Drugs for Respiratory Disorders: Part 3

Question 1

Anticholinergic drugs cause..

Answer 1

Bronchodilation

Question 2

Anticholinergic drugs are approved for ____ but used for _____

Answer 2

COPD

Asthma

Question 3

Two types of anticholinergic drugs

Answer 3

Ipratroprium (Atrovent)

Tiotroprium (Spiriva)

Question 4

Ipratroprium is used for..

Answer 4

Asthma

Question 5

Ipratroprium

Answer 5

Systemic effects minimal
Dry mouth
Avoid if peanut allergy

Question 6

Tiotropium is used for…

Answer 6

COPD

Question 7

Albuterol activates ____ while anticholinergics…

Answer 7

Sympathetic nervous system

Block parasympathetic nervous system

Question 8

Dual formulations of anticholinergic and albuterol

Answer 8

Combivent

DuoNeb

Question 9

Leukotrine modifiers

Answer 9

Inhibit leukotrines

Considered to be an allergy medication

Question 10

Leukotrines

Answer 10

Compounds that promote bronchoconstriction, mucus production and airway edema

Question 11

Mild intermittent asthma

Answer 11

Treated on PRN basis
Long-term control meds not needed
Beta2 manages occasional attacks

Question 12

When is a person moved up from moderate intermittent asthma?

Answer 12

When they are using albuterol more than twice a week

Question 13

Mild persistent asthma

Answer 13

Combo of long term control meds (steroids or long acting Beta 2) plus quick relief
Daily inhalation of anti inflammatory

Question 14

When would mild persistent asthma move up?

Answer 14

If using albuterol every day

Question 15

Moderate persistent asthma

Answer 15

Inhaled glucocorticoid - low dose, long acting beta 2, quick relief

Question 16

When would a moderate persistent asthma patient move up?

Answer 16

If they were still using albuterol every day

Question 17

Severe persistent asthma

Answer 17

Daily inhalation of high dose glucocorticoid plus long acting beta 2 agonist
Nebulizers, many MDIs

Question 18

Severe asthma exacerbations

Answer 18

Relieve obstruction and hypoxemia
Normalize lung function 
Repetitive inhalation of albuterol 
Give oxygen to keep O2 sats up 
Oral glucocorticoids x1 week after discharge

Question 19

Exercise induced bronchospasm

Answer 19

Bronchospasm secondary to loss of heat / water from lung

May inhale B2 immediately before exercise

Question 20

Mucolytics name

Answer 20

Acetylcysteine (Mucomyst)

Question 21

Mucomyst (acetylcysteine)

Answer 21

Liquefy and loosen thick mucous secretions - expectorate
Used as adjunct to bronchodilator
*Also antidote to Tylenol

Question 22

Mucomyst is a great drug for patients with…

Answer 22

Chronic bronchitis (but not used by itself)

Question 23

Will Tylenol still work with this drug? (Mucomyst)

Answer 23

Yes if in therapeutic doses