Analgesics: Part 3 Flashcards

1
Q

Strong opioid agonists

A
Fentanyl 
Meperidine (Demerol) 
Methadone
Heroin
Hydromorphone (Dilaudid)
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2
Q

Fentanyl methods of administration

A

Parenteral
Transdermal
Transmucosal

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3
Q

Methadone

A

Used for addiction and alcohol withdrawal, eases withdrawal symptoms but people can become addicted to it

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4
Q

Heroin is the most ______ and ______

A

Potent

Addictive

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5
Q

Moderate to strong opioid agonists

A
Codeine
Oxycodone
Hydrocodone
Propoxyphene
Tramadol
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6
Q

Oxycodone trade names

A

Oxycontin

Percocet

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7
Q

Hydrocodone trade names

A

Lortab, Norco

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8
Q

Propoxyphene trade names

A

Darvon, Darvocet

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9
Q

Tramadol trade names

A

Ultram

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10
Q

Codeine

A

Adverse effects are high, moderate pain reliever, used more as cough suppressant

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11
Q

Is Oxycodone or Hydrocodone stronger?

A

Oxycodone

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12
Q

Benefits of agonist-antagonist opioids

A

Low abuse potential

Less respiratory depression

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13
Q

Cona of agonist-antagonist opioids

A

Less powerful analgesic effects

Will cause withdrawal

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14
Q

Administration of opioids in the clinical setting should include..

A

Assessment of pain
Dosage determination
Routine schedule
Avoiding withdrawal

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15
Q

Are narcotics specifically dosed for the patient?

A

No

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16
Q

Development of physical addiction to opioids is extremely….

A

Rare

17
Q

How to administer opioids with discretion

A

Lowest effective doses
Shortest intervals possible
Withdrawal of opioids,,, nonopijoid analgesics

18
Q

Patient controlled analgesia can…

A

Provide comfort while minimizing sedation

19
Q

Patient controlled analgesia allows for…

A

Steady levels of opioid in system, rapid pain relief

20
Q

Opioid antagonists….

A

BLOCK the effects of opioid agonists

21
Q

Naloxone (Evzio)

A

First naloxone auto-injector
Outpatient use antagonist
Pro-active prescription for chronic opioid

22
Q

Glucocorticoids are used for..

A

Autoimmune disorders
Inflammatory conditions
Organ transplant patients
Cancer therapy

23
Q

Glucocorticoids: autoimmune disorders

A

Rheumatoid arthritis
Lupus
Ulcerative colitis

24
Q

Glucocorticoids: inflammatory conditions

A

Asthma

25
Q

Glucocorticoids are by far the best….

A

Anti-inflammatory drugs we have

26
Q

Glucocorticoids go after

A

Prostaglandins, interleukins, etc.

27
Q

Glucocorticoids are also great at

A

Immune suppression

28
Q

Adverse effects from glucocorticoids

A
Increased blood glucose
Abnormal fat deposits
Adrenal insufficiency 
Osteoporosis
Infection
Glucose intolerance
Cataracts / glaucoma
29
Q

Abnormal fat deposits: glucocorticoids

A

Moon face, buffalo hump

30
Q

When we give glucose corticoids, what are we doing to the adrenals?

A

We are replacing / adding to what they normally have so adrenals do not make steroids anymore

31
Q

Prolonged glucocorticoid therapy should ONLY be used for disorders that..

A

Are life threatening

Have the potential for long term disability

32
Q

Termination of long term therapy of glucocorticoids is by…

A

TAPER

33
Q

Glucocorticoids are usually given by a…

A

Burst and taper