Chapter 25: Blood And Lymph Infections Flashcards

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1
Q

An enlarged tender lymph node
Characteristic of the plague and some STDs

A

Bubo

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2
Q

Uncontrolled release of Pro-inflammatory cytokines

Causes blood vessel leakage and may lead to shock

A

Cytokine storm

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3
Q

Condition in which clots form in small blood vessels throughout the body

Causing organ failure due to lack of O² and bleeding due to shortage of clotting proteins

A

Disseminated intravascular coagulation (DIC)

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4
Q

Inflammation of the heart valves or lining of the heart chambers resulting from infection

A

Infective Endocarditis

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5
Q

Lymphangitis

A

Inflammation of lymphatic vessels

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6
Q

Sudden recurrence of worsening symptoms as seen in the cycle of chills, fever, and sweat from malaria

A

Paroxysm

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7
Q

Purple spots on the skin and mucos membrane caused by blood leakage from small blood vessels

A

Petechiae

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8
Q

Acute illness caused by an inflammation response that results when pathogens or their products circulate in the blood system

A

Sepsis

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9
Q

Range of effects that results from a systemic inflammatory response to a blood steam infection or circulating endotoxin; effects include fever, drop in blood pressure, and DIC

A

Septic shock

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10
Q

An infection of 1 or more heart valves or other surfaces of endocradium.

Predisposing factors

Indwelling catheters
Underlying heart defects / damaged valves

A

Infective endocarditis

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11
Q

Endocarditis causative agent(s)

A

S. aureus, S. epidermidis, enterococci, & variety of Streptococcus

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12
Q

Life threatening overreaction of the body’s normally beneficial inflammatory response

A

Sepsis

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13
Q

Starts from an infection in body tissues, macrophages release Pro-inflammatory cytokines in response to bacterial products

Complement activated

Uncontrolled inflammatory response

Leading to shock, hypoxia, and organ failure

A

Sepsis

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14
Q

Most common type of plague

Results for being bitten by infected flea

High fever and tender lymph nodes called Buboes

With out treatment it will worsen

A

Bubonic plague

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15
Q

This type of plague

Endotoxins from bacteria result in

High fever, shock, disseminated intravascular coagulation (DIC)

Leading to Red or Black patches

Gangrene of fingers and toes

A

Septicemic plague

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16
Q

This plague

Inhalation of respiratory droplets from infected individual or

When organsims in blood enter the lungs

A

Pneumonic plague

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17
Q

Yersinia pestis causes

A

Plague

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18
Q

Enlarged lymph nodes and
Rash called: Erythema margins (Bullseye) in 70-80%

This rash may also appear after a bite from a tick that doesn’t transmit this disease

Also, Headache, Muscle ache, fever , Flu-like malaise

A

Lyme disease

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19
Q

3 - 10 weeks after infection

Rashes varios body parts
Facial paralysis, sever headache, pain moving eyes

Rare cases impaired electrical conduction of heart

A

Borrelia burgdorferi

Lymes disease

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20
Q

Borrelia burgdorferi causes

A

Lymes disease

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21
Q

Borrelia burgdorferi is Spirochete morphology

What is unique about its chromosomes

A

Linera shapped Presents multiple copies

Also, many plasmids

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22
Q

Lipopolysaccharide is

A

Endotoxin

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23
Q

Black legged deer tick causes

A

Lymes disease

B. burgdorferi

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24
Q

Which stage of the deer tick life cycle is most responsible for transmitting lymes disease

A

Nymph

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25
Q

Early localized infection
Bulls eye rash

Early Disseminated infection
Heart and nervous system involvement

Late persistent infection
Chronic arthritis & nervous system impairment

A

Borrelia burgdorferi
Lymes disease

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26
Q

This organism causes 95% of seafood associated deaths in the US

A

Vibro vulnificus

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27
Q

Most cases of this are in the Gulf Coast Region but are expanding due to global warming

A

Vibro vulnificus

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28
Q

Ingested this Bacterial disease is usually mild

People with high iron levels, liver disease, immunodeficiency

Experience bloodstream infection

Fever, chills, skin blisters, sepis & shock, which is often fatal

A

Vibro vulnificus

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29
Q

Broken skin entry

Blood filled skin blisters called BULLAE develop, progressing to cellulitis and Necrotizing fasciitis

A

Vibro vulnificus

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30
Q

Zoonotic disease transmitted multiple ways.

Direct contact, arthropod bites, ingested, inhaled.

Potential bioterrorism Category A

A

Francisella tularenis

Tularemia (Rabbit/ Deer fly fever)

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31
Q

Ulcerglandular is the most common type of Symptoms of this disease

Results in an Ulcer at point of contact
Regional enlarged lymph nodes
Fever, headache, and chills

A

Tularemia
(Rabbit/ Deer fly fever)

Francisella tularensis

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32
Q

This blood and lymph bacterial infection has 4 causative agents

B. abortus (cattle)
B. canis (dogs)
B. melitenis (goats / sheep)
B. suis (pigs)

A

Brucellosis

Undulat fever / Bangs Disease

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33
Q

Like Tularemia, this Bacteria is a bioterrorism weapon Category B

A

Brucella

Undulant fever / Bangs disease

34
Q

Fevers come and go with this disease.

