Asthma Drugs

Question 1

The drug of choice for acute asthma attacks

Answer 1

beta 2 selective agonist (short acting)

Salbutamol/Albuterol

Question 2

This drug class can precipitate arrhythmias in patients with concurrent COPD and heart disease

Answer 2

Beta 2 selective agonist (short acting)

Question 3

Terbutaline is what drug class?

Answer 3

Beta 2 selective agonist (short acting) can be given inhalational, PO, IV

Question 4

DOC for asthma prophylaxis

Answer 4

beta 2 selective (long acting)

Question 5

Cite examples of long acting SABA

Answer 5

Formoterol
Arformoterol
Bambuterol
Cleneterol
Vilanterol
Indacaterol
Olodaterol
Salmeterol

Question 6

Asthma drug that blocks muscarinic receptors in bronchial smooth muscle

Answer 6

muscarinic receptor antagonist

Question 7

This drug class has no effect of chronic inflammation aspect of bronchial asthma

Answer 7

Antimuscarinic receptors

Question 8

[Muscarinic receptor antagonist]

does not cross the BBB, few central effects

Answer 8

Glycopyrronium

Question 9

[Muscarinic receptor antagonist]

used as anti-spasmodic, reduce salivation with some anesthetics

Answer 9

glycopyrronium

Question 10

This drug class has a MOA of phosphodiesterase inhibition and adenosine receptor antagonist leading to bronchodilation

Answer 10

Theophylline

Question 11

This drug is used as prophylaxis against nocturnal attacks

Answer 11

Theophylline

Question 12

Drug used for intermittent claudication

Answer 12

pentoxyfylline

Question 13

What is the antidote for methylxanthine overdose?

Answer 13

betablockers

Question 14

Examples of Mast cell stabilizer

Answer 14

1. Cromolyn
2. Nedocromil
3. Lodoxamide

Question 15

Anti asthma drug but can also induce cough at SE

Answer 15

Mast cell stabilizers

Question 16

Off label use of mast cell stabilizers

Answer 16

1. Food allergy

2. IBD

Question 17

What is the drug of choice for asthma prophylaxis?

Answer 17

Fluticasone

Question 18

What is the first line treatment for moderate to severe BA, COPD, AR,

Answer 18

Corticosteroid

Question 19

What is the drug of choice for status asthmaticus?

Answer 19

1. IV prednisolone

2. Hydrocortisone

Question 20

What is the active metabolite of prednisone?

Answer 20

prednisolone

Question 21

Among the corticosteroids, which has the lowest systemic steroid toxicity?

Answer 21

Ciclesonide

Question 22

Cite example of lipooxygenase inhibitor (5-lipooxygenase)

Answer 22

Zileuton

Question 23

What are the drug used for exercise-, antigen-, and aspirin-induced bronchospasm?

Answer 23

Zileuton (LT synthesis inhibitor), LTRA (-lukasts)

Question 24

Drug class that can cause transaminitis

Answer 24

Zilueton

Question 25

Drug class that has no bronchodilator action and not recommended for acute BA attacks

Answer 25

Zileuton (Lipooxygenase inhibitors) and LTRA (-lukasts)

Question 26

Cite examples of LTRA?

Answer 26

1. Montelukast 2. Pranlukast 3. Zafirlukast

Question 27

Montelukast block what receptor?

Answer 27

Cysteinyl leukotriene-1 for LTC4, LTD4, LTE4

Question 28

Antiasthma drugs that can cause Churg-Strauss Syndome

Answer 28

LTRA (-lukasts)

Question 29

Anti-IgE antibody that binds IgE on Mast cells

Answer 29

Omalizumab

Question 30

What is the antidote for acetaminophen toxicity?

Answer 30

NAC

Question 31

Drug for cough that is an expectorant by acting as an irritant to gastric vagal receptors

Answer 31

Guiafenesin

Question 32

Cite examples of antitussive

Answer 32

1. Codeine | 2. Dextromethorphan

Question 33

Drug thatn can be used for painful cough of neoplasia or pleural disease, epiglottitis, in hemoptysis has no antibacterial role

Answer 33

Antitussives

Question 34

Antitussive that has no addictive potential, no analgesic effect, less constipation, inhibition of mucociliary clearance

Answer 34

Dextromethorphan

Question 35

Example of non-opioid antitussive; acts through the receptors in the brainstem to inhibit cough

Answer 35

Butamirate citrate

Question 36

Peripherally acting antitussive; inhibits the afferent pathway that generate cough reflex

Answer 36

levodropropizine

Question 37

inhibits PDE III and inhibits CCB, potent anti-COX2 activity

Answer 37

Vitex negundo (Lagundi)