Ch 45 pt 1 Flashcards

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1
Q

Chemical Signaling by hormones

A

Endocrine system

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2
Q

Endo

A

within

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3
Q

Crine

A

secrete

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4
Q

What is the Nervous system?

A

Network of specialized cells-neurons- that transmit signals along dedicated pathways

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5
Q

Animals use ___ to communicate in diverse ways

A

Chemical signals

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6
Q

Where do endocrine cells secrete hormones into?

A

Extracellular fluids

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7
Q

What system picks up the hormones

A

Circulatory system

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8
Q

What are Local Regulators?

A

Molecules that act over short distances reaching target cells by diffusion

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9
Q

What happens in Paracrine signaling?

A

Target cells lie near the secreting cells

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10
Q

What happens in Autocrine signaling?

A

Target cell is also the secreting cell

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11
Q

Para

A

Along side

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12
Q

Auto

A

Self

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13
Q

What are Prostaglandins?

A

Local Regulators that mediate signaling in paracrine and autocrine signaling
Function in the immune system and blood clotting

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14
Q

What is Synaptic Signaling?

A

Neurons form specialized junctions with target cells called synapses

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15
Q

What are Neurotransmitters?

A

At synapses, secreted molecules that diffuse short distances and bind to receptors on target cells

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16
Q

What are neurohormones? (2)

A

1) Secreted by neurosecretory cells
2) diffuse from nerve endings into the bloodstream

17
Q

Neuroendocrine signaling

A

Neurosecretory cells secrete neurohormones that diffuse from nerve endings into bloodstream

18
Q

How do some animals species communicate

A

Pheromones, chemicals that are released into the environment

19
Q

Pheromones uses (4)

A

1) Marking trails to food
2) Defining territories
3) Warning of predators
4) Attracting potential mates

20
Q

Local Regulators such as Prostaglandins are modified _______

A

fatty acids

21
Q

What are the 3 classes of local regulators?

A

1) prostaglandins
2) polypeptides
3) gases

22
Q

traits of Nitric Oxide (2)

A

1) Gas that function as both a local regulator and neurotransmitter
2) When O2 in blood falls, NO activates enzyme that results in vasodilation

23
Q

Hormones 3 major classes

A

1) Polypeptides (water soluble)
2) Steroids (lipid soluble)
3) Amines (water soluble)

24
Q

characteristics of Water soluble hormones (3)

A

1) Secreted by exocytosis
2) Travel freely in the bloodstream
3) Bind to cell surface receptors

25
Q

Lipid Soluble Hormones (4)

A

1) Diffuse across cell membranes
2) Travel in bloodstream bound to transport proteins
3) Diffuse through membrane of target cells
4) Bind to receptors in cytoplasm or nucleus of target cells

26
Q

What does Signal Transduction lead to?

A

Leads to responses in cytoskeleton, enzyme activation, or change in gene expression

27
Q

Usual response to a lipid-soluble hormone

A

Change in gene expression

28
Q

What happens when a steroid hormone binds to its cytosolic receptor

A

The receptor complex forms that will move into the nucleus where it acts as a transcriptional regulator of specific target genes

29
Q

Explain how Estradiol works

A

1) Binds to cytoplasmic receptor in liver cells of female birds and frogs
2) Activates transcription of genes needed to produce egg yolk

30
Q

explain response pathway for water-soluble hormones (3)

A

1) hormone binds to a receptor on the target cell
2) signal transduction pathway
3) activated protein stimulates response

31
Q

explain response pathway for lipid-soluble hormones (3)

A

1) steroid hormone binds to the cytosolic receptor
2) complex moves to the nucleus
3) the complex acts as a transcriptional regulator