Chapter 16 and 17 course packet Flashcards
The first 22 pairs of sex chromosomes are
Autosomes
Female sex chromosomes are truly what?
Homologous xx
What chromosomes do the males have?
X and a very short Y
What is Sry?
Sex-determining Region of the Y chromosome
One gene on the Y chromosome is called?
Sry
When does Sry become active?
When the embryo is about 6 weeks old
Up to about 6 weeks, both male and female embryos are what?
Anatomnically identical
If the Sry is present in only XY chromosomes what happens?
Germ cells and the cells immediately around them begin to develop into testes at about 7 weeks
If the Sry is absent then what?
Cells begin to develop into ovaries
The cells that become the male gonad (testes), begin to secrete and release what
Testosterone
What does the releasing of testosterone signal
The further developlment of the male sexual organs in the embryo & the male secondary sexual traits at puberty
The cells that become the female gonad (ovary), begin to secrete and release what
Estrogen & eventually progesterone
What does the releasing of estrogen and progesterone signal
The further development of the female sexual organs in the embryo & the female secondary sexual traits as puberty
What are the 5 male reproductive organs
1) 2 testes
2) 2 epididymis
3) 2 Vas deferens
4) 2 Ejaculatory ducts
5) Penis
3 Male accessory glands
1) 2 Seminal vesicle
2) Prostate gland
3) 2 Bulbourethral gland
Function of testes
Seminiferous tubules: sperm production; Leydig cells: sex hormones
Function of Epididymis
Sperm maturation site; & further from the testis, sperm storage
Function of Vas deferens
Rapid transport of sperm
Function of Ejaculatory duct
After seminal vesicle, conduction of sperm to the penis
Function of the penis
Organ of sexual intercourse
Function of the seminal vesicle
Secretion of fructose & prostaglandins, a large part of semen
Function of Prostate gland
Secretion of buffers and other substances that become part of semen
Function of the bulbourethral gland
Secretion of lubricating mucus
Where can the Leydig cells be found
Found between seminiferous tubules of the testes
Fertile males operate w/in what
A narrow range of circulating male hormones
The meiosis is easily seen when
Looking at a cross-section of a seminiferous tubule & moving from the outside in
What is the order of the cell (genome) for meiosis
1) Spermatogonium (2n)
2) Primary spermatocyte (2n)
3) Secondary spermatocyte (n, but still replicated DNA)
4) Early spermatids (n)
5) Late spermatids (n)
6) Immature sperm (n)
7) Mature sperm (n)
What is the meiotic stage for Spermatogonium
Mitosis
What is the meiotic stage for primary spermatocyte
Meiosis 1
What is the meiotic stage for Secondary spermatocyte
Meiosis 2
Location of Spermatogonium
Outermost cells within the tubule walls
Location of primary spermatocyte
Cells just inside the spermatogonia
Location of secondary spermatocyte
Numerous smaller cells in the mid-wall
Location of early spermatids
Yet smaller cells nearer to the cavity
Location of late spermatids
Inner cells still attached to the tubule wall
Location of immature sperm
Sperm cells now released into the cavity start to head to the epididymis
Location of mature sperm
In the epididymis, furthest from the testes
Included structures of a sperm
1) Acrosome
2) Head
3) Midpiece
4) Tail
Acrosome of a sperm is
Enzyme-rich cap enables sperm to penetrate all the “stuff” around ovum
Head of a spermis
Important, contains haploid DNA
Midpiece of a sperm is
Mitochondria supplying ATP’s for microtubule movement
Tail of a sperm is
Microtubules propel sperm to egg
The 5 female reproductive organs are
1) 2 Ovaries
2) 2 Oviducts
3) Uterus
4) Cervix
5) Vagina
Function of the ovaries
Oocyte production & maturation; estrogen & progesterone secretion
Function of the oviducts
Conduction of oocyte from ovary to uterus, usual site of fertilization
Function of the uterus
Chamber of embryo & fetal development, myometrium & endometrium
Function of the cervix
Narrowed entry in uterus, secretes mucus which enhances sperm movement into uterus & forms a bacterial barrier after fertilization
