Tranexamic Acid

Question 1

Tranexamic Acid Trade Name?

Answer 1

Lysteda, Cyklokapron

Question 2

Tranexamic Acid Classfication?

Answer 2

Antifibrinolytics

Question 3

Tranexamic Acid Mechanism?

Answer 3

Inhibitis TPA which stops plasminogin from binding to fibrin thereby inhibiting fibrinolysis.

Question 4

Tranexamic Acid Indications?

Answer 4

Hemorrhagic shock

Question 5

Tranexamic Acid Contraindications?

Answer 5

-Injury time > 3 hours
-Pregnancy
Known history of thromboembolic disease (DVT, PE, etc.)
-Use of anticoagulants (warfarin, lovenox, etc.)
-Hemophilia

Question 6

Tranexamic Acid Side Effects/Precautions?

Answer 6

-Abdominal or stomach pain, discomfort, or tenderness.
-chills or fever.
-difficulty with moving.
-headache, severe and throbbing.
-joint or back pain.
-muscle aching or cramping.
-muscle pains or stiffness.

Question 7

Tranexamic Acid Adult Dose?

Answer 7

Loading: 1 g in 100 ml NS over 10 minutes
Maintenance: 1 g over 8 hours

Question 8

Tranexamic Acid Pediatric Dose?

Answer 8

Not recommended. Safety not established.

Question 9

Tranexamic Acid Onset of Action?

Answer 9

5-10 minutes

Question 10

Tranexamic Acid Duration of Action?

Answer 10

2-5 hours

Question 11

Tranexamic Acid Max Dose Adult/Pediatric?

Answer 11

2g

Question 12

Tranexamic Acid Routes of Administration?

Answer 12

IV Drip

Question 13

Tranexamic Acid How Supplied?

Answer 13

1g vials