Cholinoceptor blockers Flashcards
The first choice of drug to reverse organophosphate poisoning to address the muscarinic excess
atropine
a tertiary amine, can cross BBB
___ is mydriatic, cycloplegic
atropine
[SE]
sandy eyes or dry eyes due to reduced lacrimal secretion
atropine
Used in parkinsons disease to reduce the excess cholinergic activity secondary to the deficient dopaminergic activity in the basal ganglia-striatum system
benztropine
What are the muscarinic antagonists for parkinsonism?
Triphexyphenidyl
Benztropine
Biperiden
prevents vagal-stimulated bronchoconstriction
ipatropium
this m receptor antagonist cant cross the BBB
glycopyrronium
[Cholinergic antagonist, muscarinic]
antagonize histamine and serotonin
scopolamine
[Cholinergic antagonist, muscarinic]
used for motion sickness
scopolamine
[Cholinergic antagonist, muscarinic]
used in inflammatory bowel syndrome, can cause increased intraocular pressure
quaternary amine structure
dicyclomine
Similar: hyoscyamine
also known as dicycloverine
[Cholinergic antagonist, muscarinic, M3]
reduce detrusor muscle tone; treatment for urge incontienence, post-operative spasm
oxybutynin
[what are the contraindications to muscarinic blockers?
- cautious use in infant
- acute angle-closure glaucoma
- benign prostatic hyperplasia
This is a competitive antagonist at nicotinic acetylcholine receptors of both sympathetic and parasympathetic autonomic ganglia
ganglion blockers
hexamethonium
[Cholinergic antagonist, nicotinic]
___ an obsolete treatment for hypertensive emergencies.
hexamethonium
[Neuromuscular blockers]
Examples on NONDEPOLARIZING NMB
Atracurium
Pancuronium
Tubucurarine
Vecuronium
