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Pathogenic Microbiology > Chapter 22: Skin Infections > Flashcards

Chapter 22: Skin Infections Flashcards

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Biology 101 flashcards
1
Q

What is the SALT of the immune system

A

Skin associated lymphatic tissue

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2
Q

Diphteroids, Staphylococci, and Fungi

Are associated with what in the skin

A

Normal flora

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3
Q

Found in the forehead, upper chest , and back. Oily regions

A

Diphtheroids

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4
Q

Malassezia is what kind of microbe commonly associated with the skin

A

Fungi

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5
Q

This Bacterial infection of the skin

Use strands of hair as route of invasion

Live in sebum & their blockage creates an increase of sebum

A

Acne vulgaris

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6
Q

A Furuncle is…

A

Boil filled with pus

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7
Q

Worse than a Furuncle

Large area of redness, swelling, pain, draining pus

A

Carbuncle

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8
Q

Causative agent of the skin Folliculitis is this bacteria…

A

Staphylococcus aureus

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9
Q

S aureus has many _____ including

Inhibit phagocytosis

Allow disguise, attachment, colonization
Enzymes that break down host tissue

Toxins that damage host

A

Virulence factors

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10
Q

_____ from Staphylococcus aureus causes Food Poisoning if injested and Toxic Shock if systemic

A

Enterotoxins

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11
Q

____ from Staphylococcus aureus causes scaled skin syndrome

A

Exfoliatin

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12
Q

Leukocidin in Staphylococcus aureus does what

A

Kills neutrophils/ makes them degranulate

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13
Q

_____ of Staphylococcus aureus Binds to the FC portion of the antibody, interfering with Opsonization, hence phagocytosis

A

Protein A

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14
Q

Staphylococci cannot survive on fomites

True or False

A

False

They survive well

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15
Q

SSSS

Epidemiology: which age group

Transmission

A

Any age. More common in New burns

Person to Person

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16
Q

Pathogenesis

______ is carried by the bloodstream to the epidermidis, causes the outer layer to blister and peel; loss of body fluid and 2ndary infection contribute to mortality

Name is disease and Causative agent

A

Exofoliatin

SSSS

Staphylococcus aureus

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17
Q

This Bacterial skin infection

Thin Walled blisters break 2 -5 days
Replaced by oozing crust drying plasma

Causative agents / main agent

Name is disease

A

Streptococcus pyogenes

Staphylococcus aureus

Impetigo

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18
Q

Epidemiology of Impetigo

Most common among ____

Spreads person-to-person, insects and fomites

Pathogenesis: enter through minor breaks in the skin

A

Poor children of hot humid areas

Impetigo

19
Q

About 1/2 of the cases of this Bacterial skin infection involve ______ (purplish spots) form due to small hemorrhages under skin

Symptoms include:

Flat pink rash appears first on wrist and ankles and speaks up

Name causative agent & Disease

A

Petechiae

Rickettsia rickettsii

Rocky mountain spotted fever

20
Q

This bacteria from this disease

Use host actin as an “actin tail” to move to adjacent host cells

Cells rupture releasing it in to the blood stream

A

Rickettsia rickettsii

21
Q

Small red bumps -> painless black eschar

Incubation: 1 - 7 days

Causative agent: _______ , an endospore forming Gram-positive rod

Pathogenesis: Exotoxin caused by cell death

Epidemiology: people who work with live stock. No person-to-person transmission

Vaccine available for at risk people

A

Bacillus anthracis

Cutaneous anthrax

22
Q

This viral disease

Begins as small, red spots (macules)
Progresses to little bumps (papules)
Finally small blisters (vesicles)

A

Varicella (chicken pox)

23
Q

Why don’t we scratch chicken pox

A

It will break the skin

Leading to a secondary infection

24
Q

Reactivation of Vericella (viral disease) will lead to this disease

A

Shingles

25
Q

What is the causative agent (virus) of chicken pox

Skin infection

A

Varicella-zoster virus (VZV)

26
Q

The pathogenesis of the Virus is

Enters respitory tract

Establishes an infection

Replicate in the lymph nodes

Travels to the skin via the bloodstream

Name disease and causative agent

A

Varicella

Varicella-zoster virus

27
Q

Stained preparations of infected cells of this virus _____ show INTRANUCLEAR INCLUSION BODIES
where virus reproduced

Skin infection

A

Varicella

Varicella-zoster Virus

28
Q

This virus travels to the sensory nerve ganglia and becomes latent: hiding in the nerve cell, eventually becoming what?

Skin infection

A

Varicella-zoster Virus

Shingles

29
Q

Congenital Varicella Syndrome ( from mother who had chicken pox early in pregnancy) may develop…

A

Cataracts & Underdeveloped limbs

30
Q

Immunocompromised at risk for severe VZV infections, partial protection achieved by …..

A

Injection of Hyperimmune globulin with high concentration of Antibody to VZV

31
Q

Rubeola is a viral skin infection AKA

A

Measles

32
Q

Subacute Sclerosing Panencephalitis is associated with which virus of the skin

A

Very rare, after Rubeola (measles) 2 - 10 years later ;death by brain degeneration

33
Q

MMR vaccine is for

A

Measles (rubeola), Mumps, Rubella (German Measles)

34
Q

Koplik spots are mucous membranes behind the molars are indicating this disease

Viral skin infection

A

Rubeola (measels)

35
Q

Rubella is a viral skin infection aka

A

German measles

36
Q

The 5th viral skin disease aka Erythema infectiosum

Is caused by _____

Preferentially infects bone marrow cells

A

Parvovirus B-19

37
Q

This caused by herpesvirus type 6 is common in children

Dangerous high fever

No vaccine or treatment

Skin infection

A

Roseola

38
Q

Warts are small benign tumors called

A

Papillomas

39
Q

Papillomavirus is the cause of

A

Warts

40
Q

Warts on the soles of the feet are called

A

Plantar warts

41
Q

Mycoses are diseases caused by

A

Fungi

42
Q

Eczema is this type of infection

A

Superficial cutaneous mycoses

43
Q

What kind of Fungus can invade hair, nails, keratin in skin

A

Dermatophytes

Pathogenic Microbiology (31 decks)

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