Mannitol Flashcards
Mannitol Trade Name?
Osmitrol
Mannitol Classification?
Osmotic Diuretic
Mannitol Mechanism?
Increases plasma tonicity which promotes movement of water out of the brain parenchyma and into the intravascular space.
Mannitol Indications?
Cerebral Edema/ICP
Mannitol Contraindications?
-Hypotension
-Pulmonary edema
-Severe dehydration
-Intracranial bleeding
Mannitol Side Effects/Precautions?
- Headache
- Seizures
- Confusion
- Tachycardia
- Chest pain
- Hypertension
- Hypotension
- Nausea/vomiting
- Pulmonary edema
- Dehydration
Mannitol Adult Dose?
0.25-2.0 g/kg over 5 - 10 minutes
Mannitol Pediatric Dose?
0.25-2.0 g/kg over 5 - 10 minutes
Mannitol Onset of Action?
5-10 minutes
Mannitol Duration of Action?
~6 hours
Mannitol Max Dose Adult/Pediatric?
no noted. *stat pearls
Mannitol Routes of Administration?
IV/IO
Mannitol How Supplied?
250ml and 500ml bags of 20% solution (200mg/ml)