Chapter 25: Blood And Lymph Infections Flashcards
An enlarged tender lymph node
Characteristic of the plague and some STDs
Bubo
Uncontrolled release of Pro-inflammatory cytokines
Causes blood vessel leakage and may lead to shock
Cytokine storm
Condition in which clots form in small blood vessels throughout the body
Causing organ failure due to lack of O² and bleeding due to shortage of clotting proteins
Disseminated intravascular coagulation (DIC)
Inflammation of the heart valves or lining of the heart chambers resulting from infection
Infective Endocarditis
Lymphangitis
Inflammation of lymphatic vessels
Sudden recurrence of worsening symptoms as seen in the cycle of chills, fever, and sweat from malaria
Paroxysm
Purple spots on the skin and mucos membrane caused by blood leakage from small blood vessels
Petechiae
Acute illness caused by an inflammation response that results when pathogens or their products circulate in the blood system
Sepsis
Range of effects that results from a systemic inflammatory response to a blood steam infection or circulating endotoxin; effects include fever, drop in blood pressure, and DIC
Septic shock
An infection of 1 or more heart valves or other surfaces of endocradium.
Predisposing factors
Indwelling catheters
Underlying heart defects / damaged valves
Infective endocarditis
Endocarditis causative agent(s)
S. aureus, S. epidermidis, enterococci, & variety of Streptococcus
Life threatening overreaction of the body’s normally beneficial inflammatory response
Sepsis
Starts from an infection in body tissues, macrophages release Pro-inflammatory cytokines in response to bacterial products
Complement activated
Uncontrolled inflammatory response
Leading to shock, hypoxia, and organ failure
Sepsis
Most common type of plague
Results for being bitten by infected flea
High fever and tender lymph nodes called Buboes
With out treatment it will worsen
Bubonic plague
This type of plague
Endotoxins from bacteria result in
High fever, shock, disseminated intravascular coagulation (DIC)
Leading to Red or Black patches
Gangrene of fingers and toes
Septicemic plague
This plague
Inhalation of respiratory droplets from infected individual or
When organsims in blood enter the lungs
Pneumonic plague
Yersinia pestis causes
Plague
Enlarged lymph nodes and
Rash called: Erythema margins (Bullseye) in 70-80%
This rash may also appear after a bite from a tick that doesn’t transmit this disease
Also, Headache, Muscle ache, fever , Flu-like malaise
Lyme disease
3 - 10 weeks after infection
Rashes varios body parts
Facial paralysis, sever headache, pain moving eyes
Rare cases impaired electrical conduction of heart
Borrelia burgdorferi
Lymes disease
Borrelia burgdorferi causes
Lymes disease
Borrelia burgdorferi is Spirochete morphology
What is unique about its chromosomes
Linera shapped Presents multiple copies
Also, many plasmids
Lipopolysaccharide is
Endotoxin
Black legged deer tick causes
Lymes disease
B. burgdorferi
Which stage of the deer tick life cycle is most responsible for transmitting lymes disease
Nymph
Early localized infection
Bulls eye rash
Early Disseminated infection
Heart and nervous system involvement
Late persistent infection
Chronic arthritis & nervous system impairment
Borrelia burgdorferi
Lymes disease
This organism causes 95% of seafood associated deaths in the US
Vibro vulnificus
Most cases of this are in the Gulf Coast Region but are expanding due to global warming
Vibro vulnificus
Ingested this Bacterial disease is usually mild
People with high iron levels, liver disease, immunodeficiency
Experience bloodstream infection
Fever, chills, skin blisters, sepis & shock, which is often fatal
Vibro vulnificus
Broken skin entry
Blood filled skin blisters called BULLAE develop, progressing to cellulitis and Necrotizing fasciitis
Vibro vulnificus
Zoonotic disease transmitted multiple ways.
Direct contact, arthropod bites, ingested, inhaled.
Potential bioterrorism Category A
Francisella tularenis
Tularemia (Rabbit/ Deer fly fever)
Ulcerglandular is the most common type of Symptoms of this disease
Results in an Ulcer at point of contact
Regional enlarged lymph nodes
Fever, headache, and chills
Tularemia
(Rabbit/ Deer fly fever)
Francisella tularensis
This blood and lymph bacterial infection has 4 causative agents
B. abortus (cattle)
B. canis (dogs)
B. melitenis (goats / sheep)
B. suis (pigs)
Brucellosis
Undulat fever / Bangs Disease