Drugs for infection: Part 3

Question 1

Vancomycin

Answer 1

Inhibitor of cell wall synthesis

Question 2

Vancomycin is a potentially toxic drug, so…

Answer 2

It is used only for serious infections

Question 3

Vancomycin uses

Answer 3

MRSA

Question 4

Vancomycin was brought out for…

Answer 4

MRSA

Question 5

What can possibly be used to treat VISA?

Answer 5

5th gen cephalosporins

Question 6

________ and vancomycin will be used together

Answer 6

Aminoglycosides

Question 7

Adverse effects of vancomycin

Answer 7

Bladder pain 
Bloody urine 
Muscle cramps
Fever
Ototoxicity 
Red man syndrome

Question 8

Red man syndrome

Answer 8

Rash affecting the face, neck and upper torso
Hypotension
Nausea and vomiting

Question 9

Red man syndrome is caused by…

Answer 9

Infusing vancomycin too quickly

Question 10

Daptomycin mechanism of action

Answer 10

Binds to bacterial membrane = depolarization of membrane potential

Question 11

Uses of daptomycin

Answer 11

Septicemia due to staphylococcus aureus
Complicated skin infections
Ineffective endocarditic due to MRSA

Question 12

Daptomycin adverse effects

Answer 12

Hypertension 
Hypotension 
Anemia
Numbness & tingling
Dizziness
Insomnia
Pain with urination

Question 13

Metronidazole (Flagyl) treats…

Answer 13

Protozoal infections, infections caused by obligate anaerobes, helicobacter pylori

Question 14

Adverse effects of Metronidazole

Answer 14

Neurotoxicity
Allergy
Superinfections

Question 15

Metronidazole is used for…

Answer 15

C diff
Prophylaxis in surgical procedures
In combo with drugs active against aerobic bacteria