Histology of accessory organs Flashcards
The liver is a solid organ composed of tightly packed pink staining plates called
Hepatocytes.
collagenous capsule into the outer surface of liver -coverd by ?
mesothelial layer from the peritoneum
spaces that lie between hepatocytes
and are vascular seen, as pale-stained spaces between plates of liver cells.
Sinusoids
sinusoids form low resistance system of ……….
very channels allowing blood to be in contact with hepatocytes.
which tissue is found most in the portal tract, which contains what ?
collagenous tissue and contains main blood vessels running into liver.
a structure running in the portal tracts is
bile ducts.
Terminal hepatic venules .
are also called centrilobar venules which drain the liver and are tributaries of hepatic veins which shunt blood to the inferior vena cava.
hepatocytes
are large polyhedral cells with round nuclei, peripherally dispersed chromatin and prominent nucleoli. binucleate cells are common.
Cytoplasm has variable appearance
Brown granules of wear-and-tear pigment lipofuscin
what cells line the sinusoid ?
lined by flat endothelial cells which are distinguished by the flattened condensed nuclei.
small-diameter thick walled vessesls
are terminal branches of hepatic arteries.
Bile canaliculi
drains into bile-collecting ducts
is lined by simple cuboidal or columnar epithelium, and drains into bile ductules.
ductules emerge forming what structure and that structure drains into what?
larger trabecular ducts that drain via intrahepatic ducts into right and left hepatic ducts.
hepatocytes are collectively termed?
limiting plate, surrounding thebportal tract
hepatocytes are collectively termed?
limiting plate, surrounding the portal tract
hepatocytes are collectively termed?
limiting plate, surrounding the portal tract
Reticulin of the liver
maintains the structural integrity of the liver, in form of a meshwork of reticulin fibers (collagen type 3)
functions of reticulin
Supports hepatocytes and sinusoidal lining cells.
Merges with collagenous supporting tissue of portal tract and terminal hepatic venule.
At periphery of liver, reticulin is continuous with capsule that invests external surface of liver
sinusoids lining
they are lined by fanestrated
sinusoids lining
they are lined by fenestrated endothelium with no basement membrane, is separated from hepatocytes by narrow space which drains into lymphatics of portal tracts.
Hepatic vasculature.
Hepatic portal vein and hepatic artery branch repeatedly within liver
Terminal branches run within portal tracts and empty into sinusoids
Blood from both systems filters between plates of hepatocytes in sinusoids which then drain into terminal hepatic venule
Bile secreted into bile canaliculi between plasma membranes of adjacent hepatocytes
Then drains into system of bile ducts in portal tracts
name the structural unit of the liver ?
liver lobule.
Roughly hexagonal in shape, centred on a terminal hepatic venule
Portal tracts are positioned at angles of the hexagon
Blood from portal vein and hepatic arteries flows away from portal tract to adjacent central veins
a physiologically useful model of liver anatomy?
hepatic acinus.
a berry-shaped unit of liver parenchyma centred on the portal tract and lies between two or more terminal hepatic venules.
acinus.
blood flows from portal tracts through sinusoids to venules
irregular hexagonal boundary at lobule is defined by
portal tract and space collagenous tissue.