FN: Meningitis Flashcards

1
Q

Features

A

Meningitic
Neurological
Septic

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2
Q

Meningitic

A

HEadache
Neck stiffness
Photophobia
n/v

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3
Q

Neck stiffness signs

A

Kernigs

Brudzinskis

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4
Q

Kernigs

A

Straightening leg with hip @ 90degrees

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5
Q

Brudzinski’s

A

Lifting head –> lifting of legs

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6
Q

Neurological

A

reduced GCS - coma
Seizures (20%)
Focal neuro (20%) e.g. CN palsies

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7
Q

Septic

A
Fever
low BP, high HR
Raised CRT
purpuric rash
DIC
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8
Q

Abx therapy

A
  1. Community: benpen 1.2g IV/IM
  2. 50 ceftriaxone + ampicillin 2g IVI/4h
  3. If viral syspected: aciclovir
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9
Q

Organisms

A
  1. viruses: enteroviruses (Coxsackie, echovirus), HSV2
  2. Meningococcus
  3. Pneumococcus
  4. Listeria
  5. Haemophilus
  6. TB
  7. Cryptococcus
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10
Q

Investigations

A

Bloods: FBC, U+E, clotting, glucose, ABG

Blood cultures

LP: MCS, glucose, virology/PCR, lactate

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11
Q

Acute Management

Step 1

A

ABC

  1. Oxygen 15L - SpO2 94-98%
  2. IVI fluid resus with crystalloid

distinguish between septicamic or Meningitis

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12
Q

Mainly septicaemic treat with

A
  1. Dont attempt LP
  2. Ceftriaxone 2g IVI
  3. Consdier ITU if shocker
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13
Q

Mainly Meningitis

A
  1. If no shock or CIs do LP
  2. Dexamethasone 0.15mg/kg IV QDS
  3. Ceftiaxone 2g IVI post-LP
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14
Q

Prophylaxis for nearby people

A

Rifampicin

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15
Q

Contraindications for an LP:

Try LP Unless ContraINdicated

A
Thrombocytopenia
LAteness (delay in antibiotic admin)
Pressure (Cardio + resp systems)
Unstable (Cardio + resp systems)
Coagulation disorder
Infection at LP site
Neurology (focal neurological signs)
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16
Q

Findings in CSF for Bacterial

A

Apperance: Turbid
Cells: PMN
Count: 100-1000
Glucose: low (1.5)

17
Q

CSF findings in TB meningitis

A

Apperance: fibrin web
Cells: Lympho/mononuc
Count: 10-1000
Glucose: low (

18
Q

CSF findings in Viral

A
AppearanceL Clear
Cells: Lympho/mononuc
Count: 50-1000
Glucose:>1/2 plasma
Protein mild