Most people recover in 2 months without treatment but some develop chronic illness

A

Brucella

Undulat fever / Bangs Disease

35
Q

An attenuated vaccine controls this disease in domestic animals

A

Brucellosis

Undulat fever/ Bangs Disease

36
Q

Osteomyelitis is a rare but serious complication

Most deaths occur due to
Endocarditis or meningitis

A

Brucellosis

Undulat fever/ Bangs Disease

37
Q

Plague is endemic among rodents and is transmitted to humans via…

A

Flea bites

38
Q

____ is the most common vector born illness in US

A

Lymes disease

39
Q

_____ infections may cause several diseases, particularly in people with High Iron / predisposing conditions

A

Vibro vulnificus

40
Q

_____ is a disease of wild animals transmitted to humans via exposure to their blood or tissues, or biting ticks / insects

A

Tularemia

41
Q

____ is most commonly a disease of domestic animals, transmitted to humans when individuals handle the animals’ flesh or drink unpasteurized milk

A

Brucellosis

42
Q

Mononucleosis, Ebola, and Marburg are transmitted via…

A

Body fluids

43
Q

Yellow fever, dengue and sever dengue, chikungunya, and Zika are transmitted via

A

Mosquitoes

44
Q

Arthropod-borne RNA virus, carried by vectors such as mosquitoes

A

Arbovirus

45
Q

This viral disease is sometimes mistaken for leukemia

A

Infectious Mononucleosis

Mono / kissing disease

46
Q

Epstein-Barr virus causes

A

Infectious mononucleosis

47
Q

Infectious mononucleosis from (Epstein-Barr virus) infects these cells

A

B lymphocytes

48
Q

(Latent or Productive) is the most common form of Infections Mononucleosis (Epstein-Barr virus)

A

Latent

49
Q

Pathogenesis

Productive infection of epithelial cells of throat and salvia ducts,

Productive and latent infection of B lymphocytes

Hemmorage from ruptured spleen, rare but serious

Spread by saliva

Life Long reoccurring shedding of virus of latent infected individuals

This VIRAL INFECTION OF THE BLOOD AND LYMPH

A

Infectious mononucleosis

Epstein-Barr virus

50
Q

Ebola & Marburg virus both have a virus that shares their name

Which family do they belong to

A

Filovirdae

51
Q

Pathogenesis

Little is known

Infect phagocytes as well as other cells

Infection interfere with innate and adaptive immune response.

Allowing virus to replicate quickly

Blood clotting disrupted leading to Hemorrhaging

A

Ebola & Marburg disease

52
Q

Fruit bats in Africa are the likely reservoir for this Virus of the Blood and lymph system

But it is unknown

A

Ebola & Marburg

53
Q

Is there a vaccine for Ebola and Marburg

A

Yes, but it’s experimental

54
Q

Symptoms of this Viral Blood and Lymph infection

Black vomit & jaundice

A

Yellow fever

Family flavivirdea

Arbovirus from mosquito bites

55
Q

Petechiae (Small purple spots on skin and mucous membranes)

Travles to the liver (jaundice)

Kidney failure

Pathogenesis of….

A

Yellow fever

56
Q

Main reservoir for this Viral Blood infection is Primates in South America & Africa

A

Yellow fever

57
Q

Does yellow fever have a vaccine

A

Yes

58
Q

This arbovirus is aka Break Bone fever

A

Dengue

59
Q

Causative agents

DENV1, DENV2, DENV3, DENV4

A

Dengue and sever dengue

60
Q

Details of the pathogenesis are not well understood because there are no animal models for the disease

A

Dengue

61
Q

A phenomenon in which previous formed antibodies of 1 serotype of a virus facilitate infection of a different serotype (ADE)

Is the pathogenesis of this disease

A

Sever dengue

62
Q

The critical feature of ____ is plasma leakage caused by increased blood vessel permeability

Viral infection

A

Sever dengue

63
Q

Aedas aegypti is the cause of these two viral infections

A

Dengue & yellow fever

64
Q

This viral disease causes bad posture in African people

A

Chikungunya

65
Q

Chikungunya Is a virus that causes bad posture.

It is from this family

A

Togaviridae

66
Q

This viral disease causes Microcephaly

A

Zika

67
Q

Virus enter the body

Fever, rash joint pain, RED EYES

A

Zika virus

68
Q

Can zika be spread by sex

A

Yes

69
Q

In general Asprins and non-steroidal pain pills should be avoided during a viral infection

T or F

A

T

70
Q

This virus can involve damage to the fetus

A

Zika virus

71
Q

____ newly emerging disease that, like dengue, causes sever joint pain

A

Chikungunya

72
Q

____ is the most common vector born virus in the world, similar to, but milder than, yellow fever

A

Dengue

73
Q

This is a protozoan caused infection of Blood and Lymph

A

Malaria

74
Q

Signs

Reconcurrent cycles of intense chills and fevers alternating with feeling healthy

Causative agent

5 species of Plasmodium

A

Malaria

75
Q

Malaria can be transmitted person to person or by bite of infected Anopheles mosquitoes

T or F

A

T

76
Q

Treatment for this protozoan disease is ACTs

A

Malaria

77
Q

____ is often spread from normal microbiota in people with indwelling catheters or heart abnormalities IV drug use

A

Infective endocarditis

78
Q

____ is an infectious-induced systemic inflammatory response, common in health care illnesss, underlying health issue often to blame

A

Sepsis

79
Q

___ is transmitted to humans from fleas.

____ is transmitted from person to person via aerosols

If bacteria enters the bloodstream, _____ may occur

A

Bubonic plague

Pneumonic plague

Septicemic plague

80
Q

Aedes mosquito & monkeys

The disease involves heart and blood vessels,fever, jaundice, hemorrhages

Attenuated vaccine available

Viral

A

Yellow fever

81
Q

Dengue vaccine is available for whom

A

People that already had dengue

To prevent 2ndary more serious infection

82
Q

Erythema margins are associated with..

A

Lymes disease

Bordetella burgdorferi