Drugs affecting the ANS: Part 4 Flashcards

1
Q

Anticholinergic drugs

A

Inhibit the actions of acetylcholine

Parasympatholytics

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2
Q

Anticholinergic drugs effects

A

Decrease in GI motility
Decrease in salivation
Dilation of pupils
Increase in pulse rate

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3
Q

Adverse effects of anticholinergics

A

Constipation, dry mouth, blurred vision, tachycardia, urinary retention

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4
Q

Atropine (anticholinergic) affects…

A

Heart, exocrine glands, smooth muscle, eye, CNS

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5
Q

What does atropine cause?

A

Increased HR, decreased saliva production, relaxation of bronchi, mydriasis, CNS excitation

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6
Q

Therapeutic uses of atropine

A

Preanesthetic medication
Disorders of the eye
Bradycardia
Intestinal hypertonicity

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7
Q

Atropine: preanesthetic medication

A

Treatment for bradycardia - makes them mildly tachycardic

Decrease salivary secretions

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8
Q

Atropine: disorders of the eye

A

Eye exams, surgery

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9
Q

Atropine: bradycardia

A

pre-existing condition

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10
Q

Atropine: intestinal hypertonicity

A

Mild dysentery

Diverticulitis

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11
Q

Adverse effects of atropine

A
Xerostomia (dry mouth) 
Blurred vision 
Elevation of intraocular pressure
Urinary retention 
Constipation 
Tachycardia 
Asthma
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12
Q

Why does atropine cause asthma?

A

Because it is so dry - choke on secretions

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13
Q

Atropine drug interactions…

A

Medications that also cause muscarinic blockade can INCREASE the effects of atropine

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14
Q

Atropine drug interactions examples

A

Antihistamines (dry mouth)
Phenothiazine antipsychotics (horrendously drying)
Tricyclic antidepressants

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15
Q

Anticholinergic agents - Benztropine (Cogentin)

A

Decreases involuntary symptoms of Parkinsonism - tremors and muscle rigidity

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16
Q

Adverse effects of Benztropine (Cogentin)

A

Anticholinergic effects

Tachycardia / palpitations

17
Q

Overactive bladder 4 symptoms

A

Urinary urgency
Urinary frequency
Nocturia
Urge incontinence

18
Q

Anticholinergic drugs: overactive bladder

A

Block muscarinic receptors on bladder detrusor muscle… inhibit bladder contractions and urge to void

19
Q

Anticholinergics used for overactive bladder

A

Oxybutynin (Ditropan)

Tolterodine (Detrol)

20
Q

Anticholinergics used for overactive bladder should…

A

Cause sufficient blockade of muscarinic receptors without causing urinary retention (dosage just right)

21
Q

Side effects of Anticholinergics used for overactive bladder

A

Dry mouth
Constipation
Tachycardia

22
Q

Scopalomine is a…

A

Muscarinic antagonist, different because it crosses BBB

23
Q

Ipratroprium bromide (Atrovent)

A

Anticholinergic used to treat asthma or rhinitis caused by allergies

24
Q

Ipratroprium bromide (Atrovent) is administered by…

A

Inhalation

25
Q

Since Ipratroprium bromide (Atrovent) is administered by inhalation…

A

No dry mouth, blurred vision or constipation