Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Drugs for CHD: Part 2 > Flashcards

Drugs for CHD: Part 2 Flashcards

1
Q

Fibric acid medication name

A

Gemfibrozil (Lopid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fibric acid is the most effective for…
Little to no effect on….
Can raise..

A

Lowering VLDL and triglycerides
LDL
HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fibric acid increases..

A

Lipolysis and decreases the production of triglycerides by the liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adverse effects of fibric acid

A

GI upset, rashes, gallstones, myopathy, hepatotoxicity (increased if used with statin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ezetimibe (Zetia)

A

Blocks absorption of cholesterol in the small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Adverse effects of Ezetimibe (Zetia)

A

Generally well tolerated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ezetimibe (Zetia) drug interactions: statins

A

Increased risk of hepatotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ezetimibe (Zetia) drug interactions: fibrates

A

Increased risk of gallstones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Bile Acid sequestrants with zetia

A

Decrease efficacy of Zetia (if given at the same time)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Angina pectoris

A

Occurs when cardiac oxygen demand is greater than oxygen supply

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Oxygen demand is determined by…

A

Heart rate
Contractility
Preload
Afterload

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Oxygen supply is determined by

A

Myocaridial blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Preload

A

Pressure stretching of the ventricles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Afterload

A

Pressure that the heart has in order to expel blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Classic stable angina is AKA

A

Exertional angina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Classic stable angina

A

Occurs with predictable stress or exertion

17
Q

Unstable angina

A

Occurs with progressive severity

Unpredictable regarding stress / exertion

18
Q

Variant (Prinzmetal, vasospastic)

A

Occurs at rest (calcium channel blockers)

19
Q

Antianginal therapy

A 
Nitroglycerin 
Beta blocker
Calcium channel blockers
Oxygen 
Morphine
20
Q

What is the most significant anti-chest pain drug?

A

Nitroglycerin

21
Q

Morphine

A

Decreases anxiety of person and decrease oxygen demands of the heart

22
Q

Nitroglycerin (nitrates)

A

Improves the balance of myocardial oxygen supply and demand - relaxation of smooth muscle
Reduces myocardial ischemia

23
Q

Nitroglycerin: relaxation of smooth muscle

A

Venous dilation
Coronary vasodilation
Arterial vasodilation

24
Q

Adverse effects of nitrates

A

Headache
Orthostatic hypotension
Syncope
Reflex tachycardia

25
Q

What is the cause of Nitroglycerine’s adverse effects?

A

Does not only vasodilator to the heart but also to the whole body

26
Q

Syncope

A
  • feeling faint b/c blood is not able to be pushed to head when they stand up
27
Q

Nitrate drug interactions: hypotensive drugs

A

Caution with beta blockers, vasodilators, and calcium channel blockers

28
Q

Nitrate drug interactions: erectile dysfunction drugs

A

Absolutely contraindicated with Viagra, Cialis and Levitra
(Also vasodilate)
-Tolerance can develop

29
Q

Nitroglycerine is given…

A

Sublingually (b/c of extensive first pass effect)

30
Q

Nitroglycerin must be stored…

A

Away from heat, humidity and light

31
Q

Nitroglycerin should be replaced…

A

Every 6 months to maintain potency

32
Q

Nitroglycerin can be given…

A

Every 5 minutes

Nothing beyond 3 (take one, sit down and see if chest pain gets better)

33
Q

Ntg (Nitro-dur) transdermal

A

Apply patch to clean, dry skin

Rotate to prevent skin irritation

34
Q

Tolerance to nitroglycerin can be prevented by…

A

Removing patch nightly (8-12 hour nitrate free period)

35
Q

When you use paste, you always have to…

A

Have gloves on

36
Q

Beta blockers

A

Reduce chest pain by decreasing heart rate and cardiac contractility (reduce oxygen demand of the heart)

37
Q

Adverse effects of beta blockers

A

Bradycardia
Dizziness
Orthostatic hypotension
GI upset

38
Q

Calcium channel blockers..

A

Relax vascular smooth muscle
Relax coronary artery spasm
Relax peripheral arterioles
Slows AV conduction

39
Q

Adverse effects of calcium channel blockers

A

Bradycardia
Orthostatic hypotension
Constipation
Reflex tachycardia

Pharmacology (38 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions