Heparin

Question 1

Heparin Trade Name?

Answer 1

Heparin

Question 2

Heparin Classification?

Answer 2

Anticoagulant

Question 3

Heparin Mechanism?

Answer 3

Binds to antithrombin which blocks the conversion of prothrombin to thrombin and prevents the conversion of fibrinogen to fibrin thereby inhibiting factors 3 and 10.

Question 4

Heparin Indications?

Answer 4

Treatment of thromboembolic disorders (DVT, PE)

Question 5

Heparin Contraindications?

Answer 5

-Hypersensitivity
-Active Bleeding
-Recent intracranial, intraspinal, or eye surgery
-Severe hypertension

Question 6

Heparin Side Effects/Precautions?

Answer 6

-Hemorrhage
-Hematuria
-GI Bleeding
-Shock
-Pain
-Bruising
-Thrombocytopenia

Question 7

Heparin Adult Dose?

Answer 7

Bolus: 60 U/kg, max 4,000 U IV/SQ
Infusion: 12-15 U/kg/hr, max 1,000 U/hr

Question 8

Heparin Pediatric Dose?

Answer 8

Not recommended

Question 9

Heparin Onset of Action?

Answer 9

Immediate IV; 20-60 minutes SQ

Question 10

Heparin Duration of Action?

Answer 10

4-8 Hours

Question 11

Heparin Max Dose Adult/Pediatric?

Answer 11

1,000 - 4,000 Units depending on underlying condtion.

Question 12

Heparin Routes of Administration?

Answer 12

IV, SQ

Question 13

Heparin How Supplied?

Answer 13

25,000U/250ml premixed solutions (50 U/ml)