Ch 45 pt 3 Flashcards
Describe the Thyroid hormone regulation pathway
1) hypothalamus secretes thyrotropin releasing hormone (TRH)
2) Causing the anterior pituitary to secrete thyroid-stimulating hormone (TSH)
3) TSH stimulates the release of thyroid hormone by the thyroid gland
Which hormone is the only iodine containing molecule synthesized in the body
Thyroid hormone
What causes low levels of the thyroid hormone?
lack of iodine
What does low levels of thyroid hormone lead to? (2)
1) lack of negative feedback for pituitary gland
2) thyroid enlargement and goiter
Describe hormonal regulation of growth
1) hypothalamus releases growth hormone regulating hormone (GHRH)
2) Anterior pituitary responds to GHRH and secretes Growth hormone
3) liver responds to GH and releases insulin-like growth factors (IGFs)
Growth Hormone (GH) has both _______and _______
Has tropic and nontropic effects
Tropic effect
Stimulates other endocrine glands
An excess of GH causes what?
Gigantism
What are Pituitary giants caused by?
1) Excessive GH during childhood
2) acromegaly if high levels continue in adulthood
What is Acromegaly caused by?
caused by tumors in pituitary
What is Short stature caused by? and how can it get treated?
Results from insufficient GH during childhood
Gets treated with GH injections before puberty
What gets released when Ca levels fall below a set point
Parathyroid hormone (PTH) by the parathyroid glands
What gets released when Ca levels rise above a set point
calcitonin by c-cell (parafollicular cell) of thyroid
What are the functions of PTH?
(3ways)
Increases level of blood Ca by:
1) Stimulates osteoclasts to release Ca from the bone
2) stimulates reabsorption of Ca in the kidneys
3) indirectly stimulates by promoting vitamin D production
What are the functions of Calcitonin?
(2ways)
Reduces levels of Ca by:
1) Stimulates osteoblasts to deposit Ca in bones
2) stimulates the secretion of Ca in the kidneys
Where are the Adrenal glands located?
Located above kidneys
Adrenal glands two glands
Adrenal medulla (inner)
Adrenal Cortex (outer)