Function of the vagina
Organ of sexual intercourse, birth canal
Estrogen is secreted by
The ovaries
Both FSH & LH are involved in negative feedback loops just like in the male, except the females hypothalamus is sensing
Circulating blood levels of estrogen & progesterone
During the menstrual cycle while the GnRH from the hypothalamus stimulates the anterior pituitary to secrete FSH & LH, there is a specific
Mid-cycle surge of LH that triggers ovulation at about day 14 of the cycle
What are the 3 phases of menstrual cycle
1) Follicular phase
2) Ovulation
3) Luteal phase
Follicular phase is
Days 1-5 Endometrium breaks down, menstruation; low estrogen, progesterone, FSH LH
Days 6-13 Hypothalamus: increase GnRH, anterior pituitary: increase FSH & LH, to maturation of one follicle to estrogen increase to gradual thickening of endometrium
Day 13 & midcycle surge of LH
Ovulation phase
Day 14 Secondary oocyte relseased from ovary; FSH & LH decrease; estrogen stabilizes, progesterone begins to increase
The luteal phase is
Day 15-28 Corpus luteum established, estrogen secretion is maintained & progesterone increases, Endometrium thickens & ripens for implantation of fertilized egg
If no pregnancy occurs during the phases what happens
Back to day 1 as corpus luteum degenerates, decrease of estrogen & progesterone levels
In the female fetus several million primary oocytes will enter
Meiosis 1 but stop before meiosis 1 is complete
At birth, primary oocytes number is about what
2 million
At age 7, only how much oocytes remain
About 300,000 remain still in a state of arrested meiosis 1 (prophase 1)
At puberty, meiosis will resume what at a time
One oocyte at a time starting with the first menstrual cycle
How many oocytes will develop and be released until menopause
About 400-500
What is the order for the cell (genome)
1) Primary oocyte in primordial follicle
2) Primary oocyte in maturing follicle
3) Secondary oocyte in mature follicle
4) Secondary oocyte
5) Secondary oocyte will actually not undergo meiosis 2 until sperm penetrates into cytoplasm
Meiotic stage for Primary oocyte in primordial follicle
Arrested meiosis 1
Meiotic stage for Primary oocyte in maturing follicle
Arrested meiosis 1
Meiotic stage for Secondary oocyte in mature follicle
Only meiosis 1 completed
Meiotic stage for secondary oocyte
Only meiosis 1 completed
Characteristic of primary oocyte in primordial follicle
Very few follicular cells surround oocyte
Characteristic of primary oocyte in maturing follicle
Zona pellucida then antrum develops
Characterisic of secondary oocyte in mature follicle
1st polar body formed, follicle protrudes slightly from ovarian surface
Characteristic of secondary oocyte
Ovulates when LH triggers follicle ruptures
When are the 2nd & 3rd polar bodies formed
When the sperm penetrates into the cytoplasm
What is required for male fertilization
High count of motile/functional sperm
What is required for female fertilization
Functional menstrual cycles w/ regular ovulation, open oviducts for conductiong both egg and sperm, and ovulations timed with monthly endometrial thickening
What are the 3 birth control aspects
1) Correct & consistent use of most contraceptive methods results in a low risk of pregnancy
2) Contraceptives pose little risk to a user’s health, although personal risk factors should influence personal choice
3) Half of all pregnancies are unintended (~3 million each year)
The hypothalamus senses what?
blood vessels of testosterone & inhibin
If blood levels are LOW what happens
If blood levels low, hypothalamus will secrete GnRH
The anterior pituitary secretes what into the blood stream
Anterior pituitary secretes FSH & LH into blood stream
Which of the male organs are set in motion
Testes “set in motion”
If testes or overstimulated what happens
If testes are overstimulated, sertoli cells will secrete inhibin for HIGH sperm counts
One the hypothalamus senses the low blood levels what happens next
Then turn GnRH down decreasing FSH & LH secretion which then decreases testosterone secretion & sperm production by the testes