Chapter 23: Wound Infection

Question 1

Wound healing =

Answer 1

Granulation tissue

Question 2

Wound ___ at site seals off wound

Answer 2

Abcesses

Question 3

Coagulase causes plasma to clot

S epidermidis

S aureus

Which are their coagulase status

Answer 3

S epidermidis: Coagulase Negative

S aureus: Coagulase Positive

Question 4

Staphylococcus in general causes this production

Answer 4

Pus production

Question 5

S aureus Virulence factor name…

Attaches to fibrin, fibrogen, and plastic devices

Answer 5

Clumping factor

Question 6

S aureus Virulence factors

Makes holes in host cell membrane

Answer 6

A-Toxin

Question 7

S aureus Virulence factors

Kills neutrophils or degranulates them

Answer 7

Leukocidin

Question 8

What does Protein A in staphylococcus do

Answer 8

Covers the fc portion of the antibody, Hiding it from phagocytes

Question 9

This Streptococcus is a “ Flesh Eater”
Necrotizing fasciitis

Answer 9

Streptococcus pyogenes

Question 10

In Streptococcus pyogenes

Pyrogenic exotoxin A “super antigen” causes

Exotoxin B causes

Answer 10

Streptococcal toxic shock

Protease that destroys tissue proteins

Question 11

How is Necrotizing fasciitis dealt with in medical treatments

Answer 11

Surgery

Question 12

This skin infection most common in hospitals is the hardest to treat in burn victims

Answer 12

Pseudomonas aeruginosa

Question 13

Pseudomonas aeruginosa produces

Exoenzyme S which….

Exotoxin A which….

Answer 13

Exoenzyme S: Destroys Cell Membrane

Exotoxin A: Stops host cell protein synthesis

Question 14

To treat Pseudomonas aeruginosa skin infection what is done

Answer 14

Remove damaged infected tissue

Question 15

Clostridium tetani causes this Skin Infection

Answer 15

Tetanus (Lock Jaw)

Question 16

Pupils lose response to light and toxins prevents inhibitory neurons from functioning

Is this Skin Infection caused by this disease

Answer 16

Tetanus

Clostridium tetani

Question 17

TIG and vaccines are ways to fight against this Bacterial skin infection

Answer 17

Tetanus

Clostridium tetani

Question 18

Clostridium perfinges releases “a-toxin” which kills leukocytes and normal tissue. In this Bacterial Skin Infection

Answer 18

Gas gangrene

Clostridial myonecrosis

Question 19

Actinomycosis is a Bacterial infection of the skin which is caused by

And is also known by this name

Answer 19

Actinomyces israelii

Lumpy Jaw

Question 20

Dental procedures, intestinal surgery, insertion of IUDs can initiate this Bacterial infection

Answer 20

Lumpy Jaw

Actinomyces israelii

Question 21

This bite infection has surgical treatment and is caused by a variety of bacteria

Answer 21

Human bite

Question 22

This bite is caused by Pasteurella multocida and treatment is penicillin

Answer 22

Animal bite

Question 23

Bartonella henselea is the causative agent of this Bacterial Skin Infection

Answer 23

Cat scratch fever

Question 24

The causative agent for this Bacterial skin infection is S. moniliforms (pleomorphic and produce L-forms)

Fevers come and go

Can recover without treatment or can cause death. Who knows what will happen

Answer 24

Streptobacillary Rat Bite Fever

Question 25

Sporothrix schenckii, a dimorphic Fungus, causes this disease

Answer 25

Rose gardener’s disease

Question 26

Symptoms of this FUNGAL Skin infection include a painless, ulcerating nodule appearing in a sequence in a linear patter

Answer 26

Rose gardener’s disease

Sporothrix schenckii (dimorphic fungus)

Question 27

SPE-producing strains of Streptococcus pyogenes cause this Bacterial Skin Infection

Answer 27

Necrotizing fascitis

“Flesh-eating Disease”

Question 28

Tetanus aka Lockjaw (Clostridium tetani)
Clostridial myonecrosis aka Gas Gangrene (Clostridium perfinges)
Actinomycosis aka Lumpy Jaw (Actinomyces israelii)

All have this in common

Answer 28

Diseases due to Anaerobic Bacteria

Question 29

1. Pasteurella multocida
2. Bartonella hensalae
3. Streptobacillus moniliformis

Answer 29

1. Animal bites
2. Cat scratch disease
3. Rat bite fever