Lorazepam

Question 1

Lorazepam Trade Name?

Answer 1

Ativan

Question 2

Lorazepam Classfication?

Answer 2

Benzodiazepine

Question 3

Lorazepam Mechanism?

Answer 3

Binds to specific sites on GABA Type A receptors and via an allosteric affect it hyperpolarizes to potentiate the effects for GABA resulting in sedation and suppression of convulsions.

Question 4

Lorazepam Indications?

Answer 4

-Restraint
-TBI
-Hyperthemia
-Sympathomimetic/Anticholinergic OD
-TCP/DC Cardioversion
-Organophosphate
-Anxiety
-Alcohol Withdrawl
-Seizure

Question 5

Lorazepam Contraindications?

Answer 5

-Hypersensitivity
-Respiratory Insufficiency
-Hypotension

Question 6

Lorazepam Side Effects/Precautions?

Answer 6

-Dizziness
-Drowsiness
-Confusion
-Hypotension
-Nausea/Vomiting
-Respiratory depression

Question 7

Lorazepam Adult Dose?

Answer 7

1mg - 4mg

1mg (0.1mg/kg)- TBI, Hyperthermia, Sympathomimetic/Anticholinergenic, TCP/DC, Organophosphate, Anxiety, Alcohol W/D,
2mg (0.1mg/kg) - Restraint
4mg - (0.1mg/kg) Seizure

Question 8

Lorazepam Pediatric Dose?

Answer 8

1/10th of the adult dose

Question 9

Lorazepam Onset of Action?

Answer 9

1-5 minutes

Question 10

Lorazepam Duration of Action?

Answer 10

Potentailly Hours

Question 11

Lorazepam Max Dose Adult/Pediatric?

Answer 11

8mg and 2mg respectively but highly dependeng on indication

Question 12

Lorazepam Routes of Administration?

Answer 12

IV/IO/IM/IN depending on indication

Question 13

Lorazepam How Supplied?

Answer 13

2mg/ml and 4mg/ml vials and ampules