Drugs for Respiratory Disorders: Part 3 Flashcards
Anticholinergic drugs cause..
Bronchodilation
Anticholinergic drugs are approved for ____ but used for _____
COPD
Asthma
Two types of anticholinergic drugs
Ipratroprium (Atrovent)
Tiotroprium (Spiriva)
Ipratroprium is used for..
Asthma
Ipratroprium
Systemic effects minimal
Dry mouth
Avoid if peanut allergy
Tiotropium is used for…
COPD
Albuterol activates ____ while anticholinergics…
Sympathetic nervous system
Block parasympathetic nervous system
Dual formulations of anticholinergic and albuterol
Combivent
DuoNeb
Leukotrine modifiers
Inhibit leukotrines
Considered to be an allergy medication
Leukotrines
Compounds that promote bronchoconstriction, mucus production and airway edema
Mild intermittent asthma
Treated on PRN basis
Long-term control meds not needed
Beta2 manages occasional attacks
When is a person moved up from moderate intermittent asthma?
When they are using albuterol more than twice a week
Mild persistent asthma
Combo of long term control meds (steroids or long acting Beta 2) plus quick relief
Daily inhalation of anti inflammatory
When would mild persistent asthma move up?
If using albuterol every day
Moderate persistent asthma
Inhaled glucocorticoid - low dose, long acting beta 2, quick relief
When would a moderate persistent asthma patient move up?
If they were still using albuterol every day
Severe persistent asthma
Daily inhalation of high dose glucocorticoid plus long acting beta 2 agonist
Nebulizers, many MDIs
Severe asthma exacerbations
Relieve obstruction and hypoxemia Normalize lung function Repetitive inhalation of albuterol Give oxygen to keep O2 sats up Oral glucocorticoids x1 week after discharge
Exercise induced bronchospasm
Bronchospasm secondary to loss of heat / water from lung
May inhale B2 immediately before exercise
Mucolytics name
Acetylcysteine (Mucomyst)
Mucomyst (acetylcysteine)
Liquefy and loosen thick mucous secretions - expectorate
Used as adjunct to bronchodilator
*Also antidote to Tylenol
Mucomyst is a great drug for patients with…
Chronic bronchitis (but not used by itself)
Will Tylenol still work with this drug? (Mucomyst)
Yes if in therapeutic doses
