Emergencies Flashcards
Drugs and substances that may produce allergic reactions
- Local anaesthetics
- Antibiotics
- Analgesics
- Anxiolytic drugs
- Dental materials
Most common preservative in local anaesthetics that causes allergy
Paraben
Most common antibiotic producing allergic reaction
-Penicillin
Most common analgesics responsible for allergic reactions
- Codeine(narcotics)
- Aspirin (acetylsalicylic acid)-urticaria to anaphylactic shock
Anxiolytic drugs that commonly cause allergy
-Barbiturates (mild-urticaria)
Dental materials that commonly cause allergy
-Acrylic resins
-Antiseptics
-Radiograph processing solutions
-Gloves
(Mild-stomatitis and skin urticaria)
Classification of allergic reactions
- Type I- Anaphylaxis
- Type II- cytotoxic hypersensitivity
- Type III- Immune complex mediated hypersensitivity
- Type IV-Cell mediated or delayed type hypersensitivity
Types of allergic reactions
- Anapylaxis
- Urticaria
- Quinckes Edema
- Allergic Asthma
Precautionary measures for allergy
- Questions about type of allergy
- Referral for allergy testing
- Prepared to deal with allergic reaction with drugs(adrenaline, hydrocortisone, antihistamines and oxygen)
Anaphylaxis
- Acute respiratory and circulatory collapse
- Hoarseness of voice, anxiety, wheezing, irregular heart rate
- Fatal within 5-10 mins
Anaphylaxis treatment
- Termination of treatment-patient put in Trendelenburg position
- Adrenalin(0.3-0.5ml) giving i.v or i.m
- Control of vitals
- Hypotension treatment wit NaCl(i.v)
Anaphylactic shock treatment
- Adrenalin(0.5ml 0.1%) diluted in NaCl(o.9%) i.v
- Urbason (1-3mg/kg i.v)
- Salbutamol (5mg iv)
- Droperidol(for throes)
- CPR
Urticaria
- Most common reaction
- Vesicles due to histamine and serotonin→ increased permeability of vascular structures
- Vesicles induce pruritis and burning sensation on skin→ limited or spread over body
- Severe reaction→fall in blood volume→ anaphylaxis
Urticaria treatment
- Termination of treatment-patient in Trendelenburg position
- Adrenaline (0.3ml 0.1%) s.c, i.m or i.v
- Allergosan(1% 2ml) i.v or i.m
- Patient observed for 1 hour
- Oral antihistamines
Quinckle’s Edema
- Swelling of soft tissues(lips, tongue, buccal mucosa, epiglottis)
- Obstruction of upper respiratory tract→ dyspnoea and difficulty swallowing
Quincke’s edema treatment
- Adrenaline(0.3mk 0.1%) i.v or i.m
- Methylprednisolon i.v
- NaCl (0.9%) i.v
- Cricothyrotomy or coniotomy