or renal biopsy
Blood pressure
Blood creatinine
Abdominal or renal ultrasound
What is the aetiology of IgA vasculitis?
IgA is deposited in the small vessels, which become inflamed and leak blood
What is the treatment of IgA vasculitis?
Disease is usually self limiting
Corticosteroids can be given to prevent kidney damage
What supportive treatments can be given in IgA vasculitis?
NSAIDs for joint pain
Corticosteroids for kidney damage
What other medications can be considered for kidney protection?
ACE inhibitor
Immunosuppressants
What is the main complication of IgA vasculitis?
Reduced renal function
