Chapter 23: Wound Infection Flashcards
Wound healing =
Granulation tissue
Wound ___ at site seals off wound
Abcesses
Coagulase causes plasma to clot
S epidermidis
S aureus
Which are their coagulase status
S epidermidis: Coagulase Negative
S aureus: Coagulase Positive
Staphylococcus in general causes this production
Pus production
S aureus Virulence factor name…
Attaches to fibrin, fibrogen, and plastic devices
Clumping factor
S aureus Virulence factors
Makes holes in host cell membrane
A-Toxin
S aureus Virulence factors
Kills neutrophils or degranulates them
Leukocidin
What does Protein A in staphylococcus do
Covers the fc portion of the antibody, Hiding it from phagocytes
This Streptococcus is a “ Flesh Eater”
Necrotizing fasciitis
Streptococcus pyogenes
In Streptococcus pyogenes
Pyrogenic exotoxin A “super antigen” causes
Exotoxin B causes
Streptococcal toxic shock
Protease that destroys tissue proteins
How is Necrotizing fasciitis dealt with in medical treatments
Surgery
This skin infection most common in hospitals is the hardest to treat in burn victims
Pseudomonas aeruginosa
Pseudomonas aeruginosa produces
Exoenzyme S which….
Exotoxin A which….
Exoenzyme S: Destroys Cell Membrane
Exotoxin A: Stops host cell protein synthesis
To treat Pseudomonas aeruginosa skin infection what is done
Remove damaged infected tissue
Clostridium tetani causes this Skin Infection
Tetanus (Lock Jaw)
Pupils lose response to light and toxins prevents inhibitory neurons from functioning
Is this Skin Infection caused by this disease
Tetanus
Clostridium tetani
TIG and vaccines are ways to fight against this Bacterial skin infection
Tetanus
Clostridium tetani
Clostridium perfinges releases “a-toxin” which kills leukocytes and normal tissue. In this Bacterial Skin Infection
Gas gangrene
Clostridial myonecrosis
Actinomycosis is a Bacterial infection of the skin which is caused by
And is also known by this name
Actinomyces israelii
Lumpy Jaw
Dental procedures, intestinal surgery, insertion of IUDs can initiate this Bacterial infection
Lumpy Jaw
Actinomyces israelii
This bite infection has surgical treatment and is caused by a variety of bacteria
Human bite
This bite is caused by Pasteurella multocida and treatment is penicillin
Animal bite
Bartonella henselea is the causative agent of this Bacterial Skin Infection
Cat scratch fever
The causative agent for this Bacterial skin infection is S. moniliforms (pleomorphic and produce L-forms)
Fevers come and go
Can recover without treatment or can cause death. Who knows what will happen
Streptobacillary Rat Bite Fever
Sporothrix schenckii, a dimorphic Fungus, causes this disease
Rose gardener’s disease
Symptoms of this FUNGAL Skin infection include a painless, ulcerating nodule appearing in a sequence in a linear patter
Rose gardener’s disease
Sporothrix schenckii (dimorphic fungus)
SPE-producing strains of Streptococcus pyogenes cause this Bacterial Skin Infection
Necrotizing fascitis
“Flesh-eating Disease”
Tetanus aka Lockjaw (Clostridium tetani)
Clostridial myonecrosis aka Gas Gangrene (Clostridium perfinges)
Actinomycosis aka Lumpy Jaw (Actinomyces israelii)
All have this in common
Diseases due to Anaerobic Bacteria
- Pasteurella multocida
- Bartonella hensalae
- Streptobacillus moniliformis
- Animal bites
- Cat scratch disease
- Rat bite fever