Ch 47 Flashcards
When does a human embryo begin to show distinctive features?
5 week
Order of embryonic development (frog) (6)
Zygote
Blastula
Gastrula
Tail-bud embryo (frog)
Larval Stage
Adult
What is the definition for Fertilization?
Formation of diploid zygote from haploid egg and sperm
Sperm ____ the protective layer around the egg
Penetrate
What binds to the molecules on the sperm surface?
Receptors on egg surface
What is Polyspermy?
The entry of multiple sperm nuclei into the egg
What prevents polyspermy
Changes at egg surface
What is triggered when the sperm meets the Egg?
Acrosomal Reaction
What releases hydrolytic enzyme that digest material surround the egg?
Acrosome
What causes fast block to polyspermy
Gamete contact depolarizes the egg cell membrane and causes the blockage
Fusion of egg and sperm initiate which reaction? What does it form?
Cortical Reaction
Forms fertilization envelope
What does the fertilization envelope act as
Slow block to polyspermy
Cortical reaction requires?
High concentration of calcium ion in the egg
What is cortical reaction caused by?
Change in Ca concentration
Spread of Ca correlates with appearance of the fertilization envelope
The rise of Ca in cytosol cause increase of what?
Cellular respiration and protein synthesis by the egg cell
When is an egg activated?
With rapid changes of metabolism (inc cell respiration and protein synthesis)
Where are proteins and mRNA needed for activation come from?
Already present in the egg
Because humans have internal fertilization, sperm must travel through ______ to get to the zone of pellucida
follicle cells
Sperm must travel through a layer of follicle cells surrounding the egg to reach?
The zone pellucida
extracellular matrix of egg
Sperm binding triggers?
Cortical Reaction
Time in mammals for the first cell division?
12-36 hours
What follows after fertilization?
Cleavage: period of rapid cell division without growth
Cleavage partitions the cytoplasm of one large cell into many smaller cells called?
Blastomeres
Ball of cells
Blastula
Blastula fluid filled cavity
Blastocoel
Why is cleavage asymmetric in frogs?
Due to distribution of yolk
Which pole has more yolk?
Vegetal pole
Which pole has less yolk?
Animal pole
The first two cleavage furrows in the frog form?
4 equal blastomeres
What is the third cleavage in a frog like
Forms unequal blastomeres due to yolk in vegetal hemisphere
Complete division of the egg and occurs in species with little/moderate amount of yolk?
Holoblastic Cleavage
Incomplete Division of the egg and occurs in species with lots of yolk?
Meroblastic cleavage
Morphogenesis
The process by which cells occupy their appropriate locations
Gastrulation
Organogensis
The movement of cells from the blastula surface to the interior of the embryo
Gastrulation
The formation of organs
Organogenesis
Gastrulation
Rearranges the cells of a blastula into a three layered embryo called a gastrula