Chapter 7.6 Hypersensitive Reactions Flashcards
Define Allergies
Immune responses to normally harmless substances, found in 8-10% (1 in every 5) Americans. They are hypersensitivities to substances that ordinarily would do no harm to the body.
What is an immediate allergic response?
It can occur within seconds of contact with the antigen. This response is caused by antibodies known as IgE.
Describe asthma
Allergic reaction that results in airway obstruction.
Describe anaphylactic shock
Most severe type of allergic reaction; it can be lethal. It is a sudden life threatening drop in blood pressure due to increased permeability of the capillaries by histamine.
Describe delayed allergic response
It is initiated by memory T cells at the site of the allergen contact in the body.
Describe xenotransplantation
Transplanting animal (or lab made) organs into humans
Define autoimmune disorders
The powerful weapons of the immune system become unleased against normal body cells and proteins
Define rhuematoid arthritis
Macrophages, T and B cells target the synovial membranes of synovial joints. Genetic predisposition, possible role of pathogens
Define systemic Lupus Erythematosus
Development of antibodies in one owns DNA, can include arthritic component but can also affect many other systems
Define Deficient immune disorders
Conditions that lead to a drop in immune response
Define poorly controlled diabetes
Due to damage to small blood vessels, interfering with the delivery of blood components, will generally show poor resistance to infections
Define Lymphoma
Any cancers of lymphocytes; functions are greatly impaired or destroyed
AIDS
Acquired immune deficiency syndrom-from HIV (human immunodeficiency virus) which attacks macrophages and helper T cells, patients usually eventually expire from opportunistic infections or rare forms of cancer
What are the infectious diseases that can overcome our defenses?
Virulence:refers to the relative ability of a pathogen to cause serious disease,
What are the patterns of occurrence?
- Sporadic: irregular and limited outbreaks
- Endemic: more or less continuous
- Epidemic: outbreak that surpasses the predicted rate
- Pandemic: when epidemics break out in several regions around the world in a given time span