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Final Notes > FN: Diabetes Insipidus > Flashcards

FN: Diabetes Insipidus Flashcards

1
Q

Symptoms

A

Polyuria
Polydypsia
Dehydration
Hypernatraemia: lethargy, thirst, coma, confusion

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2
Q

Causes

A

Cranial

Nephrogenic

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3
Q

Cranial

A 
Idiopathic:50%
Congenital
Tumours
Trauma
Vascular: haemorrhage (Sheehans syn.)
Infection: meingoencephalitis
Infiltration: sarcoidosis
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4
Q

Nephrogenic causes

A

Congenital
Metabolic: reduced K, increased Calcium
Drugs: Lithium, vaptans, demecleocycline
Post-obstructive uropathy

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5
Q

Investigations

A

Bloods: U+E, Calcium, Glucose

Urine and plasma osmolality

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6
Q

Can exclude DI if

A

U:P osm >2

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7
Q

Diagnostic test

A

Water deprivation test with desmopressin trial

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8
Q

Differential

A

DM
Diuretics or Lithium
Prmary polydypsia

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9
Q

Treatment for cranial

A

find cause: MRI brain

Desmopressin PO

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10
Q

Nephrogenic treatment

A

Treat cause

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Final Notes (196 decks)

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